Results 221 to 230 of about 68,714 (277)

Human Colitis‐on‐Chip Model Reveals Dual Roles of Butyrate in Epithelial and Macrophage Defense Against Candida albicans Tissue Invasion

Small, EarlyView.
This study establishes a human immunocompetent colitis‐on‐chip model that mimics inflamed gut mucosa and enables quantitative analysis of Candida albicans tissue invasion under DSS‐induced injury. It reveals that microbiota‐derived butyrate simultaneously stabilizes epithelial junctions and reprograms macrophages via HDAC/NLRP3‐dependent mechanisms ...
Manuel Allwang, Maximilian Wipplinger, Parastoo Akbarimoghaddam, Raquel Alonso‐Roman, Zoltan Cseresnyes, Axel Dietschmann, Valentin Wegner, Adrian Feile, Yann Bachelot, Maria Warschinke, Mohamed I. Abdelwahab Hassan, Sonnhild Mittag, Otmar Huber, Bernhard Hube, Mark S. Gresnigt, Marc Thilo Figge, Alexander S. Mosig   +16 more
wiley   +1 more source

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance. [PDF]

J Vis Exp, 2017
Biswas C, Chen SC, Halliday C, Martinez E, Rockett RJ, Wang Q, Timms VJ, Dhakal R, Sadsad R, Kennedy KJ, Playford G, Marriott DJ, Slavin MA, Sorrell TC, Sintchenko V.   +14 more
europepmc   +1 more source

The photoswitchable ABAMIs for the future regulation of GWT1 in a spatiotemporal level

Smart Molecules, EarlyView.
The GWT1‐targeted azobenzene‐aminopyridine derivatives (ABAMIs), sensitive to the light at wavelengths from 365 to 520 nm, are separately developed as photochromic ligands to regulate bioactivity as well as the GWT1 functions. These molecules are smart tools in photopharmacological studies, giving an innovative method for understanding functional GWT1 ...
Qian Ding, Zongying Li, Zaiwei Xiao, Siting Zhang, Zimai Liu, Xiaoguang Shao, Zhong Li, Wen Fu, Xusheng Shao   +8 more
wiley   +1 more source

Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems

The Chemical Record, EarlyView.
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Romelly Eugenia Rojas Ramírez, Tielle Moraes de Almeida, Daiani Canabarro Leite, Gilson Zeni   +3 more
wiley   +1 more source

Engineering Nanoscale Frontiers: Valve Metal Oxide Nanostructures From Fundamentals to Multifunctional Biomedical Applications

The Chemical Record, EarlyView.
Valve metal oxide nanostructures such as TiO2, Ta2O5, Nb2O5, ZrO2, and HfO2 are emerging as versatile biomedical platforms due to their tunable surface properties, exceptional stability, and inherent biocompatibility. This review highlights their synthesis, physicochemical properties, and biological interactions, addressing their roles in advanced ...
Nina Kummer, Désirée Gül, İdris Sargin, Mustafa Dolaz, Dzmitry Shcharbin, Shirley K. Knauer, Burcu Önal Acet, Emrah Dikici, Mingyuan Gao, Mehmet Odabaşı, Ömür Acet, Roland H. Stauber   +11 more
wiley   +1 more source

Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms

The Chemical Record, EarlyView.
Additive manufacturing enables the rational design of structured antimicrobial platforms across multiple length scales, from nanofibrous scaffolds and droplet microreactors to 3D and 4D printed constructs. By engineering confinement, interfacial chemistry, and stimuli‐responsive release, these systems exert localized action through complementary ...
Giorgia Puleo, Silvia Orecchio, Dario Savoca, Claudia Pellerito, Vittorio Ferrara, Vincenzo Piscopo, Sebastiano Alberto Fortuna, Alessandra Giardina, Bruno Pignataro, Paola Costanzo, Floriana Campanile, Giuseppe Arrabito   +11 more
wiley   +1 more source

Agricultural Fungicide Mancozeb in Leaf Litter Enhances Survival and Growth of Aedes aegypti (Diptera: Culicidae)

Environmental Toxicology, EarlyView.
ABSTRACT Mancozeb is one of the most widely used agricultural fungicides, exhibiting strong efficacy against a broad spectrum of phytopathogenic fungi. However, its widespread application comes at the cost of environmental contamination. Here, we show the effects of Inga vera leaf litter contamination with Mancozeb on life‐history traits of Aedes ...
Heloise Restello Remus, Gilberto Dinis Cozzer, João Tauchert, Raquel de Brito, Cássia Alves Lima‐Rezende, Jacir Dal Magro, Natalia Bastiani da Luz, Daniel Albeny‐Simões, Renan de Souza Rezende   +8 more
wiley   +1 more source

Reusing health records from farm animal practices at scale: A potential complementary method of surveillance

Veterinary Record, EarlyView.
Abstract Background Disease in primary care frequently represents a surveillance blind spot, particularly for diseases affecting farm animals. Methods Electronic health records (EHRs) were collected from four farm animal veterinary practices in Wales (February 2024‒January 2025) as part of a pilot study.
Beverley Hopkins, Peers Davies, Peter‐John Noble, Anna Bunford‐Davies, April Lawson, Gina Pinchbeck, Ifan Lloyd, Robert Smith, Alan D. Radford   +8 more
wiley   +1 more source

Twenty‐Five Years of the Environmental Stress Response and the Enduring Power of Yeast in Stress Biology

Yeast, EarlyView.
ABSTRACT All organisms must be able to sense and respond to adverse environments, especially those that threaten cellular integrity. The age of genomics clarified the breadth and specificity of cellular stress responses, including in free‐living microbes directly exposed to a changing environment.
Audrey P. Gasch
wiley   +1 more source

Patterns of Surgical Prophylaxis Prescribing for Dentoalveolar Procedures in Australian Hospitals: 2016–2022

Australian Dental Journal, EarlyView.
ABSTRACT Background Antimicrobials are an adjunctive therapy in clinical dentistry. In dentoalveolar surgery, antimicrobials are not routinely required for surgical prophylaxis. This retrospective analysis of the Australian Surgical National Antimicrobial Prescribing Survey (Surgical NAPS) dataset aimed to evaluate the guideline compliance and ...
Jane Chen, Marietta Taylor, Rodney James, Karin Thursky, Michael McCullough, Leanne Teoh, Courtney Ierano   +6 more
wiley   +1 more source