Results 251 to 260 of about 6,504,034 (299)

Synthesis, Molecular Modeling and Assessment of Anticancer Activity of New Potential CYP17A1 Inhibitors. [PDF]

Molecules
Jastrzębski MK, Korga-Plewko A, Iwan M, Kubik J, Stachniuk A, Fornal E, Wróbel TM, Kaczor AA.   +7 more
europepmc   +1 more source

Synthesis, X-Ray Analysis, Anticancer Activity, Computational, and in Silico Studies of New Thiophene Pyrazole Conjugates. [PDF]

ChemistryOpen
Muhsinah AB, Kheder NA, Elhaty IA, Mabkhot YN.   +3 more
europepmc   +1 more source

Investigating the anticancer activity of eravacycline in pancreatic cancer via target-based deep learning and experimental validation. [PDF]

Brief Bioinform
Jabarin A, Shtar G, Feinshtein V, Mazuz E, Shapira B, Rokach L, Ben-Shabat S.   +6 more
europepmc   +1 more source

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Anticancer activity of seaweeds

Drug Discovery Today, 2018
Cancer is a major health problem worldwide and still lacks fully effective treatments. Therefore, alternative therapies, using natural products, have been proposed. Marine algae are an important component of the marine environment, with high biodiversity, and contain a huge number of functional compounds, including terpenes, polyphenols, phlorotannins,
Anllely G, Gutiérrez-Rodríguez, Claudia, Juárez-Portilla, Tatiana, Olivares-Bañuelos, Rossana C, Zepeda   +3 more
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Anticancer Activity of Ferrocenylthiosemicarbazones

Anti-Cancer Agents in Medicinal Chemistry, 2014
Aliphatic and aromatic ferrocenylthiosemicarbazones were synthesized. The characterization of the new ferrocenylthiosemicarbazones was done by IR, (1)H-NMR and (13)C-NMR spectroscopy, elemental analysis and X-ray diffraction studies. The biological activity of the obtained compounds was assessed in terms of anticancer activity.
Cortez-Maya, Sandra, Klimova, Elena, Flores-Alamo, Marcos, Martínez-Klimova, Elena, Ramírez-Ramírez, Arturo, Ramírez Apan, Teresa, Martínez-García, Marcos   +6 more
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Advances in Chalcones With Anticancer Activities

Recent Patents on Anti-Cancer Drug Discovery, 2014
Chalcones are naturally occurring compounds exhibiting broad spectrum biological activities including anticancer activity through multiple mechanisms. Literature on anticancer chalcones highlights the employment of three pronged strategies, namely; structural manipulation of both aryl rings, replacement of aryl rings with heteroaryl scaffolds ...
Devarajan Karunagaran, Manivannan Elangovan, Piyush Trivedi   +2 more
exaly   +3 more sources

The anticancer activity of carbazole alkaloids

Archiv der Pharmazie, 2021
AbstractChemotherapy is the first choice for the majority of cancers, but severe side effects and drug resistance restrict the actual clinical efficacy. Carbazole alkaloids, mainly from the Rutaceae family, possess favorable donor ability, good planarity, rich photophysical properties, and excellent biocompatibility.
Feng Song, Dan Liu, Xiankai Huo, Di Qiu
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Classification Models for Anticancer Activity

Current Topics in Medicinal Chemistry, 2013
Despite significant research in understanding of neoplastic diseases, the success rate for oncology drugs is relatively very low. A major challenge before the scientific community is to design new chemical entities that will be highly selective for cancer cells so as to minimize side effects.
R, Dutt, A K, Madan
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Differentiation, cancer, and anticancer activity

Biochemistry and Cell Biology, 1988
Carcinogenesis is a multistep process that results from the development of a variety of defects in the control of differentiation and proliferation. To investigate this concept further, 3T3 T mesenchymal stems cells were employed to establish that a distinct sequence of biological processes is involved in the control of differentiation and ...
C Y, Tzen, D N, Estervig, P, Minoo, M, Filipak, P B, Maercklein, B J, Hoerl, R E, Scott   +6 more
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