Results 1 to 10 of about 4,028,312 (182)

Bibliometric analysis of antimalarial drug resistance [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology
BackgroundMalaria has always been a serious infectious disease prevalent in the world. Antimalarial drugs such as chloroquine and artemisinin have been the main compounds used to treat malaria.
Jialu Zhang   +7 more
doaj   +4 more sources

Molecular Profiles of Multiple Antimalarial Drug Resistance Markers in Plasmodium falciparum and Plasmodium vivax in the Mandalay Region, Myanmar

open access: yesMicroorganisms, 2022
Emergence and spreading of antimalarial drug resistant malaria parasites are great hurdles to combating malaria. Although approaches to investigate antimalarial drug resistance status in Myanmar malaria parasites have been made, more expanded studies are
Hương Giang Lê   +10 more
doaj   +1 more source

Molecular detection of human Plasmodium species using a multiplex real time PCR

open access: yesScientific Reports, 2023
Molecular detection methods have revealed higher sensitivity and specificity than conventional microscopy or rapid diagnostic tests for malaria diagnosis.
Yassamine Lazrek   +7 more
doaj   +1 more source

Determination of different social groups’ level of knowledge about malaria in a multicultural Amazonian cross-border context

open access: yesBMC Public Health, 2023
Background A steady decline in the number of cases of malaria was observed in the 2000s in French Guiana. This enabled regional health policies to shift their public health goal from control to elimination.
Mélanie Gaillet   +12 more
doaj   +1 more source

Assessing the Roles of Molecular Markers of Antimalarial Drug Resistance and the Host Pharmacogenetics in Drug-Resistant Malaria

open access: yesJournal of Tropical Medicine, 2022
Malaria caused by the Plasmodium parasites is a major public health concern in malaria-endemic regions with P. falciparum causing the most severe form of the disease. The use of antimalarial drugs for the management of the disease proves to be one of the
Peter Hodoameda   +2 more
doaj   +1 more source

Molecular assays for antimalarial drug resistance surveillance: A target product profile. [PDF]

open access: yesPLoS ONE, 2018
Antimalarial drug resistance is a major constraint for malaria control and elimination efforts. Artemisinin-based combination therapy is now the mainstay for malaria treatment.
Christian Nsanzabana   +16 more
doaj   +1 more source

Absence of Association between Methylene Blue Reduced Susceptibility and Polymorphisms in 12 Genes Involved in Antimalarial Drug Resistance in African Plasmodium falciparum

open access: yesPharmaceuticals, 2021
Half the human population is exposed to malaria. Plasmodium falciparum antimalarial drug resistance monitoring and development of new drugs are major issues related to the control of malaria.
Mathieu Gendrot   +10 more
doaj   +1 more source

Current and emerging target identification methods for novel antimalarials

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2022
New antimalarial compounds with novel mechanisms of action are urgently needed to combat the recent rise in antimalarial drug resistance. Phenotypic high-throughput screens have proven to be a successful method for identifying new compounds, however, do ...
Matthew P. Challis   +2 more
doaj   +1 more source

The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957

open access: yesScientific Reports, 2021
New antimalarial therapeutics are needed to ensure that malaria cases continue to be driven down, as both emerging parasite resistance to frontline chemotherapies and mosquito resistance to current insecticides threaten control programmes.
Celia Miguel-Blanco   +18 more
doaj   +1 more source

ANTI-MALARIAL DRUG RESISTANCE

open access: yesMajalah Kedokteran Andalas, 2014
AbstrakTujuan studi ini adalah untuk menjelaskan mekanisme resistensi parasit malaria danusaha-usaha yang dapat dilakukan untuk menghadapi munculnya strain parasit yangresisten terhadap artemisinin.
Yenni Yusuf
doaj   +1 more source

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