Results 31 to 40 of about 1,116,502 (236)

Identification and Elimination of Antifungal Tolerance in Candida auris

Biomedicines, 2023
Antimicrobial resistance is a global health crisis to which pathogenic fungi make a substantial contribution. The human fungal pathogen C. auris is of particular concern due to its rapid spread across the world and its evolution of multidrug resistance ...
Samira Rasouli Koohi, Shamanth A. Shankarnarayan, Clare Maristela Galon, Daniel A. Charlebois   +3 more
doaj   +1 more source

Susceptibilities of Malassezia strains from pityriasis versicolor, Malassezia folliculitis and seborrheic dermatitis to antifungal drugs

Heliyon, 2020
The human pathogenic yeast genus Malassezia may be an etiological agent of skin disorders and has received considerable attention from dermatologists in recent years.
Kaiqin Wang, Lu Cheng, Wenshuang Li, Hui Jiang, Xiaofang Zhang, Shanshan Liu, Yunli Huang, Mingyue Qiang, Tianxiang Dong, Yuye Li, Jin Wang, Shike Feng, Hongbin Li   +12 more
doaj   +1 more source

Evaluation of Antifungal Selective Toxicity Using Candida glabrata ERG25 and Human SC4MOL Knock-In Strains

Journal of Fungi, 2023
With only four classes of antifungal drugs available for the treatment of invasive systemic fungal infections, the number of resistant fungi is increasing, highlighting the urgent need for novel antifungal drugs.
Keiko Nakano, Michiyo Okamoto, Azusa Takahashi-Nakaguchi, Kaname Sasamoto, Masashi Yamaguchi, Hiroji Chibana   +5 more
doaj   +1 more source

Chemical Composition of Essential Oilsof Thymus and Mentha Speciesand Their Antifungal Activities [PDF]

, 2009
The potential antifungal effects of Thymus vulgaris L., Thymus tosevii L., Mentha spicata L., and Mentha piperita L. (Labiatae) essential oils and their components against 17 micromycetal food poisoning, plant, animal and human pathogens are presented ...
Marin, P.D., Petar D. Marin, Vlatka Vajs, Dejan D. Brkić, Marin, Petar D, Jelena Vukojević, Vajs, V., Vajs, Vlatka E, van Griensven, L.J.L.D., Marin, Petar D., Brkić, Dejan, Marin, Petar, Brkić, Dejan D, Leo J. L. D. Van Griensven, Van Griensven, Leo J. L. D., Leo J. L. D. van Griensven, Vukojević, J, Brkić, D D, Griensven, L.J.L.D., van, Dejan D. Brkić, van Griensven, Leo JLD, Jelena Vukojević, Vukojević, Jelena B., Van Griensven, Leo J.L.D., Vukojevic,, J., Vajs, Vlatka, Sokovic,, M.D., Marina D. Soković, Marina D. Soković, Soković, Marina, Vukojević, Jelena, Brkic, D.D.   +31 more
core   +1 more source

Medicines for Malaria Venture COVID Box: a source for repurposing drugs with antifungal activity against human pathogenic fungi

Memorias do Instituto Oswaldo Cruz, 2021
BACKGROUND Treatment of mycoses is often ineffective, usually prolonged, and has some side effects. These facts highlight the importance of discovering new molecules to treat fungal infections.
Rodrigo Almeida-Paes, Iara Bastos de Andrade, Mariana Lucy Mesquita Ramos, Marcus Vinícius de Araújo Rodrigues, Vinícius Alves do Nascimento, Andréa Reis Bernardes-Engemann, Susana Frases   +6 more
doaj   +1 more source

Introduction to Antifungal Drugs [PDF]

Clinical Infectious Diseases, 2000
In the United States, only 10 antifungal drugs are currently approved by the Food and Drug Administration (FDA) for the therapy of systemic fungal infections. As shown in table 1, these drugs belong to 3 principal classes: polyenes, pyrimidines, and azoles.
openaire   +2 more sources

The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin.

, 2023
The epidemiology of invasive fungal infections is changing, with new populations at risk and the emergence of resistance caused by the selective pressure from increased usage of antifungal agents in prophylaxis, empiric therapy, and agriculture.
Hoenigl, Martin, Egger, Matthias, Jenks, Jeffrey D, Spec, Andrej, Sprute, Rosanne, Lass-Flörl, Cornelia, Arastehfar, Amir, Krause, Robert, Thompson, George R, Prattes, Juergen, Wiederhold, Nathan, Cornely, Oliver A   +11 more
core   +1 more source

Novel Antifungal Compounds Discovered in Medicines for Malaria Venture’s Malaria Box

mSphere, 2018
Similarities in fungal and animal cells make antifungal discovery efforts more difficult than those for other classes of antimicrobial drugs. Currently, there are only three major classes of antifungal drugs used for the treatment of systemic fungal ...
Eric H. Jung, David J. Meyers, Jürgen Bosch, Arturo Casadevall   +3 more
doaj   +1 more source

Missed Opportunities for Antifungal Stewardship during the COVID-19 Era

Antibiotics, 2023
Significant increases in antibacterial use were observed during the COVID-19 pandemic. However, subsequent analyses found this increase in antibiotic use to be excessive in comparison with the relatively low rates of bacterial coinfection.
Brandon K. Hawkins, Samantha D. Walker, Mahmoud A. Shorman   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source