Results 31 to 40 of about 126,752 (271)

The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host-parasite interaction [PDF]

, 2014
Babesia spp. are tick-borne, intraerythrocytic hemoparasites that use antigenic variation to resist host immunity, through sequential modification of the parasite-derived variant erythrocyte surface antigen (VESA) expressed on the infected red blood cell
Allred, David R., Berriman, Matt, Darby, Alistair, Echaide, Ignacio Eduardo, Farber, Marisa, Gahlot, Sunayna, Gamble, John, Gupta, Diness, Gupta, Yask, Hall, Neil, Jackson, Andrew P., Jackson, Louise, Lingelbach, Klaus, Malandrin, Laurence, Malas, Tareq B., Moussa, Ehab, Nair, Mridul, Otto, Thomas D., Pain, Arnab, Quail, Mike A., Ramaprasad, Abhinay, Reid, Adam J., Sanders, Mandy, Sharma, Jyotsna, Shiels, Brian, Tait, Andy, Tracey, Alan, Wastling, Jonathan M., Weir, William, Willadsen, Peter, Xia, Dong   +30 more
core   +6 more sources

Interference of infectious bursal disease virus on antibody production against Newcastle disease and infectious bronchitis virus

Brazilian Journal of Poultry Science, 2006
This work has the objective of verifying the interference of infectious bursal disease virus in the antibody production against Newcastle disease virus and infectious bronchitis virus.
WM Cardoso, JLC Aguiar Filho, JM Romão, RPR Salles, SR Câmara, AA Siqueira, WF Oliveira, MHNR Sobral, RSC Texeira   +8 more
doaj   +1 more source

COLONOSCOPY AND CARCINOEMBRYONIC ANTIGEN VARIATIONS [PDF]

Arquivos de Gastroenterologia, 2014
Context Colonoscopy is essential for synchronous and metachronous cancer detection. Carcinoembryonic antigen is a colorectal cancer tumor marker, important as a follow-up tool in patients with previous colorectal cancer. False-positive carcinoembryonic antigen elevation results in multiples exams and in patient anxiety.
SOUSA, Rita G, NUNES, Ana, MEIRA, Tânia, CARREIRA, Olga, PIRES, Ana M, FREITAS, João   +5 more
openaire   +4 more sources

Characterization and gene expression analysis of the cir multi-gene family of plasmodium chabaudi chabaudi (AS) [PDF]

, 2012
Background: The pir genes comprise the largest multi-gene family in Plasmodium, with members found in P. vivax, P. knowlesi and the rodent malaria species.
Berriman, Matthew, Brugat, Thibaut, Böhme, Ulrike, Cunningham, Deirdre, Jackson, Andrew, Langhorne, Jean, Lawton, Jennifer, Otto, Thomas Dan, Pain, Arnab, Preiser, Peter, Reid, Adam James, Yan, Yam Xue   +11 more
core   +3 more sources

Rapid turnover of Plasmodium falciparum var gene transcripts and genotypes during natural non-symptomatic infections Rápida mudança de transcritos var e de génotipos de Plasmodium falciparum em infecções assintomáticas naturalmente adquiridas

Revista do Instituto de Medicina Tropical de São Paulo, 2005
The var genes of Plasmodium falciparum code for the antigenically variant erythrocyte membrane proteins 1 (PfEMP1), a major factor for cytoadherence and immune escape of the parasite.
Gerhard Wunderlich, Fabiana P. Alves, Uta Gölnitz, Mauro S. Tada, Erney F.P. de Camargo, Luiz H. Pereira-da-Silva   +5 more
doaj   +1 more source

Influenza A virus hemagglutinin antibody escape promotes neuraminidase antigenic variation and drug resistance. [PDF]

PLoS ONE, 2011
Drugs inhibiting the influenza A virus (IAV) neuraminidase (NA) are the cornerstone of anti-IAV chemotherapy and prophylaxis in man. Drug-resistant mutations in NA arise frequently in human isolates, limiting the therapeutic application of NA inhibitors.
Scott E Hensley, Suman R Das, James S Gibbs, Adam L Bailey, Loren M Schmidt, Jack R Bennink, Jonathan W Yewdell   +6 more
doaj   +1 more source

