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Antigen processing and presentation
Immunology Letters, 1990An overview of the various aspects of antigen degradation and presentation is given with special emphasis on the possible occurrence of variation in the enzymatic machinery present in different cells or individuals. Different procedures for epitope mapping are also presented as well as the characterization of universal epitopes in humans.
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Antigen presentation, antigen-presenting cells and antigen processing
Current Opinion in Immunology, 1988To summarize, during the period under review there have been considerable advances in our understanding of how antigen is associated with MHC on the surface of a presenting cell. Basic rules which govern this association have been confirmed as including both the nature and the configuration of the antigen.
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Endosomal proteases and antigen processing
Trends in Biochemical Sciences, 1997T cells are activated by fragments of antigenic proteins bound to major histocompatibility complex (MHC) molecules and displayed on the cell surface. MHC class II proteins scavenge processed protein antigens from within endosomal compartments. The antigenic peptides are generated within these and other intracellular compartments using the array of ...
B, Fineschi, J, Miller
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Antigen processing and presentation in transplantation
Current Opinion in Immunology, 1996For many years the direct stimulation of T cells in response to donor MHC antigens expressed on donor antigen-presenting cells has been the focus of transplantation immunology. Indirect recognition in response to peptides of donor antigens presented by self MHC molecules on recipient antigen-presenting cells has not generally been considered an ...
H, Auchincloss, H, Sultan
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Lymphatics and the processing of antigen
Clinics in Dermatology, 1995T J, Ryan, E C, Mallon
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Perspective on antigen processing and presentation
Immunological Reviews, 2002Summary: The phenomenon of antigen processing and presentation and the concept that T cells recognize peptides resulting from the partial catabolism of proteins, are relatively new. These concepts were first recognized and developed at a time when lymphocyte immunity − the adaptive system – and cellular immunity, with its major component of activated ...
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Antigen processing and recognition
Current Opinion in Immunology, 2007Peter, van Endert, José A, Villadangos
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Antigen processing movers and shakers
Nature Chemical Biology, 2018Monitoring MHC-I dynamics upon binding to its chaperone TAPBPR helps us understand how optimal peptide sequences are selected for presentation and coordinated with release of the chaperone from the ternary peptide–MHC-I–TAPBPR complex.
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