Results 261 to 270 of about 500,224 (304)

Antigen presentation, antigen-presenting cells and antigen processing

Current Opinion in Immunology, 1988
To summarize, during the period under review there have been considerable advances in our understanding of how antigen is associated with MHC on the surface of a presenting cell. Basic rules which govern this association have been confirmed as including both the nature and the configuration of the antigen.
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Antigen-presenting cells in allergy

Journal of Allergy and Clinical Immunology, 2001
The complex interaction of the innate and adaptive immune system requires flexibility and cooperation among various cell types. In this regard, antigen-presenting-cells (APCs) play a pivotal role in transferring information from the periphery of the organism to lymphoid organs, where they initiate the activation of naive T cells.
D, von Bubnoff, E, Geiger, T, Bieber
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Cell biology of antigen presentation

Current Opinion in Immunology, 1993
MHC class I molecules present degradation products derived from intracellular proteins, whereas MHC class II molecules generally present peptides derived from extracellular or surface proteins. Recent insights into the cell biology of MHC class I and II molecules explain this difference.
J J, Neefjes, F, Momburg
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Corneal Antigen-Presenting Cells

2007
Corneal antigen-presenting cells (APCs) were thought to reside exclusively in the peripheral cornea. However, recent evidence demonstrates that the central cornea is also endowed with a heterogeneous population of bone marrow-derived cells, including epithelial Langerhans cells (LCs) and anterior stromal dendritic cells (DCs), which under certain ...
Pedram, Hamrah, M Reza, Dana
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Epithelial cell antigen presentation

Current Opinion in Gastroenterology, 2000
For decades intestinal epithelial cells were thought of as passive barriers to luminal contents, cells involved in nutrient absorption and electrolyte secretion. Studies during the past 10 to 15 years have changed that concept as our understanding of mucosal immunity has evolved and as we have come to understand that the regulation of this system is ...
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T cells as antigen-presenting cells

Immunology Today, 1994
Human T cells express major histocompatibility complex (MHC) class II antigens and adhesion molecules characteristic of antigen-presenting cells (APCs), and recent in vitro and in vivo evidence supports an antigen-presenting function for T cells. In this guise, T cells provide downregulatory signals for the immune response by inducing anergy in T cells
Pichler WJ, Wyss-Coray T
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Are the Mast Cells Antigen Presenting Cells?

Immunological Investigations, 1989
Mast cells have an important role in allergic reactions secreting histamine and other mediators of immediate hypersensitivity. In the present study we evaluated major histocompatibility complex (MHC) class II antigen expression in mast cells and their possible role in antigen presentation.
K, Banovac, D, Neylan, J, Leone, L, Ghandur-Mnaymneh, A, Rabinovitch   +4 more
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Antigen presentation to B cells

Current Opinion in Immunology, 1991
B lymphocytes encounter antigen within the body, which causes them to undergo clonal expansion, affinity maturation and differentiation to antibody-forming cells. How they come into contact with the immunogen, and the subsequent response induced is the subject of several recent reports.
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Antigen presenting cells and mechanisms of antigen presentation.

Critical reviews in immunology, 1985
In this review we will examine the characteristics of the various cell types which have been shown to present antigens to helper and proliferating T cells and explore what is known about the requirements for antigen presentation by these cells. Cell types to be discussed include mononuclear phagocytes from a variety of tissues as well as nonphagocytic ...
R W, Chesnut, H M, Grey
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B cells as antigen presenting cells

Cellular Immunology, 2005
Several characteristics confer on B cells the ability to present antigen efficiently: (1) they can find T cells in secondary lymphoid organs shortly after antigen entrance, (2) BCR-mediated endocytosis allows them to concentrate small amounts of specific antigen, and (3) BCR signaling and HLA-DO expression direct their antigen processing machinery to ...
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