Results 31 to 40 of about 10,558,921 (293)

Digital Tools for Collaborative Design Processes

, 2021
Diverse practices of collaboration in design, research, teaching, or academia increasingly rely on digital online tools to facilitate processes of working and creating together. But a lot of the available digital platforms are not necessarily designed
Ibach, Merle, Greiner-Petter, Moritz
core   +1 more source

Critical by Design? [PDF]

, 2022
In its constructive and speculative nature, design has the critical potential to reshape prevalent socio-material realities. At the same time, design is inevitably normative, if not often violent, as it stabilises the past, normalises the present, and ...

core   +2 more sources

Computational Design of Epitope-Specific Functional Antibodies

Cell Reports, 2018
Summary: The ultimate goal of protein design is to introduce new biological activity. We propose a computational approach for designing functional antibodies by focusing on functional epitopes, integrating large-scale statistical analysis with multiple ...
Guy Nimrod, Sharon Fischman, Mark Austin, Asael Herman, Feenagh Keyes, Olga Leiderman, David Hargreaves, Marek Strajbl, Jason Breed, Shelley Klompus, Kevin Minton, Jennifer Spooner, Andrew Buchanan, Tristan J. Vaughan, Yanay Ofran   +14 more
doaj   +1 more source

Introducing Experience Goals into Packaging Design [PDF]

, 2016
Consumer experiences are an increasingly important driving force for commerce, affecting also packaging design. Yet, experience design for packages is rarely studied.
Roto, Virpi, Virpi Roto, Markus Joutsela, Joutsela, Markus   +3 more
core   +1 more source

Computer-aided antibody design. [PDF]

Protein Eng Des Sel, 2012
Recent clinical trials using antibodies with low toxicity and high efficiency have raised expectations for the development of next-generation protein therapeutics. However, the process of obtaining therapeutic antibodies remains time consuming and empirical.
Kuroda D, Shirai H, Jacobson MP, Nakamura H.   +3 more
europepmc   +4 more sources

Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans [PDF]

, 2013
Rabies kills many people throughout the developing world every year. The murine monoclonal antibody (mAb) 62-71-3 was recently identified for its potential application in rabies postexposure prophylaxis (PEP).
Both, L, Bulmer-Thomas, B., Banyard, AC, Selden, D., Altmann, F, Craig van Dolleweerd (406086), David Selden (4911475), Selden, D, Ashley C Banyard (16267520), Both, L., Banyard, A.C., Edward Wright (4468198), Bulmer-Thomas, B, Fooks, AR, Friedrich Altmann (33138), Wright, E, van Dolleweerd, C., Fooks, A.R., Ma, J.K.C., Julian K C Ma (16267529), Leonard Both (16267517), van Dolleweerd, C, Ma, JK, Wright, E., Altmann, F., Anthony R Fooks (16267526), Bianca Bulmer-Thomas (16267523)   +26 more
core   +1 more source

Evolution of phage display libraries for therapeutic antibody discovery

mAbs, 2023
Monoclonal antibodies (mAbs) and their derivatives have emerged as one of the most important classes of biotherapeutics in recent decades. The success of mAb is due to their high versatility, high target specificity, excellent clinical safety profile ...
Yang Zhang
doaj   +1 more source

Discovery and characterization of prolactin neutralizing monoclonal antibodies for the treatment of female-prevalent pain disorders

mAbs, 2023
Prolactin (PRL) has recently been demonstrated to elicit female-selective nociceptor sensitization and increase pain-like behaviors in female animals.
Stephanie Maciuba, Gregory D. Bowden, Harrison J. Stratton, Kazimierz Wisniewski, Claudio D. Schteingart, Juan C. Almagro, Philippe Valadon, Joshua Lowitz, Scott M. Glaser, Grace Lee, Mahdi Dolatyari, Edita Navratilova, Frank Porreca, Pierre J.M. Rivière   +13 more
doaj   +1 more source

Requests from Companies and Requirements for Design Education in Brazil: where do they meet? [PDF]

, 2018
In this paper, we study what companies request from applicants for graphic design positions in Brazil. Based on a document analysis of 371 job advertisements, we uncover 35 different types of requests which we structure in terms of (1) Design ...
Person, Oscar, Tonetto, Leandro Miletto, Rech Mandelli, Roberta, Leandro Miletto Tonetto, Tonetto, Leandro, Mandelli, Roberta Rech, Nicoletti Dziobczenski, Paulo, Roberta Rech Mandelli, Dziobczenski, Paulo Roberto Nicoletti, Paulo Roberto Nicoletti Dziobczenski, Oscar Person   +10 more
core   +1 more source

Antibody-Drug Conjugates for Cancer Therapy

, 2023
Antibody-drug conjugates (ADCs) take advantage of the specificity of a monoclonal antibody to deliver a linked cytotoxic agent directly into a tumour cell.
Sagun Parakh (9493061), Adam Parslow (9493046), Andrew Scott (9483443), Fook-Thean Lee (9491234), Hui Gan (9477872)   +4 more
core   +2 more sources