Results 111 to 120 of about 497,334 (328)

Correlations in the T Cell Response to Altered Peptide Ligands

open access: yes, 2004
The vertebrate immune system is a wonder of modern evolution. Occasionally, however, correlations within the immune system lead to inappropriate recruitment of preexisting T cells against novel viral diseases.
Arstila   +26 more
core   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Diverse Epitope Specificity, Immunodominance Hierarchy, and Functional Avidity of Effector CD4 T Cells Established During Priming Is Maintained in Lung After Influenza A Virus Infection

open access: yesFrontiers in Immunology, 2018
One of the major contributions to protective immunity to influenza viruses that is provided by virus-specific CD4 T cells is delivery of effector function to the infected lung.
Katherine A. Richards   +6 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Dr. Jekyll and Mr. Hyde - Distinctiveness and plasticity of mononuclear phagocytes in the mouse skin [PDF]

open access: yes, 2008
Antigen-presenting cells are crucial participants in the defense of the body against potentially pathogenic invaders. In an immature state, they reside in all peripheral sites, where they can recognize and take up antigens.
Dupasquier, M. (Marcel)
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Immunohistochemical analysis of Langerhans cells in chronic gingivitis using anti-CD1a antibody

open access: yesDental Research Journal, 2014
Background: The Langerhans cells (LCs) are dendritic cells (DCs) which belong to the group of antigen presenting cells (APCs). Their function is to recognize the antigen, capture it, and present it to the T lymphocytes; thus initiating an early immune ...
Shweta Jaitley   +3 more
doaj  

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