Recombinant subunit vaccines against Neospora caninum [PDF]
The intracellular protozoan parasite Neospora caninum is an important cause of bovine abortion and congenital infection in many countries. Currently there is no effective control method available, and development of a vaccine has been suggested as a ...
Pinitkiatisakul, Sunan
core
Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella [PDF]
Eimeria tenella, the causative agent of caecal coccidiosis, is a pathogenic gut dwelling protozoan which can cause severe morbidity and mortality in farmed chickens.
Banerjee, P S+6 more
core +1 more source
Positive serology titres for Neospora caninum in the absence of appropriate clinical signs is not diagnostic for protozoal disease. Acute deterioration while immunosuppressed should raise concerns over reactivation of encysted protozoa, particularly in dogs with a history of raw feeding. Successful management of N. caninum appears possible but requires
Perrine Henry+3 more
wiley +1 more source
Characterization of novel microneme adhesive repeats (MAR) in Eimeria tenella [PDF]
In this study, we evaluated the binding capacity of Type I MAR domains from novel E. tenella MCPs. Variants of the previously described HxT motif were analysed showing that HxT and VxT variants bind, whereas HxS and YxE variants did not. One of these MCP
Marugan-Hernandez, V+5 more
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ILC2 Diversity, Location, and Function in Pulmonary Disease
ABSTRACT Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2 inflammation are important contributors to the weep‐and‐sweep responses observed in the ...
Mukesh Verma+2 more
wiley +1 more source
A case of visceral leishmaniasis mimicking connective tissue disease
Rheumatology &Autoimmunity, EarlyView.
Yucui Li+4 more
wiley +1 more source
Cost‐Effective Nanosensor Solutions for Ultra‐Sensitive Detection of Metronidazole
ABSTRACT Metronidazole (MNZ) is a widely used imidazole antibiotic effective against bacterial and protozoal infections, including giardiasis, trichomoniasis, bacterial vaginosis, and antibiotic‐associated colitis. However, prolonged and excessive use of MNZ can lead to serious side effects, such as peripheral neuropathies, toxicity, and optic ...
Ahmad Mobed+6 more
wiley +1 more source
Monoclonal Antibodies against the Drosophila Nervous System [PDF]
A panel of 148 monoclonal antibodies directed against Drosophila neural antigens has been prepared by using mice immunized with homogenates of Drosophila tissue. Antibodies were screened immunohistochemically on cryostat sections of fly heads.
Benzer, Seymour+4 more
core +1 more source
Lactylation: From Homeostasis to Pathological Implications and Therapeutic Strategies
Lactylation, a novel post‐translational modification derived from lactate metabolism, plays a critical role in cellular homeostasis and disease pathogenesis. Under physiological conditions, lactylation regulates gene expression, immune responses, and metabolic adaptation. However, dysregulated lactylation is implicated in various pathological processes,
Xi Chen+6 more
wiley +1 more source
Selection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro [PDF]
Parasite infections are largely dependent on interactions between pathogen and different host cell populations to guarantee a successful infectious process.
Alves, Maria Julia Manso+2 more
core +2 more sources