Results 31 to 40 of about 1,337,759 (297)
Soluble CD4 antigens in the cerebrospinal fluid as a marker of lymphocytic infiltration of the central nervous system [PDF]
Vojnosanitetski Pregled, 2004 Early diagnosis of the central nervous system (CNS) infections is a precondition of their successful treatment. However, the essential standard examination of the cerebrospinal fluid (CSF) is sometimes neither specific enough to define their basic nature,
Vrbić Miodrag +8 more
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Frontiers in Immunology, 2020 Protective vaccines for hypervariable pathogens are urgently needed. It has been proposed that amputating highly variable epitopes from vaccine antigens would induce the production of broadly protective antibodies targeting conserved epitopes. However, so far, these approaches have failed, partially because conserved epitopes are occluded in vivo and ...
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Antigen Stability Controls Antigen Presentation [PDF]
Journal of Biological Chemistry, 2004 We investigated whether protein stability controls antigen presentation using a four disulfide-containing snake toxin and three derivatives carrying one or two mutations (L1A, L1A/H4Y, and H4Y). These mutations were anticipated to increase (H4Y) or decrease (L1A) the antigen non-covalent stabilizing interactions, H4Y being naturally and frequently ...
Jean-Luc Tarride +6 more
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Vaccines, 2016 Two HIV-1 subtype C gp120 protein candidates were the selected antigens for several experimental vaccine regimens now under evaluation in HVTN 100 Phase I/II clinical trial aiming to support the start of the HVTN 702 Phase IIb/III trial in southern ...
Zihao Wang +8 more
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Biomédica: revista del Instituto Nacional de Salud, 2003 Se conocen investigaciones realizadas sobre la respuesta inmune humoral en giardiosis. Sin embargo, estudios sobre perfiles de antígenos de quistes y de trofozoítos de Giardia duodenalis reconocidos por IgG y subclases (IgG1, IgG2, IgG3, IgG4) anti-G ...
Jenny Fabiola Hernández +4 more
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Binding to Nanopatterned Antigens is Dominated by the Spatial Tolerance of Antibodies
Nature Nanotechnology, 2018 Although repetitive patterns of antigens are crucial for certain immune responses, an understanding of how antibodies bind and dynamically interact with various spatial arrangements of molecules is lacking.
Alan Shaw +9 more
semanticscholar +1 more source
Molecular typing of RhD-negative blood donors with C and/or E antigen [PDF]
Scripta Medica, 2019 Background: Most people are either RhD positive or RhD negative, but there is also a number of persons with D antigen variants. The aim of this study was to prove, by using molecular diagnostic tests, whether the RHD gene and D antigen on the red cell ...
Guzijan Gordana +4 more
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Nanoparticle Vaccines Against Infectious Diseases
Frontiers in Immunology, 2018 Due to emergence of new variants of pathogenic micro-organisms the treatment and immunization of infectious diseases have become a great challenge in the past few years.
Rashmirekha Pati +5 more
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Discriminating antigen and non-antigen using proteome dissimilarity: bacterial antigens [PDF]
Bioinformation, 2010 It has been postulated that immunogenicity results from the overall dissimilarity of pathogenic proteins versus the host proteome. We have sought to use this concept to discriminate between antigens and non-antigens of bacterial origin. Sets of 100 known antigenic and nonantigenic peptide sequences from bacteria were compared to human and mouse ...
Kamna Ramakrishnan, Darren R. Flower
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Expansion of host range as a driving force in the evolution of Toxoplasma
Memorias do Instituto Oswaldo Cruz, 2009 The apicomplexan parasite Toxoplasma gondii is unusual in being able to infect almost any cell from almost any warm-blooded animal it encounters. This extraordinary host-range contrasts with its far more particular cousins such as the various species of ...
John C Boothroyd
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