Results 11 to 20 of about 2,390,491 (336)

New 'Antigens' in Membranous Nephropathy.

Journal of the American Society of Nephrology, 2020
Membranous nephropathy (MN) occurs due to deposition of immune complexes along the subepithelial region of glomerular basement membrane. Two previously identified target antigens for the immune complexes, PLA2R (identified in 2009) and THSD7A (in 2014 ...
S. Sethi
semanticscholar   +1 more source

Subsets of Human Dendritic Cell Precursors Express Different Toll-like Receptors and Respond to Different Microbial Antigens

Journal of Experimental Medicine, 2001
Toll-like receptors (TLRs) are ancient microbial pattern recognition receptors highly conserved from Drosophila to humans. To investigate if subsets of human dendritic cell precursors (pre-DC), including monocytes (pre-DC1), plasmacytoid DC precursors ...
N. Kadowaki, S. Ho, S. Antonenko, R. de Waal Malefyt, R. Kastelein, F. Bazan, Yong‐jun Liu   +6 more
semanticscholar   +1 more source

Noncoding regions are the main source of targetable tumor-specific antigens

Science Translational Medicine, 2018
A proteogenomic method identifies potentially actionable tumor-specific antigens and shows that most of them are not coded by classic exons. Expanding the landscape of immunotherapy targets Most searches for druggable tumor-specific antigens (TSAs) start
Céline M. Laumont, K. Vincent, L. Hesnard, E. Audemard, É. Bonneil, J. Laverdure, Patrick Gendron, M. Courcelles, Marie-Pierre Hardy, Caroline Côté, C. Durette, Charles St-Pierre, Mohamed Benhammadi, J. Lanoix, S. Vobecky, E. Haddad, S. Lemieux, P. Thibault, C. Perreault   +18 more
semanticscholar   +1 more source

Challenges to the development of antigen-specific breast cancer vaccines [PDF]

, 2001
Continued progress in the development of antigen-specific breast cancer vaccines depends on the identification of appropriate target antigens, the establishment of effective immunization strategies, and the ability to circumvent immune escape mechanisms.
B Thurner, BJ Van den Eynde, D Jäger, DH Kaplan, Dirk Jäger, DR Leach, E Jäger, E Jäger, FO Nestle, GP Murphy, IB Runnebaum, JJ Mule, JW Hodge, K Chikamatsu, M Marchand, MA Morse, Matthew J Scanlan, MJ Scanlan, ML Disis, ML Disis, NP Restifo, P van der Bruggen, PA Lodge, RF Wang, S Morel, S Wojtowicz-Praga, T Soussi, U Sahin, U Sahin, Y Kawakami, Y Paterson, YT Chen, YT Chen   +32 more
core   +2 more sources

Babesia microti Protein BmSP44 Is a Novel Protective Antigen in a Mouse Model of Babesiosis

Frontiers in Immunology, 2020
Babesiosis caused by Babesia species imposes an increasing threat to public-health and so far, there is no effective vaccine to prevent Babesia infections. Babesia surface antigen may participate in the invasion of erythrocytes.
Hui Wang, Yao Wang, Jilei Huang, Bin Xu, Junhu Chen, Jianfeng Dai, Xia Zhou   +6 more
doaj   +1 more source

Systematic Chemoenzymatic Synthesis of O-Sulfated Sialyl Lewis x Antigens. [PDF]

, 2015
O-Sulfated sialyl Lewis x antigens play important roles in nature. However, due to their structural complexity, they are not readily accessible by either chemical or enzymatic synthetic processes.
Chen, Xi, Kenyond, Nicholas J, Li, Yanhong, Louie, Angelique Y, Muthana, Musleh M, Santra, Abhishek, Tasnima, Nova, Yu, Hai, Zeng, Jie   +8 more
core   +1 more source

Checkpoint Blockade Cancer Immunotherapy Targets Tumour-Specific Mutant Antigens

Nature, 2014
The immune system influences the fate of developing cancers by not only functioning as a tumour promoter that facilitates cellular transformation, promotes tumour growth and sculpts tumour cell immunogenicity, but also as an extrinsic tumour suppressor ...
M. Gubin, Xiuli Zhang, H. Schuster, E. Caron, J. Ward, T. Noguchi, Yulia Ivanova, J. Hundal, C. Arthur, Willem-Jan Krebber, G. Mulder, M. Toebes, M. Vesely, S. Lam, A. Korman, J. Allison, G. Freeman, A. Sharpe, Erika L. Pearce, T. Schumacher, R. Aebersold, H. Rammensee, C. Melief, E. Mardis, W. Gillanders, M. Artyomov, R. Schreiber   +26 more
semanticscholar   +1 more source

Comparative characteristics of immunohistochemical detection of M. tuberculosis antigens and mycobacteria by Ziehl–Neelsen method in lung tissue with tuberculoma during progressive course of tuberculosis

Patologìâ, 2017
The aim of the study – to compare the character of expression of M. tuberculosis antigens in immunohistochemical (IHC) study and detection of acid-fast bacilli (AFB) by Ziehl–Neelsen method in lung tissue with tuberculoma in the chronic course of ...
I. V. Liskina, O. A. Melnik, L. M. Zahaba, S. D. Kuzovkova, V. V. Kuts   +4 more
doaj   +1 more source

Enterocytes in Food Hypersensitivity Reactions

Animals, 2021
Food hypersensitivity reactions are adverse reactions to harmless dietary substances, whose causes are hidden within derangements of the complex immune machinery of humans and mammals.
Maja Krstić Ristivojević, Danijela Apostolović, Katarina Smiljanić   +2 more
doaj   +1 more source

Definition of Drosophila hemocyte subsets by cell-type specific antigens. [PDF]

, 2007
We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria.
Andó, István, Csorba, Kinga, Gateff, Elisabeth, Hultmark, Dan, Kurucz, Éva, Laurinyecz, Barbara, Márkus, Róbert, Vilmos, Péter, Váczi, Balázs, Zsámboki, János   +9 more
core   +1 more source