Results 21 to 30 of about 1,768,583 (320)
Immortalisation of Human Antibody Producing Cells
Autoimmunity, 1992 (1992). Immortalisation of Human Antibody Producing Cells. Autoimmunity: Vol. 13, No. 3, pp. 249-258.
D. A. Isenberg, J. K. Kalsi
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Intrathymic differentiation of natural antibody-producing plasma cells in human neonates
Nature Communications, 2021 The thymus is known as the organ of T lymphocyte development. Here authors show that terminal B cell differentiation also takes place in the thymus of human neonates, leading to antibody production against commensal and pathogenic bacteria.
Hector Cordero +11 more
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Проблемы особо опасных инфекций, 2023 The aim of the work was to obtain and characterize hybridomas producing monoclonal antibodies to antigens of coronavirus SARS‑CoV‑2, promising for the construction of diagnostic immunochemical tests. Materials and methods.
G. V. Kuklina +7 more
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CD38-targeted therapy with daratumumab reduces autoantibody levels in multiple myeloma patients
Journal of Translational Autoimmunity, 2019 Autoantibody-producing plasma cells are frequently resistant to conventional immunosuppressive treatments and B-cell depletion therapy. As a result of this resistance, autoreactive plasma cells survive conventional therapy, resulting in persistent ...
Kristine A. Frerichs +5 more
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LONG-LIVED BONE MARROW PLASMA CELLS DURING IMMUNE RESPONSE TO ALPHA (1→3) DEXTRAN
Медицинская иммунология, 2015 Production kinetics and some functional properties of long-lived marrow plasma cells were studied in mice immunized with T-independent type 2 antigens. Alpha (1→3) dextran was used as an antigen for immunization.
I. N. Chernyshova +3 more
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Distribution and Morphology of Antibody-Producing Cells in Dueks
The Japanese Journal of Veterinary Science, 1980 アヒルにおける抗horseradish peroxidase抗体産生細胞の分布と形態とを, 光学顕微鏡的および電子顕微鏡的免疫細胞学によって検討した. 典型的な抗体産生細胞は脾臓赤髄ないし胚中心における形質細胞または大型リンパ球であった. 胚中心域には2型の陽性細胞が区別され, そのうちで多数をしめるものは樹枝状細胞で, 他は抗体産生細胞であったが, これらの抗体産生細胞は胚中心域以外に出現したものよりも遅く出現した. 脾臓白髄における他のリンパ球, すなわち動脈周囲リンパ球, 静脈周囲リンパ球および莢中心毛細管周囲リンパ球は抗体産生像を示さなかった.
Makoto Sugimura, Yoshiharu Hashimoto
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LOCALIZATION OF ANTIBODIES BY ELECTRON MICROSCOPY IN DEVELOPING ANTIBODY-PRODUCING CELLS
Journal of Cell Biology, 1965 The development of antibody-producing cells in the early stages of the secondary or hyperimmune response has been studied with the electron microscope in lymph nodes of adult chinchilla rabbits immunized with ferritin or apoferritin.
S. de Petris, G. Karlsbad
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Antibody-independent control of gamma-herpesvirus latency via B cell induction of anti-viral T cell responses. [PDF]
PLoS Pathogens, 2006 B cells can use antibody-dependent mechanisms to control latent viral infections. It is unknown whether this represents the sole function of B cells during chronic viral infection.
Kelly B McClellan +3 more
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AUTORADIOGRAPHIC STUDIES ON THE PROLIFERATION OF ANTIBODY-PRODUCING CELLS IN VITRO [PDF]
The Journal of Experimental Medicine, 1974 A rapid and reliable autoradiographic technique for plaque-forming cells (PFCs) using 14C rather than tritiated thymidine is described. Its application to PFCs developing in vitro shows that (a) practically all PFCs derive from precursors dividing steadily during the culture period, (b) PFC precursors divide in the absence of T-cell helper function ...
Thomas Hünig +2 more
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Regulatory mechanisms of B cell responses and the implication in B cell-related diseases
Journal of Biomedical Science, 2019 Terminally differentiated B cell, the plasma cell, is the sole cell type capable of producing antibodies in our body. Over the past 30 years, the identification of many key molecules controlling B cell activation and differentiation has elucidated the ...
Dong-Yan Tsai +3 more
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