Results 11 to 20 of about 1,951,078 (347)

New 'Antigens' in Membranous Nephropathy.

open access: yesJournal of the American Society of Nephrology, 2020
Membranous nephropathy (MN) occurs due to deposition of immune complexes along the subepithelial region of glomerular basement membrane. Two previously identified target antigens for the immune complexes, PLA2R (identified in 2009) and THSD7A (in 2014 ...
S. Sethi
semanticscholar   +1 more source

Subsets of Human Dendritic Cell Precursors Express Different Toll-like Receptors and Respond to Different Microbial Antigens

open access: yesJournal of Experimental Medicine, 2001
Toll-like receptors (TLRs) are ancient microbial pattern recognition receptors highly conserved from Drosophila to humans. To investigate if subsets of human dendritic cell precursors (pre-DC), including monocytes (pre-DC1), plasmacytoid DC precursors ...
N. Kadowaki   +6 more
semanticscholar   +1 more source

Checkpoint Blockade Cancer Immunotherapy Targets Tumour-Specific Mutant Antigens

open access: yesNature, 2014
The immune system influences the fate of developing cancers by not only functioning as a tumour promoter that facilitates cellular transformation, promotes tumour growth and sculpts tumour cell immunogenicity, but also as an extrinsic tumour suppressor ...
M. Gubin   +26 more
semanticscholar   +1 more source

Comparative characteristics of immunohistochemical detection of M. tuberculosis antigens and mycobacteria by Ziehl–Neelsen method in lung tissue with tuberculoma during progressive course of tuberculosis

open access: yesPatologìâ, 2017
The aim of the study – to compare the character of expression of M. tuberculosis antigens in immunohistochemical (IHC) study and detection of acid-fast bacilli (AFB) by Ziehl–Neelsen method in lung tissue with tuberculoma in the chronic course of ...
I. V. Liskina   +4 more
doaj   +1 more source

Enterocytes in Food Hypersensitivity Reactions

open access: yesAnimals, 2021
Food hypersensitivity reactions are adverse reactions to harmless dietary substances, whose causes are hidden within derangements of the complex immune machinery of humans and mammals.
Maja Krstić Ristivojević   +2 more
doaj   +1 more source

Subunit Vaccine Approaches for African Swine Fever Virus

open access: yesVaccines, 2019
African swine fever virus (ASFV) is the cause of a highly fatal disease in swine, for which there is no available vaccine. The disease is highly contagious and poses a serious threat to the swine industry worldwide. Since its introduction to the Caucasus
Natasha N. Gaudreault   +1 more
doaj   +1 more source

Adjuvants and Antigen-Delivery Systems for Subunit Vaccines against Tuberculosis

open access: yesVaccines, 2021
The only licensed vaccine against tuberculosis is BCG. However, BCG has failed to provide consistent protection against tuberculosis, especially pulmonary disease in adults.
Abu Salim Mustafa
doaj   +1 more source

Noncoding regions are the main source of targetable tumor-specific antigens

open access: yesScience Translational Medicine, 2018
A proteogenomic method identifies potentially actionable tumor-specific antigens and shows that most of them are not coded by classic exons. Expanding the landscape of immunotherapy targets Most searches for druggable tumor-specific antigens (TSAs) start
Céline M. Laumont   +18 more
semanticscholar   +1 more source

Structure and genetics of Escherichia coli O antigens

open access: yesFEMS Microbiology Reviews, 2019
Escherichia coli includes clonal groups of both commensal and pathogenic strains, with some of the latter causing serious infectious diseases. O antigen variation is current standard in defining strains for taxonomy and epidemiology, providing the basis ...
B. Liu   +9 more
semanticscholar   +1 more source

Humoral immune responses in mice immunized with region of difference DNA vaccine constructs of pUMVC6 and pUMVC7

open access: yesInternational Journal of Mycobacteriology, 2017
Background: We aimed to study the antigen-specific antibody responses in mice immunized with recombinant DNA vaccines constructs of pUMVC6 and pUMVC7, containing RD1 and RD9 genes of Mycobacterium tuberculosis.
Shumaila N. M. Hanif, A S Mustafa
doaj   +1 more source

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