Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman +2 more
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Prevalence of CD20 positive B-cells in peripheral blood of patients with lymphocytic lymphoma and correlation with the course of disease [PDF]
Emmerich, B. +3 more
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B Cell Differentiation Model for Identifying Predictors of Responses to Rituximab-Mediated B Cell Depletion in Rheumatic Diseases. [PDF]
Nakada T, Mager DE.
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This study presents an integrative pipeline linking immune cell traits to multiple sclerosis (MS) susceptibility. Genome‐wide association and Mendelian randomization analyses revealed causal roles of immune cells in MS risk. Colocalization and pleiotropy mapping identified candidate genes, further refined through functional annotation, network analysis,
Xuefei Wang, Yangwei Wang, Xiaojing Liu
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Rituximab in Connective Tissue Disease-Associated Interstitial Lung Disease: From Immunopathogenesis to Therapeutic Implications. [PDF]
Chatzis D +4 more
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ABSTRACT Background Immune checkpoint inhibitors (ICIs) have improved outcomes across several cancers, yet many patients do not respond, highlighting the need for robust predictive biomarkers. Tertiary lymphoid structures (TLS), ectopic lymphoid aggregates that support local antigen presentation and adaptive immune activation, have emerged as potential
Lidia B. Medhin +5 more
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Novel immunotherapeutic strategies for diffuse large B-cell lymphoma: a comprehensive review. [PDF]
Li Y +6 more
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ABSTRACT Introduction The immune microenvironment plays a crucial role in the progression of colorectal cancer (CRC), but its variation across primary tumors and metastatic sites remains incompletely understood. In this study, we compared the composition and prognostic significance of the immune microenvironment in lung metastases, paired primary ...
Danyil Kuznyecov +6 more
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Histological changes of conjunctiva-associated lymphoid tissue caused by pneumonia in Holstein young cows. [PDF]
Kosenda K +11 more
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Primary Diffuse Large B‐Cell Lymphoma Mimicking a Dental Abscess: A Case Report
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin lymphoma, yet its presentation in the maxillofacial region can pose diagnostic challenges, particularly in patients with confounding medical histories. We report the case of a 40‐year‐old Iranian male with a history of ulcerative colitis on mesalazine therapy, who ...
Haniyeh Najafi Aghdam +2 more
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