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Inmunohistochemical detection of pandemic SARSCoV- 2 antigens in lung tissue
Biomédica: revista del Instituto Nacional de Salud, 2022 The COVID-19 pandemic caused by the SARS-CoV-2 virus has generated globally more than 110.7 million infections and 2.4 million deaths. The severity of this infection can range from asymptomatic, mild to severe.
Jorge Alonso Rivera +5 more
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Journal for ImmunoTherapy of Cancer, 2021 Background The host’s immune system develops in equilibrium with both cellular self-antigens and non-self-antigens derived from microorganisms which enter the body during lifetime. In addition, during the years, a tumor may arise presenting to the immune
Luigi Buonaguro +11 more
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Significance of confirming Epstein-Barr virus nuclear antibody as tumor marker [PDF]
Vojnosanitetski Pregled, 2007 Backgrounnd/Aim. Study of the association between Epstein-Barr virus (EBV) and the tumors of the nasopharynx renders an opportunity to introduce causal treatment.
Stošić-Divjak Svetlana +5 more
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Recombinant Antigens in Viral Diagnosis [PDF]
Transfusion Medicine and Hemotherapy, 1992 DNA-fragments coding for a variety of different viral antigens have been cloned and expressed in E. coli. Selected purified recombinant antigens were used for detection of specific antibodies by the means of ELISA technique. This approach has been used for the development of four different ELISAs for the detection of HIV- and EBV-specific antibodies.
Vornhagen, R. +7 more
openaire +4 more sources
Frontiers in Immunology, 2021 Increasing evidence suggests that post-translational peptide splicing can play a role in the immune response under pathological conditions. This seems to be particularly relevant in Type 1 Diabetes (T1D) since post-translationally spliced epitopes ...
Michele Mishto +5 more
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HNSCC: Tumour Antigens and Their Targeting by Immunotherapy
Cells, 2020 Head and neck squamous cell carcinomas (HNSCC) are a heterogeneous group of malignant tumours typically caused by alcohol and tobacco consumption, although an increasing number of HNSCC arise due to persistent infection with high-risk human papilloma ...
Adrian von Witzleben +4 more
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B-Cell Memory Responses to Variant Viral Antigens
Viruses, 2021 A central feature of vertebrate immune systems is the ability to form antigen-specific immune memory in response to microbial challenge and so provide protection against future infection.
Harry N White
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Oncogenic viral antigens for engineered T cell immunotherapy: Challenges and opportunities
Medicine Advances, 2023 Viruses that cause malignancies such as hepatocellular carcinoma and cervical cancer are the cause of approximately 20% of all human cancers. In recent years, engineered T cell immunotherapy targeting tumor‐associated antigens (TAAs) has had some success
Haipeng Zhang +5 more
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Biomedicines, 2023 The gastrointestinal tract can be heavily infected by SARS-CoV-2. Being an auto-immunogenic virus, SARS-CoV-2 represents an environmental factor that might play a role in gut-associated autoimmune diseases.
Aaron Lerner +2 more
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Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics
Cell Reports, 2021 Summary: The human leukocyte antigen (HLA)-bound viral antigens serve as an immunological signature that can be selectively recognized by T cells. As viruses evolve by acquiring mutations, it is essential to identify a range of presented viral antigens ...
Adi Nagler +18 more
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