Bovine Derived in vitro Cultures Generate Heterogeneous Populations of Antigen Presenting Cells
Antigen presenting cells (APC) of the mononuclear phagocytic system include dendritic cells (DCs) and macrophages (Macs) which are essential mediators of innate and adaptive immune responses.
Efrain Guzman +4 more
doaj +1 more source
Immune cell activation is essential for cancer rejection; however, the tumor microenvironment leads to deterioration of immune function, which enables cancer cells to survive and proliferate. We previously reported that oral ingestion of Lentinula Edodes
Shota Kajiyama +6 more
doaj +1 more source
Antigen presentation to B cells [PDF]
B cells are capable of mounting responses to a bewildering range of potentially pathogenic antigens through the production of high-affinity antibodies and the establishment of immunological memory. Thus, regulated B-cell activation is critical for protection against a variety of bacterial and viral infections, as well as cancers.
Harwood, Naomi E, Batista, Facundo D
openaire +2 more sources
Studies on the role of cholesterol and coronin 1 in antigen-presenting cells [PDF]
Antigen recognition and presentation to subsequently induce an appropriate host response is dependent on the action of antigen-presenting cells such as dendritic cells and macrophages.
Albrecht, Imke
core +1 more source
Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells. [PDF]
Infection of the mammalian host by the parasitic helminth Schistosoma mansoni is accompanied by the release of excretory/secretory molecules (ES) from cercariae which aid penetration of the skin.
Ross A Paveley +20 more
core +1 more source
Conditional immortalization of human B cells by CD40 ligation [PDF]
It is generally assumed that human differentiated cells have a limited life-span and proliferation capacity in vivo, and that genetic modifications are a prerequisite for their immortalization in vitro.
Mayr, C. +27 more
core +1 more source
Impact of Gold Nanoparticles on the Functions of Macrophages and Dendritic Cells
Gold nanoparticles (AuNPs) have demonstrated outstanding performance in many biomedical applications. Their safety is recognised; however, their effects on the immune system remain ill defined. Antigen-presenting cells (APCs) are immune cells specialised
Arindam K. Dey +5 more
doaj +1 more source
Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells [PDF]
Interactions between antigen-presenting dendritic cells (DCs) and T cells are essential for the induction of an immune response. However, during malaria infection, DC function is compromised and immune responses against parasite and heterologous antigens
Owain R Millington +34 more
core +1 more source
The Antigen Presenting Cells Instruct Plasma Cell Differentiation
The professional antigen presenting cells (APCs), including many subsets of dendritic cells and macrophages, not only mediate prompt but nonspecific response against microbes, but also bridge the antigen-specific adaptive immune response through antigen ...
Wei eXu, Jacques eBanchereau
doaj +1 more source
Recent Advances in Nanovaccines Using Biomimetic Immunomodulatory Materials
The development of vaccines plays a vital role in the effective control of several fatal diseases. However, effective prophylactic and therapeutic vaccines have yet to be developed for completely curing deadly diseases, such as cancer, malaria, HIV, and ...
Veena Vijayan +3 more
doaj +1 more source

