Results 181 to 190 of about 751,456 (299)

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation [PDF]

Nat Commun, 2020
Hurlburt NK, Wan Y, Stuart AB, Feng J, McGuire AT, Stamatatos L, Pancera M.   +6 more
europepmc   +2 more sources

Development and experimental validation of computational methods for human antibody affinity enhancement. [PDF]

Brief Bioinform
Li J, Liao L, Zhang C, Huang K, Zhang P, Zhang JZH, Wan X, Zhang H.   +7 more
europepmc   +1 more source

Predicting antibody affinity changes upon mutations by combining multiple predictors. [PDF]

Sci Rep, 2020
Kurumida Y, Saito Y, Kameda T.
europepmc   +1 more source

Antibody Affinity Purification

BIO-PROTOCOL, 2012
openaire   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Author Correction: Pretrainable geometric graph neural network for antibody affinity maturation. [PDF]

Nat Commun
Cai H, Zhang Z, Wang M, Zhong B, Li Q, Zhong Y, Wu Y, Ying T, Tang J.   +8 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

SARS-CoV-2 mRNA vaccine induced higher antibody affinity and IgG titers against variants of concern in post-partum vs non-post-partum women. [PDF]

EBioMedicine, 2022
Lee Y, Grubbs G, Ramelli SC, Levine AR, Bathula A, Saharia K, Purcell M, Singireddy S, Dugan CL, Kirchoff L, Lankford A, Cipriano S, Curto RA, Wu J, Raja K, Kelley E, Herr D, Vannella KM, Ravichandran S, Tang J, Harris A, Sajadi M, Chertow DS, Grazioli A, Khurana S.   +24 more
europepmc   +1 more source

Display of Native SARS-CoV-2 Spike on Mammalian Cells to Measure Antibody Affinity and ADCC. [PDF]

Bio Protoc
Wilen RE, Nguyen AW, Qerqez AN, Maynard JA.   +3 more
europepmc   +1 more source