Results 41 to 50 of about 32,649 (166)
T Cells Expressing CD19/CD20 Bispecific Chimeric Antigen Receptors Prevent Antigen Escape by Malignant B Cells [PDF]
Cancer Immunology Research, 2016 Abstract The adoptive transfer of T cells expressing anti-CD19 chimeric antigen receptors (CARs) has shown remarkable curative potential against advanced B-cell malignancies, but multiple trials have also reported patient relapses due to the emergence of CD19-negative leukemic cells.
Zah, Eugenia +4 more
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CAR-T CELL THERAPY FOR FOLLICULAR LYMPHOMAS
Mediterranean Journal of Hematology and Infectious DiseasesFollicular lymphoma is the second most diagnosed lymphoma in Western Europe. Significant advancements have considerably improved the survival of FL patients.
Ugo Testa +4 more
doaj +1 more source
Infectious agents is a risk factor for myxomatous mitral valve degeneration: A case control study
BMC Infectious Diseases, 2017 Background The etiology of myxomatous mitral valve degeneration (MVD) is not fully understood and may depend on time or environmental factors for which the interaction of infectious agents has not been documented.
Marcos Gradim Tiveron +8 more
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Case Reports in Hematology, 2016 Diffuse large B-cell lymphoma (DLBCL) is a neoplasm of large B-lymphocytes with a diffuse growth pattern. The neoplastic cells express B-cell markers such as CD20 and PAX-5 and there may be coexpression of BCL-2, BCL-6, CD10, and MUM-1.
Elham Vali Betts, Hooman H. Rashidi
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Predicting the efficacy of anti-B-cell therapy in patients with multiple sclerosis [PDF]
Анналы клинической и экспериментальной неврологииIntroduction. Prognostic markers can be used to evaluate a response to anti-B-cell therapy in patients with multiple sclerosis (MS). Aim. The study aimed to evaluate the characteristics of peripheral blood (PB) lymphocytes and monocytes in patients ...
Yuliana A. Belova +2 more
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Sultan Qaboos University Medical Journal, 2012 Immunotherapy with T cells expressing chimeric antigen receptors (CAR) is being evaluated as a potential treatment for B-cell neoplasms. In recent clinical trials it has shown promising results.
Mohamed-Rachid Boulasse, Ahmed Galal
doaj
Analysis of transplant rejection in rabbits aponeurosis [PDF]
Einstein (São Paulo), 2012 Objective: To study the feasibility of heterologous aponeurosisto close the abdominal wall of rabbits emphasizing the rejectionprocess. Methods: This project was approved by the Animals CareCommittee of the Faculdade de Ciências Médicas da Santa Casa ...
Andre Ibrahim David +7 more
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ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS
Медицинская иммунология, 2014 . The aim of the present research was to study the expression of Fas-receptor and differentiation antigens CD3, CD4, CD8, CD16, CD20 on mononuclear cells of peripheral blood in the group of people with asimptomatic Zn-deficiency caused by geochemical ...
L. M. Karzakova
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CD20 positivity in classical Hodgkin′s lymphoma: Diagnostic challenge or targeting opportunity
Indian Journal of Pathology and Microbiology, 2009 Background: It is now well established that Hodgkin cells are clonal B cells with a CD30 and CD15 phenotype. However, on immunohistochemistry, in our experience and the experience of others, CD20 positivity in an otherwise typical classical Hodgkin ...
Barakzai Muhammad, Pervez Shahid
doaj
mSA2 affinity-enhanced biotin-binding CAR T cells for universal tumor targeting
OncoImmunology, 2018 Chimeric antigen receptor T cells (CAR-Ts) are promising cancer therapeutics. However, since cancer cells can lose the CAR-targeted antigen and avoid destruction, targeting multiple antigens with multiple CARs has been proposed. We illustrate here a less
Jason J. Lohmueller +3 more
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