Results 151 to 160 of about 505,925 (298)

Antigen presentation by B cells [PDF]

Nature, 1989
K, Bottomly, C A, Janeway
openaire   +2 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Oral Celastrol Nanomedicine Targeting Intestinal Antigen-Presenting Cells to Effectively Mitigate Autoimmune Uveitis via Gut-Retina Axis. [PDF]

Adv Sci (Weinh)
Chen J, Wu Y, Xu B, Hou J, Li Y, Hu Y, Zhu Y, Zhang W, Feng S, Jin H, Cheng Y, Jin Y, Zhou J, Li X.   +13 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus. [PDF]

Sci Transl Med
Younis S, Moutusy SI, Rasouli S, Jahanbani S, Pandit M, Wu X, Acharya S, Sharpe O, Wijeratne TU, Harris ML, Yang EY, Chaichian Y, Parsafar S, Baker MC, Harley JB, Meffre E, Steinman L, Marshak-Rothstein A, James JA, Martinez OM, Utz PJ, Orange DE, Lanz TV, Robinson WH.   +23 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The Role of Retinal Antigen-Presenting Cells in Spontaneous Retinal Autoimmunity. [PDF]

Invest Ophthalmol Vis Sci
Sherman J, Burgstaler L, Li Y, Roehrich H, Gregerson DS, McPherson SW.   +5 more
europepmc   +1 more source

Phenotypic and functional differences of dendritic cells generated under different in vitro conditions [PDF]

, 2003
Ali, SA, Li, G, McArdle, SE, Mian, S, Rees, RC   +4 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

B cells maintain the homeostasis of splenic marginal zone antigen-presenting cells to promote the antiviral CD8⁺ T-cell response. [PDF]

Cell Mol Immunol
Liu X, Demircik F, Antipova M, Stylianakis E, Klein M, Bejarano D, Elwy A, Ebering A, Blanfeld M, Carter K, Johann L, Uhlfelder DC, Blickberndt E, Chen Y, Probst HC, Hövelmeyer N, Bopp T, Arens R, Bunse L, den Haan JMM, Gommerman JL, von Stebut E, Clausen BE, Schlitzer A, Lang KS, Su B, Backer RA, Lemmermann NA, Waisman A.   +28 more
europepmc   +1 more source