Synergistic antifungal effects and mechanisms of amantadine hydrochloride combined with azole antifungal drugs on drug-resistant Candida albicans [PDF]
Frontiers in Cellular and Infection MicrobiologyIntroductionThe increasing resistance of Candida albicans (C. albicans) to conventional antifungal drugs poses a great challenge to the clinical treatment of infections caused by this yeast.
Xiuyun Li +5 more
doaj +3 more sources
Invasive fungal infections in critically ill children: epidemiology, risk factors and antifungal drugs [PDF]
Drugs ContextBackground: Invasive fungal infections (IFIs) are important infectious complications amongst critically ill children. The most common fungal infections are due to Candida species.
Alexander KC Leung +4 more
core +2 more sources
ClinicoEconomics and Outcomes Research, 2015 Habip Gedik Department of Infectious Diseases and Clinical Microbiology, Ministry of Health Okmeydani Training and Research Hospital, Istanbul, Turkey Objective: The aim of this study is to analyze the expenditures related to the use of antifungal drugs
Gedik H
doaj +1 more source
Solid lipid nanoparticles, an effective carrier for classical antifungal drugs [PDF]
Saudi Pharm J, 2023 Solid-lipid nanoparticles (SLNs) are an innovative group of nanosystems used to deliver medicine to their respective targets with better efficiency and bioavailability in contrast to classical formulations.
Saud Almawash
core +2 more sources
Investigation of the antifungal activity of some non-antifungal drugs in clinical isolates of otomycosis: In vitro study [PDF]
مجلة علوم ذي قار, 2019 Otomycosis is one of the commonly encountered problems in otolaryngology practice. Treatment of otomycosis is challenging, and requires a close follow-up; in addition treatment with classical topical ...
Rana Muhsin, Rana Muhsin
doaj +7 more sources
An Aptamer-Based Biosensor for the Azole Class of Antifungal Drugs
mSphere, 2017 This technical report describes the development of an aptamer for sensing azole antifungal drugs during therapeutic drug monitoring. Modified synthetic evolution of ligands through exponential enrichment (SELEX) was used to discover a DNA aptamer ...
Gregory R. Wiedman +6 more
doaj +2 more sources
Chemometric Methods—A Valuable Tool for Investigating the Interactions Between Antifungal Drugs (Including Antifungal Antibiotics) and Food [PDF]
AntibioticsBackground/Objectives: Developing antifungal drugs with lower potential for interactions with food may help to optimize treatment and reduce the risk of antimicrobial resistance.
Agnieszka Wiesner-Kiełczewska +3 more
doaj +2 more sources
Molecular Docking-Based Screening of Five Heterocyclic Quinone Compounds for Antifungal Activity on Yeast Sec14p and Validation by Redocking [PDF]
Journal of Pharmaceutical ResearchDiscover new antifungal drugs by evaluating the efficacy of heterocyclic compounds. Investigate the potential of yeast Sec14p protein as a target for antifungal drugs.
Thomas Kurian
doaj +2 more sources
Frontiers in Pharmacology, 2022 Triazole antifungal drugs (TAD) are widely used to treat invasive fungal infections due to their broad antifungal spectrum and low toxicity. Despite their preference in the clinic, multiple Adverse Events (AE) are still reported each year.
Jianxing Zhou +8 more
doaj +1 more source
Antifungal Drug Repurposing [PDF]
Antibiotics, 2020 Control of fungal pathogens is increasingly problematic due to the limited number of effective drugs available for antifungal therapy. Conventional antifungal drugs could also trigger human cytotoxicity associated with the kidneys and liver, including the generation of reactive oxygen species.
Jong H. Kim +7 more
openaire +3 more sources