Results 1 to 10 of about 18,221 (161)

Discovery of Antigens and Cellular Mechanisms in the Protozoan Parasite Sarcocystis aucheniae Using Immunoproteomics

Parasitologia, 2023
Sarcocystis aucheniae is a coccidian parasite that produces macroscopic sarcocysts in South American camelid (SAC) muscles and causes a disease known as SAC sarcocystosis.
Sarah Nathaly Wieser, Cecilia Decker-Franco, Paloma de Alba, Sandra Romero, Alejandro Ferrari, Leonhard Schnittger, Mónica Florin-Christensen   +6 more
doaj   +4 more sources

Computational vaccine development against protozoa [PDF]

Computational and Structural Biotechnology Journal
Protozoan parasites remain a major global health and economic burden, particularly in low- and middle-income countries. Conventional strategies such as chemotherapy and vector control face growing limitations due to resistance, toxicity, and ...
Omar Hashim, Isabelle Dimier-Poisson
doaj   +2 more sources

Strongyloides Antigens Alter Cytokines Responses in Toxoplasma gondii-Infected BeWo Trophoblast Cells. [PDF]

Cell Biol Int
ABSTRACT The importance of co‐infections is not yet completely understood, and the impact and direction of their effects vary considerably. This study aimed to evaluate the role of total saline extract (TS) and excretory/secretory (ES) products of Strongyloides venezuelensis filarioid larvae on a maternal‐interface cell model during Toxoplasma gondii ...
Alves FT, Jesus BCG, Diniz MES, Luz LC, Franco PS, Ribeiro VDS, de Carvalho EFG, Barbosa BF, Gonzaga HT.   +8 more
europepmc   +2 more sources

Different kinetics of humoral response against individual antigens in the ovine model of Toxoplasma gondii infection and its pathological association [PDF]

Frontiers in Immunology
BackgroundToxoplasma gondii is a globally distributed protozoan parasite with major implications for human and animal health. In sheep, infection can cause reproductive failure and represents an important source of zoonotic transmission through ...
Paula Formigo, Ignacio Gual, Ignacio Gual, Germán J. Cantón, Luisa F. Mendoza Morales, Luisa F. Mendoza Morales, Emiliano Sosa, Agustina Soto Cabrera, Valeria Scioli, Claudia Morsella, Valeria A. Sander, Dadin P. Moore, Dadin P. Moore, Sergio O. Angel, Lucía M. Campero, Marina Clemente   +15 more
doaj   +2 more sources

Plant Expression of Hydrophobin Fused K39 Antigen for Visceral Leishmaniasis Immunodiagnosis

Frontiers in Plant Science, 2021
Visceral leishmaniasis is a Neglected Tropical Disease of high mortality caused by the protozoan Leishmania infantum. Its transmission cycle is complex, and it has in the domestic dog its main reservoir.
Bruno B. Silva, Bruno B. Silva, Eduarda N. F. N. Santos, Eduarda N. F. N. Santos, Lucelina S. Araújo, Arnaldo S. Bezerra, Arnaldo S. Bezerra, Lívia É. C. Marques, Eridan O. P. Tramontina Florean, Maurício F. van Tilburg, Maurício F. van Tilburg, Maria Izabel F. Guedes, Maria Izabel F. Guedes   +12 more
doaj   +1 more source

Antibodies to variable surface antigens induce antigenic variation in the intestinal parasite Giardia lamblia

Nature Communications, 2023
The genomes of most protozoa encode families of variant surface antigens. In some parasitic microorganisms, it has been demonstrated that mutually exclusive changes in the expression of these antigens allow parasites to evade the host’s immune response ...
Albano H. Tenaglia, Lucas A. Luján, Diego N. Ríos, Cecilia R. Molina, Victor Midlej, Paula A. Iribarren, María A. Berazategui, Alessandro Torri, Alicia Saura, Damián O. Peralta, Macarena Rodríguez-Walker, Elmer A. Fernández, Juan P. Petiti, Marianela C. Serradell, Pablo R. Gargantini, Tim Sparwasser, Vanina E. Alvarez, Wanderley de Souza, Hugo D. Luján   +18 more
doaj   +1 more source

Conserved Candidate Antigens and Nanoparticles to Develop Vaccine against Giardia intestinalis

Vaccines, 2022
Giardia intestinalis (Giardia lambia, Giardia duodenalis) infections in humans may be asymptomatic or symptomatic and associated with diarrhea (without blood), abdominal cramps, bloating, flatulence, and weight loss.
Suthinee Sangkanu, Alok K. Paul, Julalak Chuprom, Watcharapong Mitsuwan, Rachasak Boonhok, Maria de Lourdes Pereira, Sonia Marlene Rodrigues Oliveira, Polrat Wilairatana, Mohammed Rahmatullah, Christophe Wiart, Muhammad Nawaz, Chea Sin, Sunil Kayesth, Veeranoot Nissapatorn   +13 more
doaj   +1 more source

Development of Nano-ELISA Method for Serological Diagnosis of Toxoplasmosis in Mice [PDF]

Archives of Razi Institute, 2021
Toxoplasmosis is a widespread parasitic disease caused by a protozoan parasite Toxoplasma gondii. Currently, nanotechnology has been used for the diagnosis of many infectious diseases. It could be due to the fact that nanoparticles play an important role
A. Khodadadi, R. Madani, N. Hoghooghi Rad, N. Atyabi   +3 more
doaj   +1 more source

Determination the Time of Toxoplasmosis among Pregnant Women by using IgG Avidity to Various Toxoplasma Gondii Antigens [PDF]

Kirkuk Journal of Science, 2019
Toxoplasmosis is caused by Toxoplasma gondii, which is an intracellular protozoan parasite. Its main host is the cat. It is one of the most common human parasites. The main objective of this study is to determine the time of T.
Sanarya Tawfiq, Zainab Rezaig, Mohemid Al- Jebouri   +2 more
doaj   +1 more source

Parasite Carbohydrate Vaccines

Frontiers in Cellular and Infection Microbiology, 2017
Vaccination is an efficient means of combating infectious disease burden globally. However, routine vaccines for the world's major human parasitic diseases do not yet exist. Vaccines based on carbohydrate antigens are a viable option for parasite vaccine
Jonnel A. Jaurigue, Jonnel A. Jaurigue, Peter H. Seeberger, Peter H. Seeberger   +3 more
doaj   +1 more source