Results 21 to 30 of about 1,272,091 (279)

Antifungal and Immunomodulatory Ingredients from Traditional Chinese Medicine

open access: yesAntibiotics, 2022
Fungal infections have become a growing public health challenge due to the clinical transmission of pathogenic fungi. The currently available antifungal drugs leave very limited choices for clinical physicians to deal with such situation, not to mention ...
Hua Zhong, Lei Han, Ren-Yi Lu, Yan Wang
doaj   +1 more source

Repurposing non-antifungal drugs auranofin and pentamidine in combination as fungistatic antifungal agents against C. albicans

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Fungal infection is a serious global health issue, causing approximately 1.5 million mortalities annually. However, clinically available anti-fungal drugs are limited, especially for multidrug-resistant fungal infections.
Jiaying Lin   +7 more
doaj   +1 more source

Antifungal Polymeric Materials and Nanocomposites

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Rising global populations due to medicinal advancements increases the patient population susceptible to superficial and severe fungal infections. Fungi often implicated in these diseases includes the dermatophytes (Microsporum spp., Epidermophtyon spp ...
Winnie Ntow-Boahene   +2 more
doaj   +1 more source

Treatment of atopic dermatitis using topical antifungal drugs: A meta‐analysis

open access: yesDermatologic Therapy, 2022
Several studies have focused on treating atopic dermatitis (AD) using topical antifungal drugs. However, their findings are inconsistent. This meta‐analysis of randomized controlled trials (RCTs) aimed to evaluate the safety and efficacy of topical ...
Dan He   +5 more
doaj   +1 more source

Reshaping Echinocandin Antifungal Drugs to Circumvent Glucan Synthase Point Mutation-Mediated Resistance [PDF]

open access: yes, 2023
Echinocandins are important antifungal drugs that inhibit the activity of the membrane-bound glucan synthase complex, which is responsible for the synthesis of the fungal cell wall β-(1,3)-glucan.
Moriah, Jospe-Kaufman   +3 more
core   +2 more sources

Three New Isoflavonoid Glycosides from the Mangrove-Derived Actinomycete Micromonospora aurantiaca 110B

open access: yesMarine Drugs, 2019
The mangrove ecosystem is a rich resource for the discovery of actinomycetes with potential applications in pharmaceutical science. Besides the genus Streptomyces, Micromonospora is also a source of new bioactive agents.
Rui-Jun Wang   +8 more
doaj   +1 more source

Fungal infections: Pathogenesis, antifungals and alternate treatment approaches

open access: yesCurrent Research in Microbial Sciences, 2022
Increasing incidence of fungal infections of recent times requires immediate intervention. Fungal infections are seldom construed at initial stages that intensify the severity of infections and complicate the treatment procedures. Fungal pathogens employ
G.Kiran Kumar Reddy   +2 more
doaj   +1 more source

Exploring hidden dimensions of soil fungal biodiversity: A simple technique to detect soil fungi resistant to antifungal compounds [PDF]

open access: yes, 2010
Soils are known to be ultimate and complex reservoirs of microbial diversity. The complex dimensions of bacterial and fungal diversity in tropical soils and microbial community dynamics are underexplored.
Sonashia Velho-Pereira   +1 more
core   +1 more source

Overproduction of gentamicin B in industrial strain Micromonospora echinospora CCTCC M 2018898 by cloning of the missing genes genR and genS

open access: yesMetabolic Engineering Communications, 2019
In pharmaceutical industry, isepamicin is mainly manufactured from gentamicin B, which is produced by Micromonospora echinospora as a minor component of the gentamicin complex.
Yingying Chang   +8 more
doaj   +1 more source

Pharmacodynamic Effects of Simulated Standard Doses of Antifungal Drugs against Aspergillus Species in a New In Vitro Pharmacokinetic/Pharmacodynamic Model [PDF]

open access: yes, 2011
In conventional MIC tests, fungi are exposed to constant drug concentrations, whereas in vivo, fungi are exposed to changing drug concentrations.
Thomas J. Walsh   +11 more
core   +1 more source

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