eJHaem, Volume 6, Issue 4, August 2025.ABSTRACT The incidence of central nervous system (CNS) involvement in mycosis fungoides (MF) is low. Here, we report a case of CNS involvement 3 years after MF diagnosis, comparing genetic alterations identified by amplicon‐based targeted sequencing between a primary skin sample and a brain tissue sample.
Yasumasa Nakata +6 more
wiley +1 more source
Beyond BCL2 (B cell lymphoma) and BTK (Bruton tyrosine kinase) inhibitors: novel agents and resistance mechanisms for chronic lymphocytic leukemia. [PDF]
Discov OncolHays P.
europepmc +1 more source
Journal of Medical Virology, Volume 97, Issue 8, August 2025.ABSTRACT Bovine meat and milk factors (BMMFs) are plasmid‐like DNA molecules isolated from cow's milk, meat, and human cancer tissues proposed to contribute to the development of specific types of cancer including colorectal cancer (CRC) and breast cancer based on chronic inflammation‐associated indirect carcinogenesis.
Sumen Siqin +17 more
wiley +1 more source
Resolving the structural basis of therapeutic antibody function in cancer immunotherapy with RESI. [PDF]
Nat CommunPachmayr I +9 more
europepmc +1 more source
Preclinical Vocal Fold and Airway Injury Models: A Scoping Review
Laryngoscope Investigative Otolaryngology, Volume 10, Issue 4, August 2025.Preclinical models are necessary to study novel therapeutics for laryngotracheal diseases. Currently, no consensus on species, injury mechanics, and study duration exists. This study reviews and organizes approaches to vocal fold (VF) and laryngotracheal injuries in preclinical models.
Rahul D. Patel +6 more
wiley +1 more source
Tandem CAR-T cell therapy: recent advances and current challenges. [PDF]
Front ImmunolGómez-Melero S +5 more
europepmc +1 more source
Type 1 diabetes presenting in adults: Trends, diagnostic challenges and unique features
Diabetes, Obesity and Metabolism, Volume 27, Issue S6, Page 57-68, August 2025.Abstract Type 1 diabetes (T1D) has been historically regarded as a childhood‐onset disease; however, recent epidemiological data indicate that adult‐onset T1D accounts for a substantial proportion of cases worldwide. There is evidence that adult‐onset T1D is associated with the classic T1D triad of elevated genetic risk, the presence of islet‐specific ...
Carmella Evans‐Molina, Richard A. Oram
wiley +1 more source
CD20-bearing extracellular vesicles are associated with prognostic biomarkers of patients with AIDS-NHL. [PDF]
Sci RepMartínez LE +9 more
europepmc +1 more source
Type 1 Diabetes: A Guide to Autoimmune Mechanisms for Clinicians
Diabetes, Obesity and Metabolism, Volume 27, Issue S6, Page 40-56, August 2025.Abstract Type 1 diabetes (T1D) results from the destruction of pancreatic beta cells by autoreactive T lymphocytes, leading to insulin deficiency and lifelong insulin dependence. It develops in genetically predisposed individuals, triggered by environmental or immunological factors.
François‐Xavier Mauvais +1 more
wiley +1 more source
JCMM Annual Review on Advances in Biotechnology for the Treatment of Haematological Malignancies: A Review of the Latest In-Patient Developments 2024-2025. [PDF]
J Cell Mol MedShahid AM +2 more
europepmc +1 more source