Results 31 to 40 of about 9,814,118 (327)

Cautionary notes on the use of NF-κB p65 and p50 antibodies for CNS studies

open access: yesJournal of Neuroinflammation, 2011
Background The characterization and cellular localization of transcription factors like NF-κB requires the use of antibodies for western blots and immunohistochemistry.
Listwak Samuel J   +3 more
doaj   +1 more source

IgM Antibodies Can Access Cryptic Antigens Denied to IgG: Hypothesis on Novel Binding Mechanism

open access: yesFrontiers in Immunology, 2019
Antibodies are well-known protein mediators of immunity. IgM is the primordial member and the neglected sibling of the later-evolved and more proficient IgG in regard to their therapeutic and diagnostic use.
Eric Chun Yiu Law   +7 more
doaj   +1 more source

Machine Learning to Quantify In Situ Humoral Selection in Human Lupus Tubulointerstitial Inflammation

open access: yesFrontiers in Immunology, 2020
In human lupus nephritis, tubulointerstitial inflammation (TII) is associated with in situ expansion of B cells expressing anti-vimentin antibodies (AVAs). The mechanism by which AVAs are selected is unclear.
Andrew J. Kinloch   +8 more
doaj   +1 more source

Antibodies to guanosine [PDF]

open access: yesFEBS Letters, 1984
Bovine serum albumin conjugates of guanosine prepared by the periodate method was used as immunogen to elicit guanosine antibodies in rabbits. The specificities of the antibodies were studied by the inhibition of their binding to [3H]Gox‐red, [32P]DNA and [3H]RNA by related non‐radioactive compounds.
Iswari, S, Jacob, TM
openaire   +3 more sources

Biochemical patterns of antibody polyreactivity revealed through a bioinformatics-based analysis of CDR loops

open access: yeseLife, 2020
Antibodies are critical components of adaptive immunity, binding with high affinity to pathogenic epitopes. Antibodies undergo rigorous selection to achieve this high affinity, yet some maintain an additional basal level of low affinity, broad reactivity
Christopher T Boughter   +6 more
doaj   +1 more source

Structurally Mapping Antibody Repertoires

open access: yesFrontiers in Immunology, 2018
Every human possesses millions of distinct antibodies. It is now possible to analyze this diversity via next-generation sequencing of immunoglobulin genes (Ig-seq).
Konrad Krawczyk   +16 more
doaj   +1 more source

Severe Acute Respiratory Syndrome Coronavirus 2−Specific Antibody Responses in Coronavirus Disease Patients

open access: yesEmerging Infectious Diseases, 2020
A new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently emerged to cause a human pandemic. Although molecular diagnostic tests were rapidly developed, serologic assays are still lacking, yet urgently needed ...
Nisreen M. A. Okba   +18 more
semanticscholar   +1 more source

Antibody variable region engineering for improving cancer immunotherapy

open access: yesCancer Communications, 2022
The efficacy and specificity of conventional monoclonal antibody (mAb) drugs in the clinic require further improvement. Currently, the development and application of novel antibody formats for improving cancer immunotherapy have attracted much attention.
Hantao Lou, Xuetao Cao
doaj   +1 more source

Platelet antibody of blood donors in Suzhou

open access: yesZhongguo shuxue zazhi, 2022
Objective To study the incidence and specificity of platelet antibody in blood donors in Suzhou, analyze the distribution characteristics of platelet antibody in blood donors in this area, and explore the significance of platelet antibody detection in ...
Li DONG   +8 more
doaj   +1 more source

Antibody Detection and Dynamic Characteristics in Patients with COVID-19

open access: yesClinical Infectious Diseases, 2020
Background The corona virus disease 2019 (COVID-19) caused by the corona virus 2 (SARS-CoV-2) has been rapidly spreading nationwide and abroad. A serologic test to identify antibody dynamics and response to SARS-CoV-2 was developed.
Fei-Xiang Xiang   +12 more
semanticscholar   +1 more source

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