Results 71 to 80 of about 6,856 (183)

Leishmanicidal compounds of Nectria pseudotrichia, an endophytic fungus isolated from the plant Caesalpinia echinata (Brazilwood)

Memorias do Instituto Oswaldo Cruz
BACKGROUND In a screen of extracts from plants and fungi to detect antileishmanial activity, we found that the ethyl acetate extract of the fungus Nectria pseudotrichia, isolated from the tree Caesalpinia echinata (Brazilwood), is a promising source of ...
Betania Barros Cota, Luiza Guimarães Tunes, Daniela Nabak Bueno Maia, Jonas Pereira Ramos, Djalma Menezes de Oliveira, Markus Kohlhoff, Tânia Maria de Almeida Alves, Elaine Maria Souza-Fagundes, Fernanda Fraga Campos, Carlos Leomar Zani   +9 more
doaj   +1 more source

Antileishmanial and Cytotoxic Compounds from Valeriana wallichii and Identification of a Novel Nepetolactone Derivative

Molecules, 2015
The chloroform extract of Valeriana wallichii (V. wallichii) rhizomes was investigated to elucidate the structures responsible for reported antileishmanial activity.
Jan Glaser, Martina Schultheis, Heidrun Moll, Banasri Hazra, Ulrike Holzgrabe   +4 more
doaj   +1 more source

Brain Involvement in Leishmaniasis

Cell Biochemistry and Function, Volume 44, Issue 4, April 2026.
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Camila S. Freitas, Eduardo A. F. Coelho, Myron Christodoulides   +2 more
wiley   +1 more source

Hexane Fraction of Cinnamomum verum Leaves Induces Apoptosis-like Cell Death in Leishmania amazonensis

Sci
Leishmaniasis is a serious public health issue, but current treatments have significant adverse effects. Although the leishmanicidal potential of Cinnamomum verum (cinnamon) bark is well known, the therapeutic potential of its leaves for leishmaniosis is
Caroline Martins Jesus, Fernanda Farias Costa, Louriane Nunes Gomes, Luis Douglas Miranda Silva, Yaron Santos Alencar, Richard Pereira Dutra, Cláudia Quintino da Rocha, Lucilene Amorim Silva, Aramys Silva Reis   +8 more
doaj   +1 more source

Evaluation of antioxidant, antimicrobial and cytotoxic potential in Artemisia vulgaris L.

Romanian Journal of Laboratory Medicine, 2018
Artemisia vulgaris L. (Mugwort or Afsantin) has been used to treat various diseases since ancient times by the inhabitants of Himalayan region-Pakistan. Methanolic fractions (HA1-HA9) obtained from the aerial parts of A. vulgaris were evaluated for their
Hamad Asad, Arfan Muhammad, Khan Shujaat Ali, Fatima Nighat, Abbasi Arshad Mehmood, Mannan Abdul   +5 more
doaj   +1 more source

Antileishmanial activity of mycobacillin.

The Journal of Antibiotics, 1977
Mycobacillin, a cyclic polypeptide antifungal antibiotic effectively inhibits the growth of promastigote form of the protozoal organism, Leishmania donovani, strain 81 in liquid medium. Oxygen uptake by intact cells of the protozoa with exogenous glucose is appreciably reduced within first 30 minutes in presence of the antibiotic at a concentration of ...
T. K. CHATTOPADHYAY, S. N. GHATAK, A. N. BHADURI, D. K. GHOSH   +3 more
openaire   +3 more sources

Thymus syriacus Essential Oil Extract: Potential Antileishmanial Activity Induced by an Apoptotic-like Death

Antibiotics
Background: Chemotherapy continues to be the cornerstone for the management of leishmaniasis. The preferred medications are pricey and have a number of unfavorable side effects.
Basem Battah, Teresa Chianese, Luigi Rosati, Giacomo Petretto, Chadi Soukkarieh, Marco Ferrari, Vittorio Mazzarello, Aleksandra Barac, Aleksandar Peric, Matthew Gavino Donadu   +9 more
doaj   +1 more source

In Vitro and In Silico Assessments of Curcuminoids and Turmerones from Curcuma longa as Novel Inhibitors of Leishmania infantum Arginase

Pharmaceuticals
Background/Objectives: The anti-Leishmania potential of Curcuma longa and its derivatives, such as curcuminoids, is well-established, yet their mechanisms of action remain underexplored. This study investigates the inhibitory effects of C. longa extracts
Flora F. S. Spíndola, Anderson S. Pinheiro, Maria Athana Mpalantinos, Jefferson R. A. Silva, Walter S. M. F. Neto, Raissa A. Conceição, Eduarda M. Barreto, Barbara A. Abrahim-Vieira, Carlos R. Rodrigues, Alessandra M. T. Souza, Dirlei Nico, Ana Claudia F. Amaral, Andreza R. Garcia, Igor A. Rodrigues   +13 more
doaj   +1 more source

Evaluation of antileishmanial activity of plants used in Indian traditional medicine

Bangladesh Journal of Pharmacology, 2015
The present study was aimed at in vitro antileishmanial screening of ten plants used in the traditional medicine in India. MTT method was used to evaluate the cell death after application of 100, 250, 350 and 500 ?g/mL of the methanolic extracts followed
Arushdeep Sidana, Umar Farooq
doaj   +1 more source

Molecular target of the antileishmanial action of sinefungin [PDF]

Antimicrobial Agents and Chemotherapy, 1987
Sinefungin, a natural nucleoside isolated from cultures of Streptomyces incarnatus and S. griseolus, is structurally related to S-adenosylhomocysteine and S-adenosylmethionine. Sinefungin has been shown to inhibit the development of various fungi and viruses, but its major attraction to date resides in its potent antiparasitic activity.
openaire   +2 more sources