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Antimicrobial Peptides [PDF]

Pharmaceuticals, 2013
The rapid increase in drug-resistant infections has presented a serious challenge to antimicrobial therapies. The failure of the most potent antibiotics to kill “superbugs” emphasizes the urgent need to develop other control agents.
Ali Adem Bahar, Dacheng Ren
doaj   +5 more sources

Marine Invertebrate Peptides: Antimicrobial Peptides [PDF]

Frontiers in Microbiology, 2021
Antimicrobial peptides are an important component of many organisms’ innate immune system, with a good inhibitory or killing effect against the invading pathogens. As a type of biological polypeptide with natural immune activities, antimicrobial peptides
Ran Wu, Jiri Patocka, Jiri Patocka, Eugenie Nepovimova, Patrik Oleksak, Martin Valis, Wenda Wu, Wenda Wu, Kamil Kuca, Kamil Kuca   +9 more
doaj   +3 more sources

Probing protein sequences as sources for encrypted antimicrobial peptides. [PDF]

PLoS ONE, 2012
Starting from the premise that a wealth of potentially biologically active peptides may lurk within proteins, we describe here a methodology to identify putative antimicrobial peptides encrypted in protein sequences.
Guilherme D Brand, Mariana T Q Magalhães, Maria L P Tinoco, Francisco J L Aragão, Jacques Nicoli, Sharon M Kelly, Alan Cooper, Carlos Bloch   +7 more
doaj   +8 more sources

Targeted antimicrobial peptides [PDF]

Frontiers in Immunology, 2012
The existence of natural antimicrobial substances, contributing to the mechanisms of host defenses, has been recognized since the late nineteenth century. In 1963, the in vitro antibacterial activity of leukocyte extracts was attributed to basic proteins.
Marc eDevocelle
doaj   +3 more sources

Antimicrobial peptides [PDF]

Current Biology, 2016
Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring molecules that are produced as a first line of defense by all multicellular organisms. These proteins can have broad activity to directly kill bacteria, yeasts, fungi, viruses and even cancer cells.
Zhang, Ling-juan, Gallo, Richard L.
  +5 more sources

Perspective: A proposal on solutions of modern supply chain construction for lactoferrin

Journal of Dairy Science, 2023
: Lactoferrin is an iron-binding glycoprotein of the transferrin family that is found in most bodily fluids of mammals and has a variety of biological and beneficial functions, with great importance in health enhancement as a supplement for humans and ...
Ruoyu Mao, Xuanxuan Ma, Ya Hao, Guihong Pen, Xueling Zheng, Na Yang, Da Teng, Jianhua Wang   +7 more
doaj   +1 more source

Pharmacokinetics and Pharmacodynamics of Fungal Defensin NZX Against Staphylococcus aureus-Induced Mouse Peritonitis Model

Frontiers in Microbiology, 2022
Staphylococcus aureus (S. aureus) is one of the most common pathogenic bacteria responsible for causing a life-threatening peritonitis disease. NZX, as a variant of fungal defensin plectasin, displayed potent antibacterial activity against S. aureus.
Xueling Zheng, Xueling Zheng, Xueling Zheng, Na Yang, Na Yang, Na Yang, Ruoyu Mao, Ruoyu Mao, Ruoyu Mao, Ya Hao, Ya Hao, Ya Hao, Da Teng, Da Teng, Da Teng, Jianhua Wang, Jianhua Wang, Jianhua Wang   +17 more
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Plectasin: from evolution to truncation, expression, and better druggability

Frontiers in Microbiology, 2023
Non-computational classical evolution analysis of plectasin and its functional relatives can especially contribute tool value during access to meet requirements for their better druggability in clinical use.
Xuan Li, Xuan Li, Xuan Li, Ya Hao, Ya Hao, Ya Hao, Na Yang, Na Yang, Na Yang, Ruoyu Mao, Ruoyu Mao, Ruoyu Mao, Da Teng, Da Teng, Da Teng, Jianhua Wang, Jianhua Wang, Jianhua Wang   +17 more
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Andrographolide and 4-Phenylbutyric Acid Administration Increase the Expression of Antimicrobial Peptides Beta-Defensin-1 and Cathelicidin and Reduce Mortality in Murine Sepsis

Antibiotics, 2022
Antibiotic resistance is a global threat and requires the search for new treatment strategies. Natural antimicrobial peptides (AMPs) have pronounced antibacterial, antiviral, antifungal, and antitumor activity.
Albert Bolatchiev, Vladimir Baturin, Elizaveta Bolatchieva   +2 more
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Research progress on antimicrobial peptides in terms of the prevention and treatment of dental caries

口腔疾病防治, 2023
Antimicrobial peptides have antibacterial effects on various pathogenic microorganisms, including natural antimicrobial peptides and synthetic antimicrobial peptides.
ZHU He , CHENG Xingqun, WU Hongkun
doaj   +1 more source