Results 21 to 30 of about 368,728 (306)

Tumor Antigen Presentation by Dermal Antigen-Presenting Cells [PDF]

Journal of Investigative Dermatology, 2000
Several phenotypes of antigen-presenting cells are present in the dermis, where they presumably function to present encountered antigens for immune responses. This study examined the ability of dermal antigen-presenting cells to present tumor-associated antigens for the induction of in vivo antitumor immunity.
Campton, Kristina, Ding, Wanhong, Yan, Zengmin, Ozawa, Hiroaki, Seiffert, Kristina, Miranda, Edward, Granstein, Richard D., Lonati, Antonietta, Beissert, Stefan   +8 more
openaire   +2 more sources

Daratumumab prevents programmed death ligand‐1 expression on antigen‐presenting cells in de novo multiple myeloma

Cancer Medicine, 2020
Background Daratumumab (Dara), an anti‐CD38 monoclonal antibody, has an immunologic mechanism of action through targeting of CD38 expressing immune cells in patients with multiple myeloma (MM). Furthermore, it was recently shown that CD38 upregulation in
Nicolas Stocker, Béatrice Gaugler, Laure Ricard, Frédéric deVassoigne, Zora Marjanovic, Mohamad Mohty, Florent Malard   +6 more
doaj   +1 more source

Antigen presentation by Langerhans cells [PDF]

Current Opinion in Immunology, 2013
Langerhans cells and other skin-resident dendritic cells (DC) are required for the development of cutaneous adaptive immune responses. In vivo experiments using mice with selective DC-subset deficiencies and ex vivo experiments using isolated DC suggests that each subset makes a unique contribution to the adaptive response.
Botond Z, Igyártó, Daniel H, Kaplan
openaire   +2 more sources

Viscoelastic synthetic antigen-presenting cells for augmenting the potency of cancer therapies [PDF]

Nature Biomedical Engineering
Yichen Zhu, Tyler Hoffman, Enbo Zhu
exaly   +2 more sources

The ABCs of Antigen Presentation by Stromal Non-Professional Antigen-Presenting Cells [PDF]

International Journal of Molecular Sciences, 2021
Professional antigen-presenting cells (APCs), such as dendritic cells and macrophages, are known for their ability to present exogenous antigens to T cells. However, many other cell types, including endothelial cells, fibroblasts, and lymph node stromal cells, are also capable of presenting exogenous antigens to either CD8+ or CD4+ T cells via cross ...
Tom J. Harryvan, Sabine de Lange, Lukas J.A.C. Hawinkels, Els M.E. Verdegaal   +3 more
openaire   +3 more sources

Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus

Microbiome, 2023
Background Cervicovaginal inflammation has been linked to negative reproductive health outcomes including the acquisition of HIV, other sexually transmitted infections, and cervical carcinogenesis. While changes to the vaginal microbiome have been linked
Christina Farr Zuend, Alana Lamont, Laura Noel-Romas, Samantha Knodel, Kenzie Birse, Kateryna Kratzer, Peter McQueen, Michelle Perner, Hossaena Ayele, Sarah Mutch, Alicia R. Berard, John J. Schellenberg, Faruk Senturk, Stuart McCorrister, Garrett Westmacott, Fran Mulhall, Bonnie Sandberg, Adelicia Yu, Margaret Burnett, Vanessa Poliquin, Adam D. Burgener   +20 more
doaj   +1 more source

Antigen presentation and T cell regulation by intestinal epithelial cells

, 2022
Major histocompatibility complex (MHC) class II expression by intestinal epithelial cells (IECs) has been described in inflammatory bowel disease patients.
Heuberger, Cornelia
core   +1 more source

Recent Advances in Experimental Dendritic Cell Vaccines for Cancer

Frontiers in Oncology, 2021
The development of immunotherapeutic methods for the treatment of oncological diseases have made it possible to improve the effectiveness of standard therapies.
Ivan Y. Filin, Kristina V. Kitaeva, Catrin S. Rutland, Albert A. Rizvanov, Valeriya V. Solovyeva   +4 more
doaj   +1 more source

Antigen Presentation by Vascular Cells [PDF]

Frontiers in Immunology, 2017
Antigen presentation by cells of the vessel wall may initiate rapid and localized memory immune responses in peripheral tissues. Peptide antigens displayed on major histocompatibility complex (MHC) molecules on the surface of endothelial cells (ECs) can be recognized by T cell receptors on circulating effector memory T cells (TEM), triggering both ...
Jordan S. Pober, Jonathan Merola, Rebecca Liu, Thomas D. Manes   +3 more
openaire   +3 more sources

The potential role of T-cells and their interaction with antigen-presenting cells in mediating immunosuppression following trauma-hemorrhage [PDF]

, 2009
Objective: Trauma-hemorrhage results in depressed immune responses of antigen-presenting cells (APCs) and T-cells. Recent studies suggest a key role of depressed T-cell derived interferon (IFN)-g in this complex immune cell interaction.
Loehe, Florian, Chaudry, Irshad H., Christian R. Walz, Christiane J. Bruns, Walz, Christian, Bruns, Christiane J., Irshad H. Chaudry, Eugen Faist, Faist, Eugen, Schneider, Christian P., Siegfried Zedler, Christian P. Schneider, Martin K. Angele, Markus Albertsmeier, Angele, Martin K., Zedler, Siegfried, Florian Loehe, Albertsmeier, Markus   +17 more
core   +1 more source