Results 121 to 130 of about 583,416 (296)
Measurement of serum IgG isotypes titers in immunized BALB/c mice.
, 2016 Profile of IgG isotypes in sera from immunized animal groups (40 μg, 20 μg and 10 μg CHIK-VLPs). Data represented as mean antibody titers with S.D. of ten Balb/c mice in each group Analysis was done by one way ANOVA, (Fisher LSD) #P $P §P ¤P < 0.0001 ...
Shweta Saraswat (3155073) +5 more
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Advanced Science, EarlyView.TUBA1B is consistently upregulated in hepatocellular carcinoma and sustains malignant progression by stabilizing G3BP2. By restraining TRIM25‐associated K48‐linked ubiquitination, TUBA1B preserves the G3BP2–IκBα complex and basal NF‐κB/p65 activity. Concurrent TUBA1B/G3BP2 upregulation identifies an aggressive HCC subgroup with enhanced p65 activation ...
Fen Lin +10 more
wiley +1 more source
Differential expression of liver fluke β-tubulin isotypes at selected life cycle stages
, 2013 We have shown that Fasciola hepatica expresses at least six β-tubulins in the adult stage of its life cycle, designated F.hep-β-tub1–6 (Ryan et al., 2008). Here we show that different complements of tubulin isotypes are expressed in different tissues and
Timson, David J. +8 more
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Advanced Science, EarlyView.AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang +21 more
wiley +1 more source
SARS-CoV-2 Antibody Isotypes in Systemic Lupus Erythematosus Patients Prior to Vaccination: Associations With Disease Activity, Antinuclear Antibodies, and Immunomodulatory Drugs During the First Year of the Pandemic. [PDF]
Front Immunol, 2021 Sjöwall J +7 more
europepmc +1 more source
, 2015 Bar graphs depict eluted mouse IgG (A) and IgG isotypes (B & C) from STC1 knockdown and control kidneys after nephrotoxic nephritis. Data represent the means ± SEM of 7 independent determinations for STC1 shRNA Tg and 5 independent determinations for ...
Luping Huang (320608) +8 more
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Advanced Science, EarlyView.Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu +6 more
wiley +1 more source
, 2014 BALB/c mice were mock-immunized with endotoxin free PBS or immunized with total CW proteins, CP proteins, or a combined CW and CP protein preparation in 50 µl of sterile PBS by nasal inhalation.
Karen L. Wozniak (229721) +7 more
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Advanced Science, EarlyView.NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu +10 more
wiley +1 more source
ELISA to determine relative antibody isotype titres in urine of VL patients and negative controls.
, 2016 Graph showing comparative optical density values of LAg-specific antibody isotypes; IgG, IgA, IgM, and IgE present in the urine samples of VL patients (n = 5), healthy controls (HC) (n = 3) and other diseases (OD) (n = 4) at 492nm.
Pradyot Bhattacharya (245137) +9 more
core +1 more source