Results 21 to 30 of about 92,209 (296)

Antifungal Drug Repurposing [PDF]

open access: yesAntibiotics, 2020
Control of fungal pathogens is increasingly problematic due to the limited number of effective drugs available for antifungal therapy. Conventional antifungal drugs could also trigger human cytotoxicity associated with the kidneys and liver, including the generation of reactive oxygen species.
Jong H. Kim   +7 more
openaire   +3 more sources

Antifungal drugs prescription pattern in a tertiary care teaching hospital in South India

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2023
Background: Fungal infections are a major threat to human health. Immunocompromised patients are more susceptible to fungal infections which may be from superficial to systemic fungal infections. Proper diagnosis and appropriate prescription is essential
Subashree A, Anuradha C R, Reena G R
doaj   +1 more source

Development and research progress of anti-drug resistant fungal drugs

open access: yesJournal of Infection and Public Health, 2022
With the widespread use of immunosuppressive agents and the increase in patients with severe infections, the incidence of fungal infections worldwide has increased year by year.
Xiangyi Cui   +3 more
doaj   +1 more source

Pharmacovigilance of triazole antifungal agents: Analysis of the FDA adverse event reporting system (FAERS) database

open access: yesFrontiers in Pharmacology, 2022
Triazole antifungal drugs (TAD) are widely used to treat invasive fungal infections due to their broad antifungal spectrum and low toxicity. Despite their preference in the clinic, multiple Adverse Events (AE) are still reported each year.
Jianxing Zhou   +8 more
doaj   +1 more source

Antifungal and Immunomodulatory Ingredients from Traditional Chinese Medicine

open access: yesAntibiotics, 2022
Fungal infections have become a growing public health challenge due to the clinical transmission of pathogenic fungi. The currently available antifungal drugs leave very limited choices for clinical physicians to deal with such situation, not to mention ...
Hua Zhong, Lei Han, Ren-Yi Lu, Yan Wang
doaj   +1 more source

Repurposing non-antifungal drugs auranofin and pentamidine in combination as fungistatic antifungal agents against C. albicans

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Fungal infection is a serious global health issue, causing approximately 1.5 million mortalities annually. However, clinically available anti-fungal drugs are limited, especially for multidrug-resistant fungal infections.
Jiaying Lin   +7 more
doaj   +1 more source

Antifungal Polymeric Materials and Nanocomposites

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Rising global populations due to medicinal advancements increases the patient population susceptible to superficial and severe fungal infections. Fungi often implicated in these diseases includes the dermatophytes (Microsporum spp., Epidermophtyon spp ...
Winnie Ntow-Boahene   +2 more
doaj   +1 more source

Fungal infections: Pathogenesis, antifungals and alternate treatment approaches

open access: yesCurrent Research in Microbial Sciences, 2022
Increasing incidence of fungal infections of recent times requires immediate intervention. Fungal infections are seldom construed at initial stages that intensify the severity of infections and complicate the treatment procedures. Fungal pathogens employ
G.Kiran Kumar Reddy   +2 more
doaj   +1 more source

Three New Isoflavonoid Glycosides from the Mangrove-Derived Actinomycete Micromonospora aurantiaca 110B

open access: yesMarine Drugs, 2019
The mangrove ecosystem is a rich resource for the discovery of actinomycetes with potential applications in pharmaceutical science. Besides the genus Streptomyces, Micromonospora is also a source of new bioactive agents.
Rui-Jun Wang   +8 more
doaj   +1 more source

Overproduction of gentamicin B in industrial strain Micromonospora echinospora CCTCC M 2018898 by cloning of the missing genes genR and genS

open access: yesMetabolic Engineering Communications, 2019
In pharmaceutical industry, isepamicin is mainly manufactured from gentamicin B, which is produced by Micromonospora echinospora as a minor component of the gentamicin complex.
Yingying Chang   +8 more
doaj   +1 more source

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