Fusion of Sendai virus with the target cell membrane is required for T cell cytotoxicity [PDF]
, 1978 INFECTION of mice with viruses can generate cytotoxic T lymphocytes (CTL) which show restricted specificity for target cell lysis. Specific lysis requires that the virus used to prime the target cells must be of the same type as that used to sensitise ...
A Munro +12 more
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Multiplex RT-PCR amplification of HIV genes to create a completely autologous DC-based immunotherapy for the treatment of HIV infection. [PDF]
PLoS ONE, 2008 BACKGROUND: Effective therapy for HIV-infected individuals remains an unmet medical need. Promising clinical trials with dendritic cell (DC)-based immunotherapy consisting of autologous DC loaded with autologous virus have been reported, however, these ...
Irina Tcherepanova +8 more
doaj +1 more source
Viruses, 2023 The nasal mucosa is the main gateway for entry, replication and elimination of the SARS-CoV-2 virus, the pathogen that causes severe acute respiratory syndrome (COVID-19).
Juliana Costa dos Santos +8 more
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Modeling viral coevolution: HIV multi-clonal persistence and competition dynamics [PDF]
, 2005 The coexistence of different viral strains (quasispecies) within the same host are nowadays observed for a growing number of viruses, most notably HIV, Marburg and Ebola, but the conditions for the formation and survival of new strains have not yet been ...
Altfeld +43 more
core +2 more sources
Паёми Сино, 2017 Objective: Study of the prevalence of the viral hepatitis C and viral hepatitis B in the territory of Saratov City and Saratov Region, analysis of the revealed cases and discussion of laboratory diagnostics issues.
V.V. NIKITINA +3 more
doaj +1 more source
HLA and immunodominance in viral infection: T-cell responses in protection and immunopathogenesis [PDF]
Microbiology Australia, 2021 The protective role of T cells in viral infection is well described. T cells generally mediate anti-viral immune responses via direct cytotoxicity and production of pro-inflammatory cytokines, by providing help to B cells and by promotion of memory ...
Suzi McCarthy, Allison Imrie
doaj
Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection [PDF]
, 1984 Interstitial pneumonia linked with reactivation of latent human cytomegalovirus due to iatrogenic immunosuppression can be a serious complication of bone marrow transplantation therapy of aplastic anaemia and acute leukaemia1.
A Ebeling +36 more
core +1 more source
Plasmacytoid dendritic cells capture and cross-present viral antigens from influenza-virus exposed cells. [PDF]
PLoS ONE, 2009 Among the different subsets of dendritic cells (DC), plasmacytoid dendritic cells (PDC) play a unique role in secreting large amounts of type I interferons upon viral stimulation, but their efficiency as antigen-presenting cells has not been completely ...
Gabrielle Lui +5 more
doaj +1 more source
From Superantigens to “Real” Viral Antigens [PDF]
Viral Immunology, 2020 Studies inspired by Dr. Peter Doherty led to over 16 years of research into the mouse gamma-herpesvirus, γHV68, in the Blackman laboratory. Progress on our understanding of γHV68 biology include insight into the establishment of latency, immune control of the acute and latent stages of infection and experimental vaccines, is described here.
openaire +2 more sources
PATTERN-RECOGNIZING RECEPTORS AND THE INNATE IMMUNE RESPONSE TO VIRAL INFECTION
Journal of V. N. Karazin Kharkiv National University: Series Medicine, 2019 The innate immune response to viral pathogens is crucial in mobilizing defensive reactions of an organism during the development of an acute viral infection.
Ksenia Veklich
doaj +1 more source