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Inmunohistochemical detection of pandemic SARSCoV- 2 antigens in lung tissue
The COVID-19 pandemic caused by the SARS-CoV-2 virus has generated globally more than 110.7 million infections and 2.4 million deaths. The severity of this infection can range from asymptomatic, mild to severe.
Jorge Alonso Rivera+5 more
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Background The host’s immune system develops in equilibrium with both cellular self-antigens and non-self-antigens derived from microorganisms which enter the body during lifetime. In addition, during the years, a tumor may arise presenting to the immune
Luigi Buonaguro+11 more
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Recombinant Antigens in Viral Diagnosis [PDF]
DNA-fragments coding for a variety of different viral antigens have been cloned and expressed in E. coli. Selected purified recombinant antigens were used for detection of specific antibodies by the means of ELISA technique. This approach has been used for the development of four different ELISAs for the detection of HIV- and EBV-specific antibodies.
Vornhagen, R.+7 more
openaire +5 more sources
Significance of confirming Epstein-Barr virus nuclear antibody as tumor marker [PDF]
Backgrounnd/Aim. Study of the association between Epstein-Barr virus (EBV) and the tumors of the nasopharynx renders an opportunity to introduce causal treatment.
Stošić-Divjak Svetlana+5 more
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Antigen Processing of a Short Viral Antigen by Proteasomes [PDF]
Mass spectrometry (MS)-based methods coupled to reverse phase chromatography separation are a useful technology to analyze complex peptide pools that are comprised of different peptides with unrelated sequences. In antigen presentation, proteasomes generate a set of short peptides that are closely related and overlapping and in some instances may even ...
Lopez, Daniel+4 more
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Immunoelectron Microscopy of Viral Antigens [PDF]
AbstractImmunoelectron microscopy is a powerful technique for identifying viral antigens and determining their structural localization and organization within vaccines and viruses. While traditional negative staining transmission electron microscopy provides structural information, identity of components within a sample may be confounding ...
Udana Torian+3 more
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Increasing evidence suggests that post-translational peptide splicing can play a role in the immune response under pathological conditions. This seems to be particularly relevant in Type 1 Diabetes (T1D) since post-translationally spliced epitopes ...
Michele Mishto+5 more
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B-Cell Memory Responses to Variant Viral Antigens
A central feature of vertebrate immune systems is the ability to form antigen-specific immune memory in response to microbial challenge and so provide protection against future infection.
Harry N White
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HNSCC: Tumour Antigens and Their Targeting by Immunotherapy
Head and neck squamous cell carcinomas (HNSCC) are a heterogeneous group of malignant tumours typically caused by alcohol and tobacco consumption, although an increasing number of HNSCC arise due to persistent infection with high-risk human papilloma ...
Adrian von Witzleben+4 more
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Oncogenic viral antigens for engineered T cell immunotherapy: Challenges and opportunities
Viruses that cause malignancies such as hepatocellular carcinoma and cervical cancer are the cause of approximately 20% of all human cancers. In recent years, engineered T cell immunotherapy targeting tumor‐associated antigens (TAAs) has had some success
Haipeng Zhang+5 more
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