Results 31 to 40 of about 1,951,078 (347)

CcpA- and Shm2-Pulsed Myeloid Dendritic Cells Induce T-Cell Activation and Enhance the Neutrophilic Oxidative Burst Response to Aspergillus fumigatus

Frontiers in Immunology, 2021
Aspergillus fumigatus causes life-threatening opportunistic infections in immunocompromised patients. As therapeutic outcomes of invasive aspergillosis (IA) are often unsatisfactory, the development of targeted immunotherapy remains an important goal ...
Lukas Page, Julia Wallstabe, Julia Wallstabe, Jasmin Lother, Jasmin Lother, Maximilian Bauser, Olaf Kniemeyer, Olaf Kniemeyer, Lea Strobel, Vera Voltersen, Vera Voltersen, Janka Teutschbein, Janka Teutschbein, Peter Hortschansky, Peter Hortschansky, Charles Oliver Morton, Axel A. Brakhage, Axel A. Brakhage, Max Topp, Hermann Einsele, Sebastian Wurster, Juergen Loeffler   +21 more
doaj   +1 more source

DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES

Journal of Experimental Medicine, 1965
Two methods were used to demonstrate the presence of tumor-specific antigens in adenocarcinomata of the human colon: (a) rabbits were immunized with extracts of pooled colonic carcinomata, and the antitumor antisera thus produced were absorbed with a ...
P. Gold, S. Freedman
semanticscholar   +1 more source

Increased levels of invariant natural killer T lymphocytes worsen metabolic abnormalities and atherosclerosis in obese mice

Journal of Lipid Research, 2013
Obesity is a chronic inflammatory state characterized by infiltration of adipose tissue by immune cell populations, including T lymphocytes. Natural killer T (NKT) cells, a specialized lymphocyte subset recognizing lipid antigens, can be pro- or anti ...
Savitha Subramanian, Michael S. Turner, Yilei Ding, Leela Goodspeed, Shari Wang, Jane H. Buckner, Kevin O'Brien, Godfrey S. Getz, Catherine A. Reardon, Alan Chait   +9 more
doaj   +1 more source

Binding to Nanopatterned Antigens is Dominated by the Spatial Tolerance of Antibodies

Nature Nanotechnology, 2018
Although repetitive patterns of antigens are crucial for certain immune responses, an understanding of how antibodies bind and dynamically interact with various spatial arrangements of molecules is lacking.
Alan Shaw, Ian T. Hoffecker, Ioanna Smyrlaki, João Rosa, Algirdas Grevys, D. Bratlie, I. Sandlie, T. Michaelsen, J. Andersen, Björn Högberg   +9 more
semanticscholar   +1 more source

Trypanosoma cruzi Antigenic Proteins Shared with Acute Lymphoblastic Leukemia and Neuroblastoma

Pharmaceuticals, 2022
Background. Research studies indicate that immunization with protein extracts of Trypanosoma cruzi, the protozoan parasite that causes Chagas disease, prevents the appearance of tumors in 60% of mice injected with the murine lung carcinoma tumor line ...
Leticia Eligio García, María del Pilar Crisóstomo Vázquez, Víctor Alberto Maravelez Acosta, Mariana Soria Guerrero, Adrián Cortés Campos, Enedina Jiménez Cardoso   +5 more
doaj   +1 more source

Comprehensive Characterization of Reference Standard Lots of HIV-1 Subtype C Gp120 Proteins for Clinical Trials in Southern African Regions

Vaccines, 2016
Two HIV-1 subtype C gp120 protein candidates were the selected antigens for several experimental vaccine regimens now under evaluation in HVTN 100 Phase I/II clinical trial aiming to support the start of the HVTN 702 Phase IIb/III trial in southern ...
Zihao Wang, Clarisse Lorin, Marguerite Koutsoukos, David Franco, Babak Bayat, Ying Zhang, Andrea Carfi, Susan W. Barnett, Frederick Porter   +8 more
doaj   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Molecular typing of RhD-negative blood donors with C and/or E antigen [PDF]

Scripta Medica, 2019
Background: Most people are either RhD positive or RhD negative, but there is also a number of persons with D antigen variants. The aim of this study was to prove, by using molecular diagnostic tests, whether the RHD gene and D antigen on the red cell ...
Guzijan Gordana, Milosavić Milanka, Radojković-Sredić Danijela, Lilić Marko, Jukić Biljana   +4 more
doaj  

Identificación de antígenos de aislamientos colombianos de Giardia duodenalis reconocidos por IgG total y subclases.

Biomédica: revista del Instituto Nacional de Salud, 2003
Se conocen investigaciones realizadas sobre la respuesta inmune humoral en giardiosis. Sin embargo, estudios sobre perfiles de antígenos de quistes y de trofozoítos de Giardia duodenalis reconocidos por IgG y subclases (IgG1, IgG2, IgG3, IgG4) anti-G ...
Jenny Fabiola Hernández, Sofía Duque, Adriana Arévalo, Rafael Guerrero, Rubén Santiago Nicholls   +4 more
doaj   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source