Results 21 to 30 of about 1,150,155 (343)

Assessment of serum selenium and ceruloplasmin in potentially malignant disorders and oral cancer

Journal of Pharmacy and Bioallied Sciences, 2021
Introduction: Despite extensive research and development, potentially malignant disorders (PMDs) of the oral cavity and oral cancer remain a serious concern.
Mathew O Mampilly, Nidhi Ravindran, Mohamed Shajith Parambil, Kumar Nilesh, Parvathi Jayagopalan, Debjit Dhamali   +5 more
doaj   +1 more source

In Silico Methods in Antibody Design

Antibodies, 2018
Antibody therapies with high efficiency and low toxicity are becoming one of the major approaches in antibody therapeutics. Based on high-throughput sequencing and increasing experimental structures of antibodies/antibody-antigen complexes, computational
Jun Zhao, Ruth Nussinov, Wen-Jin Wu, Buyong Ma   +3 more
doaj   +1 more source

Probing Molecular Interactions in Intact Antibody: Antigen Complexes, an Electrospray Time-of-Flight Mass Spectrometry Approach [PDF]

, 2001
Using a combination of nanoflow-electrospray ionization and time-of-flight mass spectrometry we have analyzed the oligomeric state of the recombinant V antigen from Yersinia pestis, the causative agent of plague.
Despeyroux-Hill, Dominique, Griffin, Kate F., Miller, Julie, Robinson, Carol V., Titball, Richard W., Tito, Mark A., Walker, Nicola, Williamson, E. Diane   +7 more
core   +1 more source

The Modified Vaccination Technique

Vaccines, 2018
In addition to active and passive immunizations, there is a third method of immunization, the modified vaccination technique, which is based on injecting a combination of target antigens and antibodies against this antigen.
Arpad Barabas, Chad Cole, Zoltan Kovacs, Erno Kovacs, Rene Lafreniere   +4 more
doaj   +1 more source

A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen. [PDF]

, 2018
Anti-carbohydrate monoclonal antibodies (mAbs) hold great promise as cancer therapeutics and diagnostics. However, their specificity can be mixed, and detailed characterization is problematic, because antibody-glycan complexes are challenging to ...
Amon, Ron, Chen, Xi, Fleishman, Sarel J, Glushka, John N, Grant, Oliver C, Leviatan Ben-Arye, Shani, Makeneni, Spandana, Marshanski, Tal, Nivedha, Anita K, Norn, Christoffer, Padler-Karavani, Vered, Woods, Robert J, Yu, Hai   +12 more
core   +2 more sources

Isolation of Circulating Immune Complexes from TB Patient Serum for Serodiagnosis

Bio-Protocol, 2012
Estimation of circulating immune complex in tuberculosis patients has shown better insight to the infection. Isolating circulating immune complex helps quantifying both antigen and antibody in the serum. It’s a simple procedure to improve the sensitivity
Uma Ranganathan, Ramalingam Bethunaickan, Alamelu Raja   +2 more
doaj   +1 more source

Current Status of Autoimmune Hepatitis in Japan [PDF]

, 2008
Autoimmune hepatitis (AIH) is a chronic and progressive disease characterized by histological interface hepatitis, hypergammaglobulinemia, and circulating autoantibodies. Multiple factors, including molecular mimicry, a genetic background including major
Miyake, Yasuhiro, Yamamoto, Kazuhide
core   +1 more source

Molecular epitope identification by limited proteolysis of an immobilized antigen-antibody complex and mass spectrometric peptide mapping.

Proceedings of the National Academy of Sciences of the United States of America, 1990
Sequences of antigenic determinants were identified by limited proteolysis of peptide antigens bound to an immobilized monoclonal antibody and direct molecular weight determination of the monoclonal antibody-bound peptide fragments by 252Cf plasma ...
D. Suckau, Jorg KOHLt, Gabriele KARWATHt, K. Schneider, Monika CASARETTOt, Dieter BITTER-SUERMANNt, M. Przybylski   +6 more
semanticscholar   +1 more source

T-cell Epitopes of Mycobacterium tuberculosis Antigen 85 Complex Potential for Generating Antibody: an Immunoinformatics Study

Microbiology Indonesia, 2010
The present study was conducted to predict T-cell epitopes of the antigen 85 complex capable of stimulating antibody generation by using immunoinformatics approaches.
YOGY SIMANJUNTAK
doaj   +1 more source

Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targeting Viral gH/gL/pUL128-131 Pentameric Complex [PDF]

, 2017
Human cytomegalovirus (HCMV) is the leading cause of congenital viral infection, and developing a prophylactic vaccine is of high priority to public health.
Adler, Stuart P., An, Zhiqiang, DePhillips, Pete A., Freed, Daniel C., Fu, Tong-Ming, Ha, Sha, Hamm, Melissa, Li, Fengsheng, Loughney, John W., McLellan, Jason S., McVoy, Michael A., Nickle, David C., Rustandi, Richard R., Tang, Aimin, Troutman, Matthew C., Vlasak, Josef, Wang, Dai, Wang, I-Ming, Zhang, Ningyan, Zhu, Hua   +19 more
core   +3 more sources