Results 11 to 20 of about 231,458 (256)

Immuno-biosensor for Detection of CD20-Positive Cells Using Surface Plasmon Resonance [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2017
Purpose: Surface plasmon resonance (SPR) sensing confers a real-time assessment of molecular interactions between biomolecules and their ligands. This approach is highly sensitive and reproducible and could be employed to confirm the successful binding ...
Dariush Shanehbandi   +6 more
doaj   +3 more sources

Humoral Response to SARS-CoV-2 Antigen in Patients Treated with Monoclonal Anti-CD20 Antibodies: It Is Not All about B Cell Recovery

open access: yesNeurology International, 2022
Anti-CD20 therapies decrease the humoral response to SARS-CoV-2 immunization. We aimed to determine the extent of the humoral response to SARS-CoV-2 antigens in correlation with peripheral B-cell dynamics among patients with central nervous system ...
Julia Feige   +11 more
doaj   +2 more sources

Monoclonal Antibodies: from Development to Clinical Application

open access: yesКлиническая онкогематология, 2016
The development of monoclonal antibodies (MABs) resulted in revolutionary achievements in diagnosing and treating of oncohematological disorders. The review dwells on the history of the development and improved technologies for production of monoclonal ...
Yurii Ivanovich Budchanov
doaj   +2 more sources

Development of a compact bidirectional promoter-driven dual chimeric antigen receptor (CAR) construct targeting CD19 and CD20 in the Sleeping Beauty (SB) transposon system

open access: yesJournal for ImmunoTherapy of Cancer
Background A bidirectional promoter-driven chimeric antigen receptor (CAR) cassette provides the simultaneous expression of two CARs, which significantly enhances dual antigen-targeted CAR T-cell therapy.Methods We developed a second-generation CAR ...
Supannikar Tawinwung   +6 more
doaj   +2 more sources

Rituximab Plus Chemotherapy Provides No Clinical Benefit in a Peripheral T-Cell Lymphoma not Otherwise Specified with Aberrant Expression of CD20 and CD79a: A Case Report and Review of the Literature [PDF]

open access: yesDiagnostics, 2020
Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is the most common entity of mature T-cell neoplasms. PTCL-NOS generally has an aggressive behavior and is often refractory to standard therapy.
Alessandro Mangogna   +5 more
doaj   +2 more sources

Treatment strategies for rituximab-resistant primary membranous nephropathy: from resistance mechanisms to emerging therapies [PDF]

open access: yesFrontiers in Immunology
With the expanding identification of target antigens in primary membranous nephropathy (PMN), treatment is shifting from empirical immunosuppression toward mechanism-based precision immunotherapy.
Jingjie Gao   +9 more
doaj   +2 more sources

Selection of an Anti-CD20, Single-Chain Antibody by Phage ELISA on Fixed Cells

open access: yesBioTechniques, 1999
Cloning the correct genes that code for antibody-variable domains from hybridomas is often complicated by the presence of several immunoglobulin transcripts, some of them arising from a myeloma cell line.
Stefanie Schmidt   +3 more
doaj   +2 more sources

CD20 positivity in classical Hodgkin′s lymphoma: Diagnostic challenge or targeting opportunity

open access: yesIndian Journal of Pathology and Microbiology, 2009
Background: It is now well established that Hodgkin cells are clonal B cells with a CD30 and CD15 phenotype. However, on immunohistochemistry, in our experience and the experience of others, CD20 positivity in an otherwise typical classical Hodgkin ...
Barakzai Muhammad, Pervez Shahid
doaj   +1 more source

Novel NKG2D-directed bispecific antibodies enhance antibody-mediated killing of malignant B cells by NK cells and T cells

open access: yesFrontiers in Immunology, 2023
The activating receptor natural killer group 2, member D (NKG2D) represents an attractive target for immunotherapy as it exerts a crucial role in cancer immunosurveillance by regulating the activity of cytotoxic lymphocytes.
Sebastian Lutz   +19 more
doaj   +1 more source

Application of anti-CD20 monoclonal antibodies in the treatment of lymphoproliferative diseases [PDF]

open access: yesArchive of Oncology, 2009
Out of numerous studied monoclonal antibodies, only a few reached the stage of clinical application. The CD20 molecule, non-glycolysed phospholipoprotein (usually termed B1), belonging to the tetraspan (TM4SF) family, 35-37 kD, is characteristic for all ...
Pejčić Ivica, Vrbić Svetislav
doaj   +1 more source

Home - About - Disclaimer - Privacy