Results 1 to 10 of about 2,011,135 (332)

Identification and validation of viral antigens sharing sequence and structural homology with tumor-associated antigens (TAAs).

Journal for ImmunoTherapy of Cancer, 2021
Background The host’s immune system develops in equilibrium with both cellular self-antigens and non-self-antigens derived from microorganisms which enter the body during lifetime. In addition, during the years, a tumor may arise presenting to the immune
Luigi Buonaguro, Maria Lina Tornesello, Franco M Buonaguro, Concetta Ragone, Carmen Manolio, Beatrice Cavalluzzo, Angela Mauriello, Filippo Castiglione, Luigi Vitagliano, Emanuela Iaccarino, Menotti Ruvo, Maria Tagliamonte   +11 more
doaj   +2 more sources

Identification of B cell antigens in solid cancer: initial insights and functional implications [PDF]

Frontiers in Immunology
Cancer antigen discovery has mostly focused on T cell antigens, while antigens driving B cell responses have been largely overlooked despite representing another important branch of adaptive immune responses in cancer.
Jung-In Yang, Philip Moresco, Philip Moresco, Philip Moresco, Douglas Fearon, Douglas Fearon, Min Yao, Min Yao   +7 more
doaj   +2 more sources

Plasmacytoid dendritic cells capture and cross-present viral antigens from influenza-virus exposed cells. [PDF]

PLoS ONE, 2009
Among the different subsets of dendritic cells (DC), plasmacytoid dendritic cells (PDC) play a unique role in secreting large amounts of type I interferons upon viral stimulation, but their efficiency as antigen-presenting cells has not been completely ...
Gabrielle Lui, Olivier Manches, Juliette Angel, Jean-Paul Molens, Laurence Chaperot, Joël Plumas   +5 more
doaj   +2 more sources

Understanding MHC class I presentation of viral antigens by human dendritic cells as a basis for rational design of therapeutic vaccines

Frontiers in Immunology, 2014
Effective viral clearance requires the induction of virus-specific CD8+ cytotoxic T lymphocytes (CTL). Since dendritic cells (DC) have a central role in initiating and shaping virus-specific CTL responses, it is important to understand how DC initiate ...
Nadine eVan Montfoort, Evelyn evan der Aa, Andrea Monique Woltman   +2 more
doaj   +2 more sources

Unleashing the power of the BCG vaccine in modulating viral immunity through heterologous protection: A scoping review [PDF]

Human Vaccines & Immunotherapeutics
The Bacillus Calmette-Guérin (BCG) vaccine, used against tuberculosis for a century, shows promise in protecting against viral infections through trained/innate immunity.
Thales A. Campelo, Natália S. Oliveira, Pedro F. N. Souza, Denis F. G. de-Oliveira, Cristiane C. Frota, Paulo R. Z. Antas   +5 more
doaj   +2 more sources

Inmunohistochemical detection of pandemic SARSCoV- 2 antigens in lung tissue

Biomédica: revista del Instituto Nacional de Salud, 2022
The COVID-19 pandemic caused by the SARS-CoV-2 virus has generated globally more than 110.7 million infections and 2.4 million deaths. The severity of this infection can range from asymptomatic, mild to severe.
Jorge Alonso Rivera, Sheryll Corchuelo, Edgar Alberto Parra, Eugenio Aladino Meek, Marcela Mercado, Orlando Torres-Fernández   +5 more
doaj   +1 more source

Residual SARS-CoV-2 viral antigens detected in GI and hepatic tissues from five recovered patients with COVID-19

Gut, 2021
We read with great interest the article published by Zuo et al, which highlighted the presence of SARSCoV-2 RNA in stool samples during active and convalescence phases of COVID-19 infection.
Chun Chau Lawrence Cheung, Denise Goh, Xinru Lim, T. Tien, J. Lim, J. Lee, Benedict Tan, Zhi En Amos Tay, W. Wan, E. Chen, S. N. Nerurkar, Shihleone Loong, P. Cheow, C. Chan, Y. Koh, T. Tan, S. Kalimuddin, Wai Fei David Tai, J. Ng, J. Low, Joe Poh-Sheng Yeong, K. Lim   +21 more
semanticscholar   +1 more source

Significance of confirming Epstein-Barr virus nuclear antibody as tumor marker [PDF]

Vojnosanitetski Pregled, 2007
Backgrounnd/Aim. Study of the association between Epstein-Barr virus (EBV) and the tumors of the nasopharynx renders an opportunity to introduce causal treatment.
Stošić-Divjak Svetlana, Đukić Vojko, Boričić Ivan, Račić Alek J., Divjak Isidora, Krsmanović Velibor   +5 more
doaj   +1 more source

Potential Mimicry of Viral and Pancreatic β Cell Antigens Through Non-Spliced and cis-Spliced Zwitter Epitope Candidates in Type 1 Diabetes

Frontiers in Immunology, 2021
Increasing evidence suggests that post-translational peptide splicing can play a role in the immune response under pathological conditions. This seems to be particularly relevant in Type 1 Diabetes (T1D) since post-translationally spliced epitopes ...
Michele Mishto, Michele Mishto, Artem Mansurkhodzhaev, Teresa Rodriguez-Calvo, Teresa Rodriguez-Calvo, Juliane Liepe   +5 more
doaj   +1 more source

B-Cell Memory Responses to Variant Viral Antigens

Viruses, 2021
A central feature of vertebrate immune systems is the ability to form antigen-specific immune memory in response to microbial challenge and so provide protection against future infection.
Harry N White
doaj   +1 more source