Results 111 to 120 of about 32,347 (265)

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Uncovering the connection between tunicamycin-induced respiratory deficiency and reduced fluconazole tolerance in Candida glabrata

Frontiers in Microbiology
IntroductionCandida glabrata is a prevalent opportunistic fungal pathogen in humans, and fluconazole (FLC) is one of the most commonly used antifungal agents. However, the molecular mechanisms underlying FLC tolerance in C.
Lijun Zheng, Yubo Dong, Jing Wang, Maoji Zhang, Yi Xu, Linfeng Ma, Liangsheng Guo   +6 more
doaj   +1 more source

Selective Oxidation Strategies for Cost‐Efficient Green Hydrogen Production via Hybrid Water Electrolysis

Carbon Energy, EarlyView.
Hybrid water electrolysis has emerged as a promising alternative to conventional electrolysis for sustainable hydrogen production. The economic potential of replacing water oxidation with organic substrates is assessed. For each substrate, representative electrocatalysts and mechanistic insights are reviewed to identify design principles for optimized ...
Conor Brennan‐Pollak, Lua Henderson, Cian Clarke, Maida A. Costa de Oliveira, Dídac A. Fenoll, Sreedhanya Pallilavalappil, Aswathy Babu, Shaista Jabeen, Pranav K. Gangadharan, Huabin Zhang, Suresh C. Pillai, Paula E. Colavita, Max García‐Melchor   +12 more
wiley   +1 more source

Echinocandin tolerance and persistence in vitro are regulated by calcineurin signaling in Candida glabrata

mBio
Upon exposure to echinocandins, growing yeast cells begin to accumulate cell wall damage and eventually die, resulting in therapeutic effects. While resistance to echinocandins is well studied, tolerance and persistence mechanisms that may also ...
Abigail A. Harrington, Timothy J. Nickels, Kyle W. Cunningham   +2 more
doaj   +1 more source

Cryptococcus neoformans Mar1 function links mitochondrial metabolism, oxidative stress, and antifungal tolerance. [PDF]

Front Physiol, 2023
Telzrow CL, Esher Righi S, Cathey JM, Granek JA, Alspaugh JA.   +4 more
europepmc   +1 more source

Trehalose metabolism and stress resistance in Aspergillus niger [PDF]

, 2013
Food spoilage by filamentous fungi, moulds, is a global issue of great significance. Mould growth can cause food losses due to deterioration, and adverse health effects due to toxin production.
Svanström, Åsa
core  

The interaction with fungal cell wall polysaccharides determines the salt tolerance of antifungal plant defensins

The Cell Surface, 2019
The fungal cell wall is the first point of contact between fungal pathogens and host organisms. It serves as a protective barrier against biotic and abiotic stresses and as a signal to the host that a fungal pathogen is present. The fungal cell wall is made predominantly of carbohydrates and glycoproteins, many of which serve as binding receptors for ...
Mark R. Bleackley, Charlotte S. Dawson, Jennifer A.E. Payne, Peta J. Harvey, K. Johan Rosengren, Pedro Quimbar, Donovan Garcia-Ceron, Rohan Lowe, Vincent Bulone, Nicole L. van der Weerden, David J. Craik, Marilyn A. Anderson   +11 more
openaire   +5 more sources

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Immunity and tolerance to fungi in hematopoietic transplantation: Principles and perspectives

Frontiers in Immunology, 2012
Resistance and tolerance are two complementary host defence mechanism that increase fitness in response to low-virulence fungi. Resistance is meant to reduce pathogen burden during infection through innate and adaptive immune mechanisms, whereas ...
Agostinho eCarvalho, Agostinho eCarvalho, Agostinho eCarvalho, Cristina eCunha, Silvia eBozza, Silvia eMoretti, Cristina eMassi-Benedetti, Francesco eBistoni, Franco eAversa, Luigina eRomani   +9 more
doaj   +1 more source

Versatile Palladium‐Catalyzed C‐H Arylation of Fluoroarenes with 2‐Chloropyridine Derivatives

Chemistry – A European Journal, EarlyView.
Direct C─H arylation of fluoroarenes with 2‐chloropyridines is enabled by a simple Pd/SPhos system in isopropyl acetate. The method uses inexpensive reactants and shows broad scope and high yields. DFT computations explain reactivity and selectivity.
Federico Belnome, Péter P. Fehér, András Stirling, Csongor G. Németh, Tamás Hergert, György M. Keserű, Péter Ábrányi‐Balogh   +6 more
wiley   +1 more source