Results 31 to 40 of about 122,331 (271)

Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine [PDF]

, 2014
Swine influenza A virus is an endemic and economically important pathogen in pigs, with the potential to infect other host species. The hemagglutinin (HA) protein is the primary target of protective immune responses and the major component in swine ...
A. L. Vincent, Anderson, Bao, Bowman, Brown, Centers for Disease Control and Prevention, Core Team R, D. F. Burke, Darriba, De Jong, E. Skepner, Edgar, Feng, Fouchier, Garten, Gauger, Harmon, Hinshaw, Houser, Karasin, Kawaoka, Khurana, Kitikoon, Koel, Lewis, Lindstrom, Lorusso, Loving, Maddison, Miller, Montalvao, Myers, N. S. Lewis, Nelson, Nelson, Nfon, Olsen, P. Kitikoon, Paradis, Pena, Polewicz, PyMOL, Röhm, Salmon, Shinde, Skowronski, Smith, Smith, Stamatakis, T. K. Anderson, Tong, Tong, Vincent, Vincent, Vincent, Vincent, Webby, Webby, Ye   +58 more
core   +2 more sources

Interference of infectious bursal disease virus on antibody production against Newcastle disease and infectious bronchitis virus

Brazilian Journal of Poultry Science, 2006
This work has the objective of verifying the interference of infectious bursal disease virus in the antibody production against Newcastle disease virus and infectious bronchitis virus.
WM Cardoso, JLC Aguiar Filho, JM Romão, RPR Salles, SR Câmara, AA Siqueira, WF Oliveira, MHNR Sobral, RSC Texeira   +8 more
doaj   +1 more source

COLONOSCOPY AND CARCINOEMBRYONIC ANTIGEN VARIATIONS [PDF]

Arquivos de Gastroenterologia, 2014
Context Colonoscopy is essential for synchronous and metachronous cancer detection. Carcinoembryonic antigen is a colorectal cancer tumor marker, important as a follow-up tool in patients with previous colorectal cancer. False-positive carcinoembryonic antigen elevation results in multiples exams and in patient anxiety.
SOUSA, Rita G, NUNES, Ana, MEIRA, Tânia, CARREIRA, Olga, PIRES, Ana M, FREITAS, João   +5 more
openaire   +4 more sources

Distinct, developmental stage-specific activation mechanisms of trypanosome VSG genes [PDF]

, 1990
The metacyclic form of African trypanosomes is the first to express genes for the Variant Surface Glycoprotein (VSG) and it uses an unusually predictable subset of the VSG gene repertoire.
Barry, J D, Graham, S V, Matthews, K R, Shiels, P G   +3 more
core   +1 more source

Deconvolving mutational patterns of poliovirus outbreaks reveals its intrinsic fitness landscape. [PDF]

, 2020
Vaccination has essentially eradicated poliovirus. Yet, its mutation rate is higher than that of viruses like HIV, for which no effective vaccine exists.
Barton, John P, Chakraborty, Arup K, McKay, Matthew R, Quadeer, Ahmed A   +3 more
core   +3 more sources

The effects of symmetry on the dynamics of antigenic variation

, 2012
In the studies of dynamics of pathogens and their interactions with a host immune system, an important role is played by the structure of antigenic variants associated with a pathogen.
A Fässler, A Marcello, B Adams, B Fiedler, C Jones, C Newbold, C Stockdale, CA Pinto, CMR Turner, CO Buckee, CO Buckee, DG Aronson, DJ Smith, DL Martin, H Farkas, I Stewart, IM Rouzine, JD Barry, JD Murray, JHP Dawes, JL Mitchell, JL Muñoz-Jordán, JR Gog, JW Swift, KA Lythgoe, KB Blyuss, Konstantin B. Blyuss, KW Deitsch, LJ Abu-Raddad, LM Pecora, M Dellnitz, M Golubitsky, M Golubitsky, M Golubitsky, M Golubitsky, M Recker, M Recker, M Recker, M Recker, M Recker, MGM Gomes, MJ Gardner, O Bagasra, P Ashwin, P Ashwin, P Borst, P De Leenheer, P Hagblom, P Minaev, PL Buono, R Antia, S Gupta, S Gupta, S Gupta, S Kyes, S Lutenschlager, SA Frank, SA Frank, SH Strogatz, V Calvez, Y Jiang, Z Agur   +61 more
core   +1 more source

