Engineered artificial antigen-presenting cells for tumor immunotherapy: Design strategies, clinical applications, and translational challenges [PDF]
Materials Today BioImmunotherapy has long played a pivotal role in cancer treatment, and antigen-presenting cell (APC)-based immunotherapy represents a promising strategy, though its full potential remains to be realized.
Haojie Cai +11 more
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Characterisation of antigen-presenting cells in the murine female reproductive tract and its draining lymph nodes [PDF]
, 2011 Despite the global burden of sexually transmitted diseases, the immunology of the female reproductive tract is poorly understood. An understanding of how the distribution of antigen presenting cells in the tissue and cross talk between cell types both ...
Roche, Rebecca
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Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform [PDF]
Drug DeliveryDelivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy.
Barnabas Nyesiga +6 more
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Microsomal membranes from antigen presenting cells present antigenic peptides to T cells: a novel approach in vaccine development. [PDF]
, 2010 PhDThe study of the immune system has provided insight in the mechanism of protection induced by vaccination; primarily that most clinically protective vaccines are potent in generating neutralizing antibody responses.
Sofra, Vasiliki
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Antigen presentation and T cell regulation by intestinal epithelial cells [PDF]
, 2022 Major histocompatibility complex (MHC) class II expression by intestinal epithelial cells (IECs) has been described in inflammatory bowel disease patients.
Heuberger, Cornelia
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Recent Advances in Experimental Dendritic Cell Vaccines for Cancer
Frontiers in Oncology, 2021 The development of immunotherapeutic methods for the treatment of oncological diseases have made it possible to improve the effectiveness of standard therapies.
Ivan Y. Filin +4 more
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The potential role of T-cells and their interaction with antigen-presenting cells in mediating immunosuppression following trauma-hemorrhage [PDF]
, 2009 Objective: Trauma-hemorrhage results in depressed immune responses of antigen-presenting cells (APCs) and T-cells. Recent studies suggest a key role of depressed T-cell derived interferon (IFN)-g in this complex immune cell interaction.
Loehe, Florian +17 more
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Bovine Derived in vitro Cultures Generate Heterogeneous Populations of Antigen Presenting Cells
Frontiers in Immunology, 2019 Antigen presenting cells (APC) of the mononuclear phagocytic system include dendritic cells (DCs) and macrophages (Macs) which are essential mediators of innate and adaptive immune responses.
Efrain Guzman +4 more
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NanoAPC deliver antigen, IL-2 and co-stimulatory molecules to antigen specific T cells and activate viral specific T cells in chronic infections [PDF]
, 2011 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The study of the immune system has provided insight in the mechanism of protection induced by vaccination; primarily that most clinically protective ...
Liu, Mengya
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BMC Complementary Medicine and Therapies, 2023 Immune cell activation is essential for cancer rejection; however, the tumor microenvironment leads to deterioration of immune function, which enables cancer cells to survive and proliferate. We previously reported that oral ingestion of Lentinula Edodes
Shota Kajiyama +6 more
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