Results 61 to 70 of about 181,241 (287)

Glycemic Control Potential of Chemically Characterized Extract from Withania frutescens L. Roots in Severe Diabetes-Induced Mice

Applied Sciences, 2021
Diabetes mellitus is a metabolic syndrome that causes impairment, mortality, and many other complications. Insulin and several synthetic medications are currently used in the treatment of diabetes.
Abdelfattah El Moussaoui, Hamza Mechchate, Mohammed Bourhia, Imane Es-safi, Ahmad Mohammad Salamatullah, Mohammed Saeed Alkaltham, Heba Khalil Alyahya, Dalila Bousta, Amina Bari   +8 more
doaj   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Dittrichia viscosa L. Leaves: A Valuable Source of Bioactive Compounds with Multiple Pharmacological Effects

Molecules, 2022
This work focused on the leaves of Dittrichia viscosa, a plant used in Mediterranean folk medicine. Compared to water extract, the methanolic extract had higher antioxidant effects.
Reda Ben Mrid, Najat Bouchmaa, Imad Kabach, Zakia Zouaoui, Houda Chtibi, Mohammed El Maadoudi, Ayoub Kounnoun, Francesco Cacciola, Yassine Oulad El Majdoub, Luigi Mondello, Abdelmajid Zyad, Mohamed Nhiri   +11 more
doaj   +1 more source

Effect of Urtica dioica L extract on quantitative morphometric alterations of liver parenchymal cells in STZ diabetic rats [PDF]

, 2009
Diabetes is associated with several structural and functional liver abnormalities that affect glycogen and lipid metabolism. In this study, an attempt was made to evaluate the effects of hydroalcoholic extract of Urtica dioica leaves on Quantitative ...
Farsi, M.M., Ghafari, S., Golalipour, M.J.   +2 more
core   +1 more source

Metformin‐Based Covalent Organic Frameworks With Excellent Biosafety and High Efficiency against Pathogenic Microorganisms

Advanced Science, EarlyView.
This work presents the first metformin‐based COFs featuring built‐in biosafety and a unique triple‐synergy mechanism. This scalable platform achieves broad‐spectrum eradication of bacteria and viruses, enabling reusable protective membranes with exceptional biocompatibility for advanced biomedical applications and personal protection.
Jia‐Yi Liu, Hong Jiang, Lei Ma, Jin‐Yi Yu, Ming‐Yi Yang, Hao‐Ru Wang, Jun‐Yuang Tang, Shengfeng Huang, Wei Yi, Meng Lu, Ya‐Qian Lan, Xu‐Jia Hong   +11 more
wiley   +1 more source

Amelioration of hyperglycaemia and modulation of antioxidant status by Alcea rosea seeds in alloxan-induced diabetic rats

Pharmaceutical Biology, 2017
Context: Alcea rosea L. (Malvaceae) has various medicinal uses including anticancer, anti-inflammatory and analgesic properties. However, there is no report on its antidiabetic activity.
Parvaiz A. Dar, Fasil Ali, Ishfaq A. Sheikh, Showkat A. Ganie, Tanveer A. Dar   +4 more
doaj   +1 more source

The Antidiabetic Activity of Curry Leaves “Murraya Koenigii” on the Glucose Levels, Kidneys, and Islets of Langerhans of Rats with Streptozotocin Induced Diabetes [PDF]

, 2017
Background: The aims of this study were to explore the antihyperglycemic effect of curry leaves, Murraya koenigii "MK" aqueous extract, and to examine its possible protective effects on the islets of Langerhans and kidneys of streptozotocin (STZ ...
Al-Ani, I. M. (Imad), Alazzawi, K. S. (Khalid), Santosa, R. I. (Rahajoe), Saxena, A. K. (Anil), Yankuzo, M. H. (Muhammad)   +4 more
core  

Laminaria japonica Extract Enhances Intestinal Barrier Function by Altering Inflammatory Response and Tight Junction-Related Protein in Lipopolysaccharide-Stimulated Caco-2 Cells. [PDF]

, 2019
In the normal physiological state, intestinal epithelial cells act as a defensive frontline of host mucosal immunity to tolerate constant exposure to external stimuli.
Ding, Eom, Fawaz G Haj, Folin, Guiguo Zhang, Heo, Hyo-Seon Yang, Inhae Kang, Myoungsook Lee, Shirosaki, Shon, Wells, Wolfrom, Yunkyoung Lee   +13 more
core   +1 more source

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

Advanced Science, EarlyView.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély, István Narozsny, Levente Szarka, Daniel V. Veres, Peter Csermely, Dávid Keresztes   +5 more
wiley   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source