Results 171 to 180 of about 1,226 (209)
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Antimutagenesis and Antimutagens
Human Physiology, 2018The article discusses the history and current status of research in the field of antimutagenesis and the prospects of application of antimutagenic agents. Basing on personal experience and literature data, we analyzed the mechanisms of antimutagenic action and the methods for the investigation of antimutagenic agents and discussed the experience and ...
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Trends in Food Science & Technology, 1994
Abstract Foods are complex mixtures containing both carcinogenic and anticarcinogenic substances. During the past ten years, there has been increasing interest in individuating and establishing the roles of the various antimutagens/anticarcinogens in the diet. Several compounds appear to protect against both mutagenic and carcinogenic effects.
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Abstract Foods are complex mixtures containing both carcinogenic and anticarcinogenic substances. During the past ten years, there has been increasing interest in individuating and establishing the roles of the various antimutagens/anticarcinogens in the diet. Several compounds appear to protect against both mutagenic and carcinogenic effects.
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Antimutagenic and Anticarcinogenic Mechanisms of Aminothiols
1991Glutathione (GSH) and synthetic aminothiols, such as N-acetylcysteine (NAC), play an important role as inhibitors of mutagenesis and carcinogenesis (1). The present paper will update the studies carried out in our laboratories, which will be discussed according to a mechanistic approach.
DE FLORA, SILVIO +5 more
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Antimutagenic Activity of Berry Extracts
Journal of Medicinal Food, 2004Plants are proven sources of useful anti-tumor and chemopreventative compounds. Hence, identification of phytochemicals useful in dietary prevention and intervention of cancer is of paramount importance. The initial step in the formation of cancer is damage to the genome of a somatic cell producing a mutation in an oncogene or a tumor-suppressor gene ...
S, Hope Smith +6 more
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Antimutagens from Momordica charantia
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1990The antimutagenic principle of the green fruits of Momordica charantia was shown by the micronucleus test to be an intractable mixture of novel acylglucosylsterols. The antimutagens were extracted from the green fruits with ethanol and isolated from the bioactive petroleum ether and carbon tetrachloride extracts by repeated and sequential flash column ...
A P, Guevara +3 more
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The Concept of Activity Profiles of Antimutagens
1990There is considerable evidence that gene and chromosomal mutations are important factors in carcinogenesis (1,45). It follows, therefore, that the incidence of cancer can be reduced by decreasing the rate of mutation. The most obvious way to decrease the rate of mutation is to determine which environmental agents are mutagenic and then to reduce or ...
M D, Waters +3 more
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Antimutagenic effect of an antioxidant in mammals
Mutation Research/Genetic Toxicology, 1984To test a possible antimutagenic activity of ethoxyquin (EQ) in bone-marrow cells, 3 cytogenetic tests with distinct genetic end-points were applied. Cyclophosphamide (CPA), serving as test mutagen, and the antioxidant EQ were administered immediately following each other to Chinese hamsters by stomach tube.
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Antimutagenic Investigations on Commercial Yogurt
1993The role of diet in the etiology of cancer has received increasing attention in the last ten years (1-5). Consumption of milk reduced the incidence of human stomach cancer induced by alkylating agents (6). Human subjects (7) and experimental animals (8) receiving dietary supplements of Lactobacillus acidophilus exhibited significantly lower levels of ...
C, Della Croce +4 more
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Assessment of antimutagenicity and anticarcinogenicity
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1992DE FLORA, SILVIO +2 more
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