The effects of symmetry on the dynamics of antigenic variation

, 2012
In the studies of dynamics of pathogens and their interactions with a host immune system, an important role is played by the structure of antigenic variants associated with a pathogen.
A Fässler, A Marcello, B Adams, B Fiedler, C Jones, C Newbold, C Stockdale, CA Pinto, CMR Turner, CO Buckee, CO Buckee, DG Aronson, DJ Smith, DL Martin, H Farkas, I Stewart, IM Rouzine, JD Barry, JD Murray, JHP Dawes, JL Mitchell, JL Muñoz-Jordán, JR Gog, JW Swift, KA Lythgoe, KB Blyuss, Konstantin B. Blyuss, KW Deitsch, LJ Abu-Raddad, LM Pecora, M Dellnitz, M Golubitsky, M Golubitsky, M Golubitsky, M Golubitsky, M Recker, M Recker, M Recker, M Recker, M Recker, MGM Gomes, MJ Gardner, O Bagasra, P Ashwin, P Ashwin, P Borst, P De Leenheer, P Hagblom, P Minaev, PL Buono, R Antia, S Gupta, S Gupta, S Gupta, S Kyes, S Lutenschlager, SA Frank, SA Frank, SH Strogatz, V Calvez, Y Jiang, Z Agur   +61 more
core   +1 more source

African Trypanosomes undermine humoral responses and vaccine development : link with inflammatory responses? [PDF]

, 2017
African trypanosomosis is a debilitating disease of great medical and socioeconomical importance. It is caused by strictly extracellular protozoan parasites capable of infecting all vertebrate classes including human, livestock, and game animals.
Achcar, Alampour-Rajabi, Alirol, Allman, Authie, Authié, Auty, Baker, Balber, Banks, Barry, Barry, Berthier, Beschin, Beschin, Blom-Potar, Bockstal, Bockstal, Boller, Bonnet, Borst, Bosschaerts, Boulange, Bouyer, Brun, Brun, Bucheton, Calandra, Capewell, Chamond, Claes, Cnops, Cnops, Cnops, Cnops, Coller, Dagenais, Darji, De Muylder, De Trez, Delafosse, Delespaux, Desquesnes, Devine, Disease, Drennan, Dubois, Duszenko, Engstler, Fenn, Ferrante, Field, Figarella, Franco, Frenkel, Gilbert, Giordani, Gomez-Rodriguez, Graham, Graham, Haanstra, Hall, Hasker, Hemphill, Holland, Holland, Holt, Jamonneau, Jarvinen, Jones, Keitany, Kennedy, Kennedy, Klasen, Kondo, Kroubi, Kuriakose, La Greca, La Greca, Lalmanach, Lanca, Lebien, Lejon, Lejon, Leng, MacGregor, MacGregor, MacLean, MacLean, Magez, Magez, Magez, Mansfield, McGettrick, Mekori, Millar, Mogk, Mony, Morrison, Morrison, Morrison, Mulindwa, Mårtensson, Naessens, Naula, Ng, Nutt, Obishakin, Odongo, Onyilagha, Ooi, Ooi, Osório, O’Gorman, Paulnock, Pays, Peacock, Priotto, Radwanska, Radwanska, Reth, Rico, Rodgers, Rotureau, Ruiz-Postigo, Salmon, Schwede, Schwede, Seed, Sharpe, Sileghem, Sileghem, Simarro, Simarro, Simarro, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Swallow, Takeya, Taylor, Taylor, Taylor, Telleria, Tiberti, Trindade, Unciti-Broceta, Uzonna, Uzonna, Van Den Abbeele, Vassella, Welburn, Welburn, Wellde, Wenzler, Willert, Yaro   +160 more
core   +1 more source

A histone methyltransferase modulates antigenic variation in African trypanosomes. [PDF]

PLoS Biology, 2008
To evade the host immune system, several pathogens periodically change their cell-surface epitopes. In the African trypanosomes, antigenic variation is achieved by tightly regulating the expression of a multigene family encoding a large repertoire of ...
Luisa M Figueiredo, Christian J Janzen, George A M Cross   +2 more
doaj   +1 more source

Recent advances in malaria genomics and epigenomics [PDF]

, 2016
Malaria continues to impose a significant disease burden on low- and middle-income countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid sequencing, reverse genetics, and post-genome analyses has generated step ...
Kirchner, Sebastian, Power, B. Joanne, Waters, Andrew P.   +2 more
core   +1 more source