Results 31 to 40 of about 884,279 (321)

Comprehensive Characterization of Reference Standard Lots of HIV-1 Subtype C Gp120 Proteins for Clinical Trials in Southern African Regions

open access: yesVaccines, 2016
Two HIV-1 subtype C gp120 protein candidates were the selected antigens for several experimental vaccine regimens now under evaluation in HVTN 100 Phase I/II clinical trial aiming to support the start of the HVTN 702 Phase IIb/III trial in southern ...
Zihao Wang   +8 more
doaj   +1 more source

Babesia microti Protein BmSP44 Is a Novel Protective Antigen in a Mouse Model of Babesiosis

open access: yesFrontiers in Immunology, 2020
Babesiosis caused by Babesia species imposes an increasing threat to public-health and so far, there is no effective vaccine to prevent Babesia infections. Babesia surface antigen may participate in the invasion of erythrocytes.
Hui Wang   +6 more
doaj   +1 more source

Identificación de antígenos de quistes y trofozoítos de aislamientos colombianos de Giardia duodenalis reconocidos por IgA.

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2003
Se conoce poco acerca del papel de la IgA en la respuesta inmune de la giardiosis. El propósito de este trabajo fue identificar los antígenos estimuladores de la producción de IgA anti-Giardia duodenalis de aislamientos colombianos del parásito.
Rosana Natalia Olmos   +6 more
doaj   +1 more source

Identificación de antígenos de aislamientos colombianos de Giardia duodenalis reconocidos por IgG total y subclases.

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2003
Se conocen investigaciones realizadas sobre la respuesta inmune humoral en giardiosis. Sin embargo, estudios sobre perfiles de antígenos de quistes y de trofozoítos de Giardia duodenalis reconocidos por IgG y subclases (IgG1, IgG2, IgG3, IgG4) anti-G ...
Jenny Fabiola Hernández   +4 more
doaj   +1 more source

Trypanosoma cruzi Antigenic Proteins Shared with Acute Lymphoblastic Leukemia and Neuroblastoma

open access: yesPharmaceuticals, 2022
Background. Research studies indicate that immunization with protein extracts of Trypanosoma cruzi, the protozoan parasite that causes Chagas disease, prevents the appearance of tumors in 60% of mice injected with the murine lung carcinoma tumor line ...
Leticia Eligio García   +5 more
doaj   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Fundamental differences between natural antibodies and polyreactive immunoglobulins [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2015
A problem of similarity and differences between so-called polyreactive immunoglobulins (PRIGs) and natural antibodies (NAbs), capable of cross-reacting with some structurally dissimilar antigens, has been considered.
S. A. Bobrovnik   +2 more
doaj   +1 more source

Adjuvants and Antigen-Delivery Systems for Subunit Vaccines against Tuberculosis

open access: yesVaccines, 2021
The only licensed vaccine against tuberculosis is BCG. However, BCG has failed to provide consistent protection against tuberculosis, especially pulmonary disease in adults.
Abu Salim Mustafa
doaj   +1 more source

Identifying the genetic basis of antigenic change in influenza A(H1N1) [PDF]

open access: yesPLoS Pathogens (2016) 12(4): e1005526, 2014
Determining phenotype from genetic data is a fundamental challenge. Influenza A viruses undergo rapid antigenic drift and identification of emerging antigenic variants is critical to the vaccine selection process. Using former seasonal influenza A(H1N1) viruses, hemagglutinin sequence and corresponding antigenic data were analyzed in combination with 3-
arxiv   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

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