Results 141 to 150 of about 583,416 (296)

Anti-Modified Peptide Antibodies (AMPAs) in Rheumatoid Arthritis: Study of the Diagnostic Value of Citrullinated, Homocitrullinated, and Acetylated Fibrin/Filaggrin Chimeric Peptides

Diagnostics
Background/Objectives. The presence of anti-citrullinated peptide/protein antibodies (ACPAs), anti-carbamylated peptide/protein antibodies (anti-CarPs), and anti-acetylated peptide/protein antibodies (AAPAs), collectively termed as anti-modified peptide ...
Isabel Haro, Raul Castellanos-Moreira, Raimon Sanmartí, María José Gómara   +3 more
doaj   +1 more source

Antibody Isotype [PDF]

, 2020
openaire   +1 more source

Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics

Advanced Science, EarlyView.
The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang, Benjamin K. Law, Niles Huang, Katharine Goodwin, Celeste M. Nelson, Michelle M. Chan   +5 more
wiley   +1 more source

Change of Antibody Isotypes in FMD-Vaccinated Sows and Piglets

, 2010
[[abstract]]Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals. After the outbreak of serotype O1 FMD virus in Taiwan in 1997, pigs were extensively vaccinated.
林大盛 ; 李龍湖 ; 彭雲明
core  

Autoantibodies in SLE: Specificities, Isotypes and Receptors

, 2016
Systemic Lupus Erythematosus (SLE) is characterized by a wide spectrum of auto-antibodies which recognize several cellular components. The production of these self-reactive antibodies fluctuates during the course of the disease and the involvement of ...
Nicolas Charles, Barbara Dema
core   +1 more source

Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

Advanced Science, EarlyView.
Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami, Sanad M. El‐Khatib, Suhas Sureshchandra, Elise Nguyen, Janaki Manoja Vinnakota, Robert Zeiser, Shivashankar Othy, Munjal M. Acharya   +7 more
wiley   +1 more source

Evaluation of immuno-rolling circle amplification for multiplexed detection and profiling of antigen-specific antibody isotypes

Antibody characterization has become essential for diagnosis and development of therapeutic solutions in autoimmune, cardiovascular and infectious diseases.
Geukens, Nick, Madaboosi, Narayanan,, Kagro, Kadri, Nilsson, Mats,, Neumann, Felix,, Yeh, S., Mattson Langseth, Christoffer,, Breukers, Jolien, Vanhoorelbeke, Karen, Lammertyn, Jeroen, Horta, Sara   +10 more
core  

Developing Highly Effective Nanoparticle mRNA Therapeutic for Pediatric Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng, Wen Gao, Jonathan Do, Danli Lu, Ying‐Wei Lan, Andreas Damianos, Gautam Verma, Ali Al Siraj, Isabella Lowry, Lance Peter, Nicholas E. Banovich, Fei Sun, Hua He, Tanya V. Kalin, Vladimir V. Kalinichenko   +14 more
wiley   +1 more source

Monitoring SARS-CoV-2 IgA, IgM and IgG antibodies in dried blood and saliva samples using antibody proximity extension assays (AbPEA)

Scientific Reports
Using a modified proximity extension assay, total and immunoglobulin (Ig) class-specific anti-SARS-CoV-2 antibodies were sensitively and conveniently detected directly from ø1.2 mm discs cut from dried blood and saliva spots (DBS and DSS) without the ...
Mengqi Wang, Masood Kamali-Moghaddam, Liza Löf, Matilde Cortabarría Fernandez, Roger Díaz Codina, Fredrik H. Sterky, Mikael Åberg, Ulf Landegren, Hongxing Zhao   +8 more
doaj   +1 more source

Not all therapeutic antibody isotypes are equal: the case of IgM versus IgG in Pertuzumab and Trastuzumab. [PDF]

Chem Sci, 2020
Samsudin F, Yeo JY, Gan SK, Bond PJ.
europepmc   +1 more source