Results 141 to 150 of about 46,788 (276)

Novel immunotherapies for immune-mediated haemolytic anaemia in dogs and people [PDF]

open access: yes, 2015
Aerts   +111 more
core   +1 more source

Marked efficacy of Rituximab in multifocal motor neuropathy associated with chronic lymphocytic leukemia [PDF]

open access: yes, 2016
The authors describe a patient who presented a multifocal motor neuropathy (MMN) associated with a high anti-ganglioside antibody (anti-GM1 and anti-GD1) titer at the clinical onset of a B-cell chronic lymphocytic leukemia (B-CLL). Immunomodulation (IVIg
Antonella Di, Pasquale   +6 more
core  

Spatial transcriptomics mapping of immune cell and TGFβ signalling pathway heterogeneity in testicular germ cell tumours

open access: yesAndrology, EarlyView.
Abstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Sarah C. Moody   +6 more
wiley   +1 more source

Thyroid Autoimmunity as a Window to Autoimmunity: An Explanation for Sex Differences in the Prevalence of Thyroid Autoimmunity [PDF]

open access: yes, 2015
Autoimmune thyroid diseases (AITDs), predominately Graves׳ disease and Hashimoto׳s thyroiditis, comprise the most common autoimmune diseases in humans.
Merrill, Stephen, Mu, Ying
core   +1 more source

A critical review of management of allogeneic transplant‐eligible adults with Ph+ acute lymphoblastic leukaemia

open access: yesBritish Journal of Haematology, EarlyView.
Proposed management of newly diagnosed Philadelphia chromosome‐positive (Ph+) acute lymphoblastic leukaemia (ALL) in transplant‐eligible patients. Suggested considerations when deciding the treatment pathway available to a newly diagnosed Ph+ ALL patient that would be deemed transplant eligible. Summary Acute lymphoblastic leukaemia (ALL) in 20%–30% of
Naranie Shanmuganathan, Andrew Grigg
wiley   +1 more source

Biologics in Systemic Lupus Erythematosus: Recent Evolutions and Benefits

open access: yesPharmaceutics
Introduction: Systemic lupus erythematosus (SLE) is a multifaceted autoimmune disorder characterized by significant autoantibodies, particularly targeting nuclear antigens. SLE pathogenesis involves genetic, environmental, and hormonal factors.
Nilima Rajpal Kundnani   +6 more
doaj   +1 more source

The anti‐CD47 antibody magrolimab with obinutuzumab and venetoclax in relapsed or refractory indolent B‐cell lymphomas

open access: yesBritish Journal of Haematology, EarlyView.
Follicular lymphoma (FL), marginal zone lymphoma (MZL), chronic lymphocytic leukaemia (CLL) and mantle cell lymphoma (MCL) are characterized by a continuous incidence of relapse and increasing resistance to therapy. Novel immunotherapy approaches are needed.
Rahul Lakhotia   +11 more
wiley   +1 more source

The expanding role of nuclear medicine in therapeutic strategies [PDF]

open access: yes, 2008
The concept of carrying a cytotoxic radionuclide directly to cancerous cells is an attractive alternative to conventional forms of radiation treatment.
Aquilina, Mark Anthony
core  

CD123‐targeting immunotherapeutic approaches in acute myeloid leukaemia

open access: yesBritish Journal of Haematology, EarlyView.
Summary Treatment of relapsed or refractory acute myeloid leukaemia (AML) has remained a significant challenge, with limited available targeted immunotherapies. CD123, or the interleukin‐3 (IL‐3) receptor, has long been known as a potential target expressed on AML blasts, and a range of different approaches to targeting CD123 have been trialled with ...
Alexandra Dreyzin   +2 more
wiley   +1 more source

A unique cellular and molecular microenvironment is present in tertiary lymphoid organs of patients with spontaneous prostate cancer regression [PDF]

open access: yes, 2017
de la Luz Garcia-Hernandez, Maria   +5 more
core   +2 more sources

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