Results 1 to 10 of about 214,753 (272)

Inmunohistochemical detection of pandemic SARSCoV- 2 antigens in lung tissue

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2022
The COVID-19 pandemic caused by the SARS-CoV-2 virus has generated globally more than 110.7 million infections and 2.4 million deaths. The severity of this infection can range from asymptomatic, mild to severe.
Jorge Alonso Rivera   +5 more
doaj   +1 more source

Identification and validation of viral antigens sharing sequence and structural homology with tumor-associated antigens (TAAs).

open access: yesJournal for ImmunoTherapy of Cancer, 2021
Background The host’s immune system develops in equilibrium with both cellular self-antigens and non-self-antigens derived from microorganisms which enter the body during lifetime. In addition, during the years, a tumor may arise presenting to the immune
Luigi Buonaguro   +11 more
doaj   +1 more source

Recombinant Antigens in Viral Diagnosis [PDF]

open access: yesTransfusion Medicine and Hemotherapy, 1992
DNA-fragments coding for a variety of different viral antigens have been cloned and expressed in E. coli. Selected purified recombinant antigens were used for detection of specific antibodies by the means of ELISA technique. This approach has been used for the development of four different ELISAs for the detection of HIV- and EBV-specific antibodies.
Vornhagen, R.   +7 more
openaire   +5 more sources

Significance of confirming Epstein-Barr virus nuclear antibody as tumor marker [PDF]

open access: yesVojnosanitetski Pregled, 2007
Backgrounnd/Aim. Study of the association between Epstein-Barr virus (EBV) and the tumors of the nasopharynx renders an opportunity to introduce causal treatment.
Stošić-Divjak Svetlana   +5 more
doaj   +1 more source

Antigen Processing of a Short Viral Antigen by Proteasomes [PDF]

open access: yesJournal of Biological Chemistry, 2006
Mass spectrometry (MS)-based methods coupled to reverse phase chromatography separation are a useful technology to analyze complex peptide pools that are comprised of different peptides with unrelated sequences. In antigen presentation, proteasomes generate a set of short peptides that are closely related and overlapping and in some instances may even ...
Lopez, Daniel   +4 more
openaire   +4 more sources

Immunoelectron Microscopy of Viral Antigens [PDF]

open access: yesCurrent Protocols in Microbiology, 2019
AbstractImmunoelectron microscopy is a powerful technique for identifying viral antigens and determining their structural localization and organization within vaccines and viruses. While traditional negative staining transmission electron microscopy provides structural information, identity of components within a sample may be confounding ...
Udana Torian   +3 more
openaire   +3 more sources

Potential Mimicry of Viral and Pancreatic β Cell Antigens Through Non-Spliced and cis-Spliced Zwitter Epitope Candidates in Type 1 Diabetes

open access: yesFrontiers in Immunology, 2021
Increasing evidence suggests that post-translational peptide splicing can play a role in the immune response under pathological conditions. This seems to be particularly relevant in Type 1 Diabetes (T1D) since post-translationally spliced epitopes ...
Michele Mishto   +5 more
doaj   +1 more source

B-Cell Memory Responses to Variant Viral Antigens

open access: yesViruses, 2021
A central feature of vertebrate immune systems is the ability to form antigen-specific immune memory in response to microbial challenge and so provide protection against future infection.
Harry N White
doaj   +1 more source

HNSCC: Tumour Antigens and Their Targeting by Immunotherapy

open access: yesCells, 2020
Head and neck squamous cell carcinomas (HNSCC) are a heterogeneous group of malignant tumours typically caused by alcohol and tobacco consumption, although an increasing number of HNSCC arise due to persistent infection with high-risk human papilloma ...
Adrian von Witzleben   +4 more
doaj   +1 more source

Oncogenic viral antigens for engineered T cell immunotherapy: Challenges and opportunities

open access: yesMedicine Advances, 2023
Viruses that cause malignancies such as hepatocellular carcinoma and cervical cancer are the cause of approximately 20% of all human cancers. In recent years, engineered T cell immunotherapy targeting tumor‐associated antigens (TAAs) has had some success
Haipeng Zhang   +5 more
doaj   +1 more source

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