Results 11 to 20 of about 85,603 (246)

Repurposing non-antifungal drugs auranofin and pentamidine in combination as fungistatic antifungal agents against C. albicans

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Fungal infection is a serious global health issue, causing approximately 1.5 million mortalities annually. However, clinically available anti-fungal drugs are limited, especially for multidrug-resistant fungal infections.
Jiaying Lin   +7 more
doaj   +1 more source

Antifungal Polymeric Materials and Nanocomposites

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Rising global populations due to medicinal advancements increases the patient population susceptible to superficial and severe fungal infections. Fungi often implicated in these diseases includes the dermatophytes (Microsporum spp., Epidermophtyon spp ...
Winnie Ntow-Boahene   +2 more
doaj   +1 more source

Fungal infections: Pathogenesis, antifungals and alternate treatment approaches

open access: yesCurrent Research in Microbial Sciences, 2022
Increasing incidence of fungal infections of recent times requires immediate intervention. Fungal infections are seldom construed at initial stages that intensify the severity of infections and complicate the treatment procedures. Fungal pathogens employ
G.Kiran Kumar Reddy   +2 more
doaj   +1 more source

Three New Isoflavonoid Glycosides from the Mangrove-Derived Actinomycete Micromonospora aurantiaca 110B

open access: yesMarine Drugs, 2019
The mangrove ecosystem is a rich resource for the discovery of actinomycetes with potential applications in pharmaceutical science. Besides the genus Streptomyces, Micromonospora is also a source of new bioactive agents.
Rui-Jun Wang   +8 more
doaj   +1 more source

Overproduction of gentamicin B in industrial strain Micromonospora echinospora CCTCC M 2018898 by cloning of the missing genes genR and genS

open access: yesMetabolic Engineering Communications, 2019
In pharmaceutical industry, isepamicin is mainly manufactured from gentamicin B, which is produced by Micromonospora echinospora as a minor component of the gentamicin complex.
Yingying Chang   +8 more
doaj   +1 more source

Fungal Infections as an Uprising Threat to Human Health: Chemosensitization of Fungal Pathogens With AFP From Aspergillus giganteus

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Occurrence and intensity of systemic invasive fungal infections have significantly risen in recent decades with large amount of mortality and morbidity rates at global level.
Kavitha Dhandapani   +3 more
doaj   +1 more source

Antifungal Drugs and Drug-Induced Liver Injury: A Real-World Study Leveraging the FDA Adverse Event Reporting System Database

open access: yesFrontiers in Pharmacology, 2022
Aims: We aimed to estimate the risk of drug-induced liver injury (DILI) from various antifungal treatments with azoles and echinocandins causing in real-world practice.Methods: We performed disproportionality and Bayesian analyses based on data from the ...
Zhi-Xuan Zhou   +13 more
doaj   +1 more source

Pharmaceutical Pollution: Azole Antifungal Drugs and Resistance of Opportunistic Pathogenic Yeasts in Wastewater and Environmental Water

open access: yesApplied and Environmental Soil Science, 2021
The occurrence of residual antifungal agents through indiscriminate prophylactic use and inappropriate disposal has been reported in wastewater treatment plants (WWTPs), surface water, and groundwater environments. Opportunistic pathogenic aquatic yeasts
Mzimkhulu E. Monapathi   +6 more
doaj   +1 more source

Identification and Elimination of Antifungal Tolerance in Candida auris

open access: yesBiomedicines, 2023
Antimicrobial resistance is a global health crisis to which pathogenic fungi make a substantial contribution. The human fungal pathogen C. auris is of particular concern due to its rapid spread across the world and its evolution of multidrug resistance ...
Samira Rasouli Koohi   +3 more
doaj   +1 more source

Susceptibilities of Malassezia strains from pityriasis versicolor, Malassezia folliculitis and seborrheic dermatitis to antifungal drugs

open access: yesHeliyon, 2020
The human pathogenic yeast genus Malassezia may be an etiological agent of skin disorders and has received considerable attention from dermatologists in recent years.
Kaiqin Wang   +12 more
doaj   +1 more source

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