Results 21 to 30 of about 231,458 (256)

Monoclonal antibody-based therapies for Waldenström's macroglobulinemia

Leukemia Research Reports, 2022
Monoclonal antibodies have established an important role in the treatment armamentarium of hematological malignancies, including Waldenström's macroglobulinemia.
Despina Fotiou, Foteini Theodorakakou, Efstathios Kastritis   +2 more
doaj   +1 more source

Mesenchymal stem cells promote leukaemic cells aberrant phenotype from B-cell acute lymphoblastic leukaemia

Hematology/Oncology and Stem Cell Therapy, 2013
BACKGROUND AND OBJECTIVES: The role of bone marrow-mesenchymal stem cells (BM-MSC) in leukae-mic cell control is controversial. The purpose of this work was to evaluate BM-MSC role regarding the viability, proliferation and immunophenotype of normal B ...
Viviana M Rodríguez-Pardo, José A Aristizabal, Diana Jaimes, Sandra M Quijano, Iliana de los Reyes, María Victoria Herrera, Julio Solano, Jean Paul Vernot   +7 more
doaj   +1 more source

Immunotherapy in indolent Non-Hodgkin's Lymphoma

Leukemia Research Reports, 2022
Treatment of non-Hodgkin lymphoma (NHL) in general has improved over the years with the emergence of the monoclonal antibodies (MAB) therapy. NHL is divided into B cell NHL and T cell NHL. Treatment of NHL was based on the subtype of NHL and its staging.
Ghid Amhaz, Ali Bazarbachi, Jean El-Cheikh   +2 more
doaj   +1 more source

FMC7 ist Teil des CD20-Antigenkomplexes [PDF]

, 2004
Das FMC7-Antigen, eine unbekannte B-Zell-Membranstruktur, dient als eines der immunphänotypischen Grundkriterien zur Diagnose der typischen B-CLL.
Jordanova, Maya
core   +1 more source

High-Grade Epstein-Barr Virus-Negative Biphenotypic Lymphoma with Expression of B- and T-Cell Markers and Leukemia Presentation: Case Report and Literature Review

Case Reports in Oncology, 2020
Lymphomas are presently categorized according to their origin from B or T lymphocytes. The co-expression of CD3 in B-cell lymphomas or CD20 in T-cell lymphomas has been rarely reported.
Samah Kohla, Feryal A. Ibrahim, Deena Mudawi, Susanna Akiki, Dina Soliman, Ahmad Al-Sabbagh, Reda R.H. Youssef, Mohamed A. Yassin   +7 more
doaj   +1 more source

Analysis of Cellular Component Indicators of Immune Status of Rhesus Macaques

Проблемы особо опасных инфекций, 2021
Objective. Selection of indicators of lymphocyte populations in rhesus macaques determined by flow cytometry to evaluate variations of cellular constituent of their immune status.Materials and methods.
G. V. Borisevich, S. L. Kirillova, O. N. Sidorova, V. N. Lebedev, A. A. Petrov, A. V. Ovchinnikov, I. V. Shatokhina, T. E. Sizikova, V. E. Sazonov, E. S. Mukhacheva, S. V. Borisevich   +10 more
doaj   +1 more source

DataSheet_1_Potent immunomodulatory and antitumor effect of anti-CD20-IL2no-alpha tri-functional immunocytokine for cancer therapy.pdf

, 2022
IntroductionThe anti-CD20 antibody rituximab (RTX) has substantially improved outcomes of patients with B-cell lymphomas, although more efficient therapies are needed for refractory or relapsing lymphomas.
Claudia Plasencia (14238803), Kalet León (2795161), Miguel Ángel González (14238785), Addys González (14238794), Beatriz María Cruz (14238779), Katya Sosa (14238797), Kathleen Castro (14238800), Nuris Ledón (4266283), Calixto Hernández (14238809), Tania Gómez (14238788), Tays Hernández (14238812), Ana Victoria Casadesús (14238776), Wilden Díaz (14238782), Briandy Fernández (14238791), Armando López (541227), Jean-Luc Teillaud (154584), Yaima Ramírez (14238806)   +16 more
core   +1 more source

The Role of Monoclonal Antibodies in the Management of Leukemia

Pharmaceuticals, 2010
This article will review the monoclonal antibodies more commonly used in leukemias. In the last three decades, scientists have made considerable progress understanding the structure and the functions of various surface antigens, such as CD20, CD33.
Mohamad Cherry, Aref Al-Kali, Ali Al-Ameri, Alessandra Ferrajoli   +3 more
doaj   +1 more source

Construction of tandem diabody (IL-6/CD20)-secreting human umbilical cord mesenchymal stem cells and its experimental treatment on diffuse large B cell lymphoma

Stem Cell Research & Therapy, 2022
Background More than 40% patients with diffuse large B cell lymphoma (DLBCL) experienced relapse or refractory (R/R) lymphoma after the standard first R-CHOP therapy. IL-6 was reportedly associated with chemotherapy resistance of rituximab.
Jiayi Zhang, Minglu Zhong, Weijie Zhong, Yanfei Lan, Zhaohu Yuan, Yuyou Duan, Yaming Wei   +6 more
doaj   +1 more source

CD20 deficiency in humans results in impaired T cell-independent antibody responses. [PDF]

, 2010
CD20 was the first B cell differentiation antigen identified, and CD20-specific mAbs are commonly used for the treatment of B cell malignancies and autoantibody-mediated autoimmune diseases.
Bende, R.J., Eldering, E., van Noesel, C.J.M., Ingrid A.M. Derks, Beaumont, T., Thomas F. Tedder, Paul A. Baars, Tim Beaumont, Beaumont, Tim, René A.W. van Lier, van Noesel, Carel JM, Grummels, Annette, Kuijpers, T.W., Eldering, Eric, Baars, Paul A, Tedder, Thomas F, Koert M. Dolman, van Lier, R.A.W., Dolman, K.M., Baars, P.A., Richard J. Bende, Taco W. Kuijpers, Annette Grummels, Bende, Richard J, van Lier, René AW, Derks, Ingrid AM, Tedder, T.F., Eric Eldering, Grummels, A., Kuijpers, Taco W, Dolman, Koert M, Derks, I.A.M., Carel J.M. van Noesel   +32 more
core   +1 more source