Results 231 to 240 of about 45,582 (279)

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

The Prebiotic and Techno‐Functional Potential of Microbial Exopolysaccharides for Human Health and Food Systems

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 2, March 2026.
ABSTRACT Microbial exopolysaccharides (EPS) represent a diverse class of biopolymers holding considerable promise as functional food ingredients. This review analyzes the dual function of microbial EPS as a candidate for prebiotic agents and techno‐functional additives.
Md. Abdur Razzak, Hye Kim, Md. Ariful Haque, Min Ji Jang, Sehyeon Song, Anishka Talari, Lakshmi Devi Chittepu, Seockmo Ku   +7 more
wiley   +1 more source

Sequential microwave ablation combined with radioactive iodine-125 seed implantation successfully cured multiple metastases of gallbladder cancer: A case report. [PDF]

Oncol Lett
Li W, Chen Y, Zhao S, An M, Zhao H, Cai Y, Bao J, Qian J, Chen B.   +8 more
europepmc   +1 more source

Circulating Myokine Responses to Acute Endurance Exercise and Their Role in Immunoregulation: A Systematic Review and Meta‐Analysis

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
This systematic review and meta‐analysis, which examined the effects of acute endurance training on immunoregulatory myokines, showed significant small‐moderate to very large positive effect sizes for IL‐6, IL‐10, IL‐1ra, IL‐8, IL‐15, and TNF‐α. These effects were significantly moderated by risk of bias, sex, age, V̇O2peak, experience, type of exercise,
Miriam Ringleb, Fabian Fabritius, Jakob Godde, Christian Puta, Wilhelm Bloch, Florian Javelle   +5 more
wiley   +1 more source

CAR-T therapy: Advances in respiratory diseases. [PDF]

Chin Med J Pulm Crit Care Med
Han H, Hu Y.
europepmc   +1 more source

Cardiomyocyte‐Derived USP20 Attenuates Diabetic Cardiomyopathy by Facilitating the Degradation of STING and Mitigating STING‐Mediated Inflammation

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
USP20 directly binds to STING and promotes the degradation of STING through the autophagy pathway by deubiquitinating p62 via its active site C154, thereby alleviating myocardial inflammation and improving ventricular remodeling and heart failure induced by diabetes. ABSTRACT Although extensive clinical and basic research has been conducted on diabetic
Yixin Zhou, Miaomiao Ying, Baozhen Qi, Yunxuan Chen, Weihong Lin, Chunwu Zhang, Jiahui Lin, Yucong Zhang, Zexin Yang, Ziyi Huang, Jun Wu, Xueli Cai, Weijian Huang, Zhouqing Huang, Zhenfeng Cheng, Shanshan Dai   +15 more
wiley   +1 more source

MYCN-Driven Metabolic Networks Are a Critical Dependency of High-Risk Neuroblastomas. [PDF]

Cancers (Basel)
Pitts MG, Bryant LT, Buoncristiani MD, Rellinger EJ.   +3 more
europepmc   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, Volume 36, Issue 11, 5 February 2026.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Probing the Broad-Spectrum Virus-Neutralizing Epitopes Using the High-Density Oligomannose-Conjugates and Carbohydrate Microarrays. [PDF]

Bioconjug Chem
Toonstra C, Wu L, Wang LX, Wang D.
europepmc   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, Volume 15, Issue 6, 9 February 2026.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source