Results 11 to 20 of about 32,649 (166)
Monoclonal Antibodies: from Development to Clinical Application
Клиническая онкогематология, 2016 The development of monoclonal antibodies (MABs) resulted in revolutionary achievements in diagnosing and treating of oncohematological disorders. The review dwells on the history of the development and improved technologies for production of monoclonal ...
Yurii Ivanovich Budchanov
doaj +1 more source
Immunotherapy in indolent Non-Hodgkin's Lymphoma
Leukemia Research Reports, 2022 Treatment of non-Hodgkin lymphoma (NHL) in general has improved over the years with the emergence of the monoclonal antibodies (MAB) therapy. NHL is divided into B cell NHL and T cell NHL. Treatment of NHL was based on the subtype of NHL and its staging.
Ghid Amhaz +2 more
doaj +1 more source
Iranian biomedical journal, 1996 Iranian Biomedical Journal (IBJ); ISSN 1028 ...
Mahdi, Habibi Anbouhi +9 more
openaire +2 more sources
Analysis of Cellular Component Indicators of Immune Status of Rhesus Macaques
Проблемы особо опасных инфекций, 2021 Objective. Selection of indicators of lymphocyte populations in rhesus macaques determined by flow cytometry to evaluate variations of cellular constituent of their immune status.Materials and methods.
G. V. Borisevich +10 more
doaj +1 more source
Case Reports in Oncology, 2020 Lymphomas are presently categorized according to their origin from B or T lymphocytes. The co-expression of CD3 in B-cell lymphomas or CD20 in T-cell lymphomas has been rarely reported.
Samah Kohla +7 more
doaj +1 more source
Stem Cell Research & Therapy, 2022 Background More than 40% patients with diffuse large B cell lymphoma (DLBCL) experienced relapse or refractory (R/R) lymphoma after the standard first R-CHOP therapy. IL-6 was reportedly associated with chemotherapy resistance of rituximab.
Jiayi Zhang +6 more
doaj +1 more source
The Role of Monoclonal Antibodies in the Management of Leukemia
Pharmaceuticals, 2010 This article will review the monoclonal antibodies more commonly used in leukemias. In the last three decades, scientists have made considerable progress understanding the structure and the functions of various surface antigens, such as CD20, CD33.
Mohamad Cherry +3 more
doaj +1 more source
Immunophenotyping of Waldenströms macroglobulinemia cell lines reveals distinct patterns of surface antigen expression: potential biological and therapeutic implications. [PDF]
PLoS ONE, 2015 Waldenströms macroglobulinemia (WM) is a subtype of Non-Hodgkin's lymphoma in which the tumor cell population is markedly heterogeneous, consisting of immunoglobulin-M secreting B-lymphocytes, plasmacytoid lymphocytes and plasma cells.
Aneel Paulus +7 more
doaj +1 more source
Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection [PDF]
Blood, 2010 Abstract Rituximab, a monoclonal antibody that targets CD20 on B cells, is now central to the treatment of a variety of malignant and autoimmune disorders. Despite this success, a substantial proportion of B-cell lymphomas are unresponsive or develop resistance, hence more potent anti-CD20 monoclonal antibodies (mAbs) are continuously
Beers, Stephen A. +15 more
openaire +4 more sources
BMC Cancer, 2009 Background Antibody-dependent cellular cytotoxicity (ADCC) has recently been identified as one of the critical mechanisms underlying the clinical efficacy of therapeutic antibodies, especially anticancer antibodies.
Okazaki Akira +7 more
doaj +1 more source