Results 51 to 60 of about 32,649 (166)

Diagnostic value of immunohistochemistry staining of Bcl-2, CD34, CD20 and CD3 for distinction between discoid lupus erythematosus and lichen planus in the skin

Indian Journal of Pathology and Microbiology, 2017
Background: Cluster of differentiation (CD) markers is a classification system for monoclonal antibodies against cell surface molecules on leukocytes and antigens from other cells. Aims: The aim of this study is to evaluate immunohistochemical markers in
Mazaher Ramezani, Bita-Sadat Hashemi, Sedigheh Khazaei, Mansour Rezaei, Ali Ebrahimi, Masoud Sadeghi   +5 more
doaj   +1 more source

Rituximab (Mabthera), a new approach for the treatment of rheumatoid arthritis. A systematic review [PDF]

Einstein (São Paulo), 2007
Rituximab is a chimeric monoclonal antibody capable of depleting Bcells expressing CD20. Clinical trials carried out in patients diagnosedwith active, established RA confirm that a single cycle of rituximabgiven as two infusions a week apart, together ...
Eduardo Finger, Morton Aaron Scheinberg
doaj  

Molecular assessment of intratumoral immune cell subsets and potential mechanisms of resistance to odronextamab, a CD20×CD3 bispecific antibody, in patients with relapsed/refractory B-cell non-Hodgkin lymphoma

Journal for ImmunoTherapy of Cancer
Background Patients with relapsed/refractory B-cell non-Hodgkin lymphoma (R/R B-NHL) have a significant need for effective treatment options. Odronextamab is an Fc-silenced, human, CD20×CD3 bispecific antibody that targets CD20-expressing cells via T ...
Dina M Flink, Se Jeong, Gavin Thurston, Rajat Bannerji, Vladimir Jankovic, Nathalie Fiaschi, Max S Topp, Jurriaan Brouwer-Visser, Raquel P Deering, Kamil J Cygan, Darius Scott, Lauren Boucher, Namita T Gupta, Suraj Gupta, Christina Adler, Johannes Duell, Ranjana H Advani, Aafia Chaudhry, Srikanth R Ambati   +18 more
doaj   +1 more source

P106 | Cd20 positive multiple myeloma: is it a different entity?

Haematologica
Introduction. Expression of CD20 antigen is generally negative in patients (pts) with multiple myeloma (MM). However, a small number of MM pts (15-20%) can show CD20 positivity on neoplastic plasma cells (PC).
Monica Poscente
doaj  

Caracterización inmunofenotípica de la leucemia linfoide crónica-B Immunophenotypical characterization of B-cell chronic lymphocytic leukemia

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2007
Se realizó la caracterización inmunofenotípica de 115 pacientes con leucemia linfoide crónica de fenotipo B, de células procedentes de médula ósea y sangre periférica mediante un ultramicrométodo inmunocitoquímico en el Instituto de Hematología e ...
Miriam Sánchez Segura, Vianed Marsán Suárez, Bertha Beatriz Socarrás Ferrer, Yanelkys Cos Padrón, René Rivero Jiménez, Mercedes Martínez Machado, Isabel María Torres Leyva, Lázaro O del Valle Pérez, Porfirio Hernández Ramírez, Consuelo Macías Abraham   +9 more
doaj  

Potassium/sodium cation carriers robustly up-regulate CD20 antigen by targeting MYC, and synergize with anti-CD20 immunotherapies to eliminate malignant B cells

Haematologica
Our investigation uncovers that nanomolar concentrations of salinomycin, monensin, nigericin, and narasin (a group of potassium/sodium cation carriers) robustly enhance surface expression of CD20 antigen in B-cell-derived tumor cells, including primary malignant cells of chronic lymphocytic leukemia and diffuse large B-cell lymphoma.
Toruń, Anna, Zdanowicz, Aleksandra, Nina Miązek-Zapała, Piotr Zapała, Pradhan, Bhaskar, Jędrzejczyk, Marta, Andrzej Ciechanowicz, Zofia Pilch, Marcin Skórzyński, Słabicki, Mikołaj, Rymkiewicz, Grzegorz, Barankiewicz, Joanna, Martines, Claudio, Laurenti, Luca, Marta Katarzyna Struga, Magdalena Winiarska, Jakub Adam Gołąb, Magdalena Kucia, Mariusz Ratajczak, Huczyński, Adam, Calado, Dinis, Efremov, Dimitar, Abdessamad Zerrouqi, Beata Pyrzyńska   +23 more
openaire   +3 more sources

Rituximab for the treatment of patients with chronic lymphocytic leukemia

Cancer Management and Research, 2010
M Gentile, E Vigna, C Mazzone, E Lucia, AG Recchia, L Morabito2, MG Bisconte, C Gentile, F Morabito1UOC di Ematologia, Azienda Ospedaliera di Cosenza, Italy; 2Servicio de Hematología y Hemoterapia, Hospital Universitario de Canarias, La Laguna,
M Gentile, E Vigna, C Mazzone, et al
doaj  

Preclinical B cell depletion and safety profile of a brain‐shuttled crystallizable fragment‐silenced CD20 antibody

Clinical and Translational Medicine
Background The blood–brain barrier (BBB) presents a major challenge for the development of monoclonal antibody (mAb)‐based therapies for brain disorders.
Vanessa L. Schumacher, Solen Pichereau, Juliana Bessa, Juergen Bachl, Sylvia Herter, Felix C. Weber, Johannes Auer, Anja Kipar, Michael Winter, Martina Stirn, Michael B. Otteneder, Kevin Brady, Anne Eichinger‐Chapelon, Adrian Roth, Nadine Stokar‐Regenscheit, Nicole Clemann, Shanon Seger, Claudia Senn, Juliane Hönig, Cordula Jany, Elisa Di Lenarda, Alain C. Tissot, Christian Klein, H.‐Christian vonBüdingen, Robert Mader, Mohammed Ullah, Niels Janssen, Eduard Urich   +27 more
doaj   +1 more source

Cure of a CD20-positive peripheral T-cell lymphoma-NOS with CHOPE regimen plus surgery a case report and literature review

Frontiers in Medicine
Peripheral T-cell lymphoma non-specific type (PTCL-NOS) is the most common subtype of mature T-cell tumors, which is clinically characterized by high invasiveness and poor prognosis.
Chenyu Chi, Shuo Wang, Man Xu, Yue Shi, Xuehong Ran   +4 more
doaj   +1 more source

CD20 Antigen Status [PDF]

, 2020
openaire   +1 more source