Results 21 to 30 of about 6,214,641 (266)
International Journal of Nanomedicine, 2017 Jie Gao,1–3 Lukasz J Ochyl,1,3 Ellen Yang,4 James J Moon1,3,5 1Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA; 2Department of Pharmaceutical Sciences, School of Pharmacy, Second Military Medical University ...
Gao J, Ochyl LJ, Yang E, Moon JJ
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Activated Brain Endothelial Cells Cross-Present Malaria Antigen. [PDF]
PLoS Pathogens, 2015 In the murine model of cerebral malaria caused by P. berghei ANKA (PbA), parasite-specific CD8+ T cells directly induce pathology and have long been hypothesized to kill brain endothelial cells that have internalized PbA antigen.
Shanshan W Howland +2 more
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International Journal of Nanomedicine, 2016 Chanyoung Song,* Young-Woock Noh,* Yong Taik Lim SKKU Advanced Institute of Nanotechnology (SAINT), School of Chemical Engineering, Sungkyunkwan University, Suwon, South Korea *These authors contributed equally to this work Abstract: Effective ...
Song C, Noh YW, Lim YT
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Cell Rep, 2022 Despite its crucial role in initiation of cytotoxic immune responses, the molecular pathways underlying antigen cross-presentation remain incompletely understood.
Gros M +13 more
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Antigen Presentation in the Lung
Frontiers in Immunology, 2022 The lungs are constantly exposed to environmental and infectious agents such as dust, viruses, fungi, and bacteria that invade the lungs upon breathing. The lungs are equipped with an immune defense mechanism that involves a wide variety of immunological
Takumi Kawasaki, Moe Ikegawa, Taro Kawai
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Molecular and cell-biological mechanisms of antigen cross-presentation [PDF]
Frontiers in Immunology, 2013 Cross-priming serves to activate cytotoxic T lymphocytes for immune defense against viruses and tumors and plays an important role in vaccinations. Only certain dendritic cell (DC) subsets can cross-present. Several cell surface markers have been described that more or less specifically and sensitively characterize these subsets.
Christian eKurts
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Endo-lysosomal assembly variations among human leukocyte antigen class I (HLA class I) allotypes
eLife, 2023 The extreme polymorphisms of human leukocyte antigen class I (HLA class I) proteins enable the presentation of diverse peptides to cytotoxic T lymphocytes.
Eli Olson +2 more
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Frontiers in Immunology, 2023 CD8 T cells are important antiviral effectors in the adaptive immune response to cytomegaloviruses (CMV). Naïve CD8 T cells can be primed by professional antigen-presenting cells (pAPCs) alternatively by “direct antigen presentation” or “antigen cross ...
Julia K. Büttner +8 more
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Proteasomal degradation within endocytic organelles mediates antigen cross‐presentation [PDF]
EMBO Journal, 2019 Xinran Liu +2 more
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Application of Antigen Cross-Presentation Research into Patient Care [PDF]
Frontiers in Immunology, 2014 Dendritic cell (DC)-based cellular immunotherapy is being explored as a treatment modality for several malignancies, for viral diseases and auto-immune disorders. More than four decades of pre-clinical research on DC biology has cemented a strong foundation for clinical application of DC-based clinical trials, which already have been performed since ...
Flinsenberg, Thijs W. H., Boes, Marianne
openaire +3 more sources