Results 31 to 40 of about 242,768 (165)
Destabilization of α-helical structure in solution improves bactericidal activity of antimicrobial peptides: Opposing effects on bacterial and viral targets [PDF]
, 2016 We have previously examined the mechanism of antimicrobial peptides on the outer membrane of vaccinia virus. Here we show that the formulation of peptides LL37 and magainin-2B amide in polysorbate 20 (Tween-20™) results in greater reductions in virus ...
Beck, Konrad +4 more
core +2 more sources
Russian Journal of Genetics: Applied Research, 2013 Antimicrobial peptides (AMPs) are low-molecular-weight defense polypeptides, produced in all living organisms either constitutively or upon perception of signals from pathogenic microorganisms. They are important components of the immune system in both animals and plants. AMPs differ in structure and mode of action. Most of them belong to cysteine-rich
T. I. Odintsova +7 more
openaire +2 more sources
Evidence Supporting an Antimicrobial Origin of Targeting Peptides to Endosymbiotic Organelles
Cells, 2020 Mitochondria and chloroplasts emerged from primary endosymbiosis. Most proteins of the endosymbiont were subsequently expressed in the nucleo-cytosol of the host and organelle-targeted via the acquisition of N-terminal presequences, whose evolutionary ...
Clotilde Garrido +4 more
doaj +1 more source
A novel antibacterial peptide derived from Crocodylus siamensis haemoglobin hydrolysate induces membrane permeabilization causing iron dysregulation, oxidative stress and bacterial death [PDF]
, 2017 Aims A novel antibacterial peptide from Crocodylus siamensis haemoglobin hydrolysate (CHH) was characterized for antimicrobial activity. Methods and Results CHHs were hydrolysed for 2 h (2 h-CHH), 4 h (4h-CHH), 6 h (6 h-CHH) and 8 h (8 h-CHH). The
Adje +29 more
core +2 more sources
Recent advances in the field of antimicrobial peptides in inflammatory diseases
Advanced Biomedical Research, 2013 Antimicrobial peptides are cationic molecules, which participate in multiple aspects of the immune response including the control of inflammatory diseases, characteristic that make these molecules attractive as therapeutic tools.
Patricia Méndez-Samperio
doaj +1 more source
Molecules, 2021 The increasing antimicrobial-resistant prevalence has become a severe health problem. It has led to the invention of a new antimicrobial agent such as antimicrobial peptides.
Rima Erviana +7 more
doaj +1 more source
Antimicrobial peptides and proteins of the horse - insights into a well-armed organism
Veterinary Research, 2011 Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with ...
Bruhn Oliver +3 more
doaj +1 more source
AntibioticsAntimicrobial peptides (AMPs) are antibiotic candidates; however, their instability and protease susceptibility limit clinical applications. In this study, the polylactic acid–glycolic acid (PLGA)–polyvinyl alcohol (PVA) drug delivery system was screened
Xuanxuan Ma +6 more
doaj +1 more source
Heliyon, 2019 Peptides are secreted by different cell types and are trendy therapeutic agents that have attracted attention for the treatment of several diseases such as infections.
Reza Esfandiyari +5 more
doaj +1 more source
Serum stabilities of short tryptophan- and arginine-rich antimicrobial peptide analogs. [PDF]
PLoS ONE, 2010 Several short antimicrobial peptides that are rich in tryptophan and arginine residues were designed with a series of simple modifications such as end capping and cyclization.
Leonard T Nguyen +5 more
doaj +1 more source