Rapid turnover of Plasmodium falciparum var gene transcripts and genotypes during natural non-symptomatic infections Rápida mudança de transcritos var e de génotipos de Plasmodium falciparum em infecções assintomáticas naturalmente adquiridas

Revista do Instituto de Medicina Tropical de São Paulo, 2005
The var genes of Plasmodium falciparum code for the antigenically variant erythrocyte membrane proteins 1 (PfEMP1), a major factor for cytoadherence and immune escape of the parasite.
Gerhard Wunderlich, Fabiana P. Alves, Uta Gölnitz, Mauro S. Tada, Erney F.P. de Camargo, Luiz H. Pereira-da-Silva   +5 more
doaj   +1 more source

Influenza A virus hemagglutinin antibody escape promotes neuraminidase antigenic variation and drug resistance. [PDF]

PLoS ONE, 2011
Drugs inhibiting the influenza A virus (IAV) neuraminidase (NA) are the cornerstone of anti-IAV chemotherapy and prophylaxis in man. Drug-resistant mutations in NA arise frequently in human isolates, limiting the therapeutic application of NA inhibitors.
Scott E Hensley, Suman R Das, James S Gibbs, Adam L Bailey, Loren M Schmidt, Jack R Bennink, Jonathan W Yewdell   +6 more
doaj   +1 more source

African Trypanosomes undermine humoral responses and vaccine development : link with inflammatory responses? [PDF]

, 2017
African trypanosomosis is a debilitating disease of great medical and socioeconomical importance. It is caused by strictly extracellular protozoan parasites capable of infecting all vertebrate classes including human, livestock, and game animals.
Achcar, Alampour-Rajabi, Alirol, Allman, Authie, Authié, Auty, Baker, Balber, Banks, Barry, Barry, Berthier, Beschin, Beschin, Blom-Potar, Bockstal, Bockstal, Boller, Bonnet, Borst, Bosschaerts, Boulange, Bouyer, Brun, Brun, Bucheton, Calandra, Capewell, Chamond, Claes, Cnops, Cnops, Cnops, Cnops, Coller, Dagenais, Darji, De Muylder, De Trez, Delafosse, Delespaux, Desquesnes, Devine, Disease, Drennan, Dubois, Duszenko, Engstler, Fenn, Ferrante, Field, Figarella, Franco, Frenkel, Gilbert, Giordani, Gomez-Rodriguez, Graham, Graham, Haanstra, Hall, Hasker, Hemphill, Holland, Holland, Holt, Jamonneau, Jarvinen, Jones, Keitany, Kennedy, Kennedy, Klasen, Kondo, Kroubi, Kuriakose, La Greca, La Greca, Lalmanach, Lanca, Lebien, Lejon, Lejon, Leng, MacGregor, MacGregor, MacLean, MacLean, Magez, Magez, Magez, Mansfield, McGettrick, Mekori, Millar, Mogk, Mony, Morrison, Morrison, Morrison, Mulindwa, Mårtensson, Naessens, Naula, Ng, Nutt, Obishakin, Odongo, Onyilagha, Ooi, Ooi, Osório, O’Gorman, Paulnock, Pays, Peacock, Priotto, Radwanska, Radwanska, Reth, Rico, Rodgers, Rotureau, Ruiz-Postigo, Salmon, Schwede, Schwede, Seed, Sharpe, Sileghem, Sileghem, Simarro, Simarro, Simarro, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Swallow, Takeya, Taylor, Taylor, Taylor, Telleria, Tiberti, Trindade, Unciti-Broceta, Uzonna, Uzonna, Van Den Abbeele, Vassella, Welburn, Welburn, Wellde, Wenzler, Willert, Yaro   +160 more
core   +1 more source

A histone methyltransferase modulates antigenic variation in African trypanosomes. [PDF]

PLoS Biology, 2008
To evade the host immune system, several pathogens periodically change their cell-surface epitopes. In the African trypanosomes, antigenic variation is achieved by tightly regulating the expression of a multigene family encoding a large repertoire of ...
Luisa M Figueiredo, Christian J Janzen, George A M Cross   +2 more
doaj   +1 more source