Results 111 to 120 of about 101,429 (314)

Extracellular vesicles from seminal plasma interact with T cells in vitro and drive their differentiation into regulatory T‐cells

Journal of Extracellular Vesicles
Seminal plasma induces immune tolerance towards paternal allogenic antigens within the female reproductive tract and during foetal development. Recent evidence suggests a role for extracellular vesicles in seminal plasma (spEVs).
Xiaogang Zhang, Patrick F. Greve, Thi Tran Ngoc Minh, Richard Wubbolts, Ayşe Y. Demir, Esther A. Zaal, Celia R. Berkers, Marianne Boes, Willem Stoorvogel   +8 more
doaj   +1 more source

Assessing the response of T cells to "Mycobacterium tuberculosis" lipids [PDF]

, 2008
Most vaccines used nowadays are created using inactivated or attenuated compounds from micro-organisms. Advances in basic immunology and molecular biology opened the gate for consequent improvement of vaccination strategies.
Collmann, Anthony
core   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Differential dynamics of the peripheral and intrahepatic cytotoxic T lymphocyte response to hepatitis B surface antigen

Virology, 2005
The distribution and dynamics of the cytotoxic T lymphocyte (CTL) response to hepatitis B surface antigen (HBsAg) were studied in mice after intramuscular DNA immunization and after hepatic infection by a recombinant adenovirus that expresses the hepatitis B virus genome (Ad-HBV).
Isogawa, Masanori, Kakimi, Kazuhiro, Kamamoto, Hiroyuki, Protzer, Ulrike, Chisari, Francis V.   +4 more
openaire   +2 more sources

Regulated progression of B lymphocyte differentiation from cultured fetal liver. [PDF]

, 1987
Lymphoid fetal liver cultures (LFLC) are long-term, nontransformed cultures of early B lymphoid lineage cells which appear developmentally blocked at the pre-B stage in vitro.
O N Witte, Witte, ON, K A Denis, Denis, KA, K Dorshkind, Dorshkind, K   +5 more
core   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

CHARACTERISTICS OF LYMPHOCYTE SUBPOPULATION COMPOSITION IN CANCER PATIENTS UNDERGOING COMBINED MODALITY TREATMENT INCLUDING ADAPTIVE IMMUNOTHERAPY

Сибирский онкологический журнал, 2016
Currently, cellular immunity can be estimated using the cluster of differentiation antigens or CD-markers. The panel of CD-markers including 6-8 parameters is usually used for assessment of cellular immunity.
E. V. Abakushina, Yu. V. Marizina, G. S. Neprina, D. V. Kudryavtsev, I. A. Pasova, N. V. Selivanova   +5 more
doaj  

The development and function of dendritic cell populations and their regulation by miRNAs

Protein & Cell, 2017
Dendritic cells (DCs) are important immune cells linking innate and adaptive immune responses. DCs encounter various self and non-self antigens present in the environment and induce different types of antigen specific adaptive immune responses.
Haibo Zhou, Li Wu
doaj   +1 more source

Theileria annulata and T. parva infect and transform different bovine mononuclear cells

, 1989
Bovine peripheral blood mononuclear cells (PBMC) were labelled with monoclonal antibodies recognizing bovine MHC class II, sIgM, monocyte, T-helper and T-cytotoxic cell phenotypes.
Brown, C G, Innes, E A, Spooner, R L, Glass, E J   +3 more
core  

Alpha (v) integrins license regulatory T cells to apoptotic cells and self-associated antigens

, 2010
Defects in apoptotic cell clearance are thought to contribute to autoimmunity by failure to induce tolerance, coupled with accumulation of immunogenic material.
Paidassi, Helena, Lacy-Hulbert, Adam, Helena Païdassi, Adam Lacy-Hulbert, Mridu Acharya, Acharya, Mridu   +5 more
core   +1 more source