Results 71 to 80 of about 126,752 (271)

Antigenic variation of Campylobacter flagella [PDF]

Journal of Bacteriology, 1987
Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of flagella dissociated from strains of Campylobacter coli and Campylobacter jejuni belonging to the heat-labile serogroup LIO 8 showed that some strains were capable of producing flagellin subunits of two different molecular weights (MrS), 59,500 and 61,500.
Harris, L., Logan, S., Guerry, P., Trust, T.   +3 more
openaire   +3 more sources

Tracking TCRß sequence clonotype expansions during antiviral therapy using high-throughput sequencing of the hypervariable region [PDF]

, 2016
To maintain a persistent infection viruses such as hepatitis C virus (HCV) employ a range of mechanisms that subvert protective T cell responses. The suppression of antigen-specific T cell responses by HCV hinders efforts to profile T cell responses ...
Arvind H Patel, Emma C Thomson, Gavin S Wilkie, John eMcLauchlan, Joseph eHughes, Mark W Robinson, Mark W Robinson, Peter R Mills, Rachael eSwann, Rachael eSwann, Stephen T Barclay   +10 more
core   +3 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Virulence and molecular adaptation of human urogenital mycoplasmas: a review

Biotechnology & Biotechnological Equipment, 2019
The pathogenesis of mycoplasmas requires their attachment to the epithelial mucosa membrane of the host cells, followed by colonisation and necrotic destruction of the submucosal tissue.
Orville Roachford, Karen Elizabeth Nelson, Bidyut Ranjan Mohapatra   +2 more
doaj   +1 more source

Beneath the surface: Amino acid variation underlying two decades of dengue virus antigenic dynamics in Bangkok, Thailand.

PLoS Pathogens, 2022
Neutralizing antibodies are important correlates of protection against dengue. Yet, determinants of variation in neutralization across strains within the four dengue virus serotypes (DENV1-4) is imperfectly understood.
Angkana T Huang, Henrik Salje, Ana Coello Escoto, Nayeem Chowdhury, Christian Chávez, Bernardo Garcia-Carreras, Wiriya Rutvisuttinunt, Irina Maljkovic Berry, Gregory D Gromowski, Lin Wang, Chonticha Klungthong, Butsaya Thaisomboonsuk, Ananda Nisalak, Luke M Trimmer-Smith, Isabel Rodriguez-Barraquer, Damon W Ellison, Anthony R Jones, Stefan Fernandez, Stephen J Thomas, Derek J Smith, Richard Jarman, Stephen S Whitehead, Derek A T Cummings, Leah C Katzelnick   +23 more
doaj   +1 more source

Antigenic Relationships among Human Pathogenic Orientia tsutsugamushi Isolates from Thailand [PDF]

, 2016
Scrub typhus is a common cause of undiagnosed febrile illness in certain tropical regions, but can be easily treated with antibiotics. The causative agent, Orientia tsutsugamushi, is antigenically variable which complicates diagnosis and efforts towards ...
Blacksell, S.D. (Stuart D.), Day, N.P.J. (Nicholas P. J.), James, S.L. (Sarah ), Nawtaisong, P. (Pruksa), Paris, D.H. (Daniel H.), Smith, D.J. (Derek James), Tanganuchitcharnchai, A. (Ampai)   +6 more
core   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Serological characteristics of some putative hybrid individuals from a Pinus sylvestris x Pinus mugo hybrid swarm population

Acta Societatis Botanicorum Poloniae, 2014
The antigenic properties of some putative hybrid individuals from a hybrid swarm population were studied. All the plants were to a major or lesser degree intermediate between three pure taxa, i.e. P. sylvestris, P. mugo and P. uliginosa.
Wiesław Prus-Gowacki, Jerzy Szweykowski
doaj   +1 more source

The impact of mutation and gene conversion on the local diversification of antigen genes in African trypanosomes [PDF]

, 2012
Patterns of genetic diversity in parasite antigen gene families hold important information about their potential to generate antigenic variation within and between hosts.
Awadalla, Berriman, C. A. Cobbold, D. T. Haydon, E. Gjini, Hutchinson, J. D. Barry, Jackson, Morrison, Parham, Parham, Sawyer, Westesson   +12 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source