Association between Macrophages and Specific Antibody Producing Cells [PDF]
Nature New Biology, 1971 MACROPHAGES are involved in the induction of the immune response to various antigens1,2 and ultrastructural observations suggest a close relationship between macrophages, lymphocytes and a variety of immunocompetent cells3,4, although the antibody specificities of the latter have not been demonstrated.
Miller, H R, Avrameas, S
semanticscholar +5 more sources
STUDIES ON ANTIBODY-PRODUCING CELLS [PDF]
The Journal of Experimental Medicine, 1970 Efferent lymph of the popliteal lymph nodes of rabbits was collected 4 days after a single footpad injection of SRBC. Thin-layer agar plating was done to isolate plaque-forming cells of the lymph for electron microscope examination, and the numbers of plaque-forming cells (PFC) in cells from the lymph and lymph nodes were determined.
Gudat, F G +3 more
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Use of Erythrocytes Sensitized with Purified Pneumococcal Polysaccharides for the Assay of Antibody and Antibody-producing Cells [PDF]
Applied microbiology, 1969 A method was described for the sensitization of erythrocytes with purified type-specific pneumococcal polysaccharide antigens using chromium chloride as a coupling agent.
Phillip J. Baker +2 more
semanticscholar +3 more sources
RESTRICTION OF THE CAPACITY TO RESPOND TO TWO ANTIGENS BY SINGLE PRECURSORS OF ANTIBODY-PRODUCING CELLS IN CULTURE [PDF]
Journal of Experimental Medicine, 1969 Experiments were designed to determine whether or not precursors of antibody-producing cells are restricted in the number of antigens to which they can respond.
David Osoba
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Detection and Enumeration of Antibody-Producing Cells by Specific Adherence of Antigen-Coated Bentonite Particles [PDF]
Journal of Immunology, 1966 The capacity of antigen-coated bentonite particles to adhere specifically to the surface of mmune lymphoid cells has provided the basis for a versatile and sensitive in vitro technique for the detection and enumeration of antibody-producing cells.
Phillip J. Baker +3 more
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BMC Biotechnology, 2007 Background Antibody-dependent cellular cytotoxicity (ADCC) is greatly enhanced by the absence of the core fucose of oligosaccharides attached to the Fc, and is closely related to the clinical efficacy of anticancer activity in humans in vivo ...
Shitara Kenya +6 more
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A nanowell platform to identify, sort and expand high antibody-producing cells [PDF]
Scientific ReportsIncreased use of therapeutic monoclonal antibodies and the relatively high manufacturing costs fuel the need for more efficient production methods. Here we introduce a novel, fast, robust, and safe isolation platform for screening and isolating antibody ...
Fikri Abali +7 more
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A CYCLICAL APPEARANCE OF ANTIBODY-PRODUCING CELLS AFTER A SINGLE INJECTION OF SERUM PROTEIN ANTIGEN [PDF]
Journal of Experimental Medicine, 1973 After a single intravenous injection of rabbits with aggregated HuIgG, IgM- and IgG-plaque-forming cells (PFC) in both the spleens and peripheral blood of rabbits peaked 5, 13, and 21 days after injection, while almost no PFC could be detected on days 8 ...
C G Romball, William O. Weigle
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ELECTRON MICROSCOPIC OBSERVATIONS ON ANTIBODY-PRODUCING CELLS IN LYMPH AND BLOOD [PDF]
The Journal of Experimental Medicine, 1966 Antibody-producing cells have been identified among cells obtained from efferent lymphatic vessels, the thoracic duct, and peripheral blood. These cells, which produced plaques of hemolysis and which were quite rare (20 to 50 per million), due in most instances to 19S antibody, were located and studied by electron microscopy.
Miriam B. Farber +4 more
openaire +4 more sources
Chimeric anti-HLA antibody receptor engineered human regulatory T cells suppress alloantigen-specific B cells from pre-sensitized transplant recipients [PDF]
Frontiers in ImmunologyOrgan transplantation is a lifesaving procedure, with 50,000 transplants happening every year in the United States. However, many patients harbor antibodies and B cells directed against allogeneic human leukocyte antigen (HLA) molecules, notably HLA-A2 ...
Jaime Valentín-Quiroga +6 more
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