Results 261 to 270 of about 45,582 (279)
Some of the next articles are maybe not open access.
[Tumor-associated carbohydrate antigens related to blood group carbohydrates].
Gan to kagaku ryoho. Cancer & chemotherapy, 1986Biochemical studies have revealed the alteration of carbohydrate structures of cell membrane glycolipids, glycoproteins and cell secretory products associated with neoplastic transformation. Immunohistochemical examination of the blood group carbohydrate antigens in various cancer tissues have revealed the following results.
openaire +1 more source
Possible roles of tumor-associated carbohydrate antigens.
Cancer research, 1996Recent progress in the studies on the roles of carbohydrates has brought about critical discoveries, which allow us to have working hypotheses for understanding the roles of tumor-associated carbohydrate antigens. In this report, I focus my description on three different aspects of this progress.
openaire +1 more source
Chapter 4 Tumor-associated carbohydrate antigens and modified blood group antigens
1996Publisher Summary This chapter discusses the present knowledge of tumor-associated carbohydrate antigens (TACA's). It also discusses the pathobiological and functional significance of TACA's. A large number of monoclonal antibody (mAbs) showed distinctive reactivity with tumor cells but not with normal cells were found to be directed to carbohydrate ...
openaire +1 more source
Gan to kagaku ryoho. Cancer & chemotherapy, 2021
The Tn antigen is the most prevalent tumor-associated carbohydrate antigen. It interacts with macrophage galactose-specific lectin(MGL)on dendric cells and macrophages, driving immune inhibitory signals. Colorectal cancer(CRC)exhibiting deficient mismatch repair(dMMR)is characterized by tumor-infiltrating lymphocytes(TILs), the expression of immune ...
Takuro, Matsumoto +9 more
openaire +1 more source
The Tn antigen is the most prevalent tumor-associated carbohydrate antigen. It interacts with macrophage galactose-specific lectin(MGL)on dendric cells and macrophages, driving immune inhibitory signals. Colorectal cancer(CRC)exhibiting deficient mismatch repair(dMMR)is characterized by tumor-infiltrating lymphocytes(TILs), the expression of immune ...
Takuro, Matsumoto +9 more
openaire +1 more source
Humoral immune responses to tumor-associated carbohydrate antigens.
Seminars in cancer biology, 1992Antibodies to carbohydrate structures are quite commonly found in human sera. Normal individuals, as well as individuals with autoimmune diseases and cancer, produce antibodies reacting with a variety of carbohydrate determinants. These determinants can be expressed on glycoproteins, mucins or glycosphingolipids.
openaire +1 more source
Tumor‐associated carbohydrate antigens
Journal of Oral Pathology & Medicine, 1987E, Dabelsteen, H, Clausen
openaire +2 more sources
Tumor-Associated Carbohydrate Antigens Targeting Immunotherapy
Trends in Glycoscience and Glycotechnology, 2021openaire +1 more source
Histo-Blood Group Antigens as Tumor-Associated Carbohydrate Antigens and Ligands for Cell Adhesion
1995Since the blood group ABH antigen system was discovered by Landsteiner (1900, 1901), many scientists have worked on chemical characterization of these antigens. Early attempts to isolate the antigens from red blood cells (RBCs) were difficult because the antigens in the RBC membrane are insoluble in water and present in extremely small quantity as ...
openaire +1 more source
Aberrant expression of tumor-associated carbohydrate antigen Globo H in thyroid carcinoma.
Journal of surgical oncology, 2017The induction of tumor-associated carbohydrate antigen results from altered glycosylation in transformed cells. Globo H is a hexasaccharide glycosphingolipid overexpressed on malignancies of epithelial origin and has become an attractive vaccine target. We aimed to investigate the expression patterns and prognostic value of Globo H in thyroid neoplasms.
Shih-Ping, Cheng +5 more
openaire +1 more source