Results 151 to 160 of about 1,226 (209)
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Molecular and General Genetics MGG, 1977
In E. coli strain 91P containing the mutator gene mutT-, caffeine, spermine and quinacrine, but not guanosine, act as antimutagens, reducing the frequencies of mutation from ara- leads to Ara.
C H, Clarke, D M, Shankel
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In E. coli strain 91P containing the mutator gene mutT-, caffeine, spermine and quinacrine, but not guanosine, act as antimutagens, reducing the frequencies of mutation from ara- leads to Ara.
C H, Clarke, D M, Shankel
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Antimutagenic effects of mushrooms
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1990A heat-resistant factor in ethanol extracts of the fungus Craterellus cornucopioides completely inhibited the mutagenicity of aflatoxin B1, benzo[a]pyrene, the acridine half mustard ICR-191 and 2-nitrofluorene in a forward-mutation system using Salmonella typhimurium TM677 (screening for 8-azaguanine resistance).
A, Grüter, U, Friederich, F E, Würgler
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Antimutagenic Activity of Lipidovit
Bulletin of Experimental Biology and Medicine, 2004Antimutagenic properties of Lipidovit produced from the biomass of Blakeslea trispora fungi was studied by its effect on induction of chromosome aberrations by chemical mutagens dioxidine and cyclophosphamide in mouse bone marrow cells. Antimutagenic activity of Lipidovit depended on the scheme of treatment.
P B, Avchieva +6 more
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Polyamines and their potential to be antimutagens
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1997In order to determine the antimutagenic potential of polyamines, modified Ames tests were performed. Polyamines spermine, spermidine and putrescine all showed antimutagenic potential against EMS-induced reversions. In addition, the polyamines spermidine and putrescine showed potential to reduce the number of spontaneous revertants in modified Ames ...
S P, Pillai, D M, Shankel
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Antimutagenicity in Euglena gracilis
Mutation Research Letters, 1994The genotoxic effect of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and furadantine (Fu) was significantly decreased by standard antimutagens (ascorbic acid, alpha-tocopherol, chlorophyllin and sodium selenite) in the unicellular flagellate Euglena gracilis. The effects of these compounds were verified also by a bacterial test in which three strains of
P, Foltínová +2 more
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Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1996
Following a brief review of recent discoveries in the field of natural antimutagenic and tumor chemopreventive agents, contemporary findings in the author's laboratories employing the direct acting mutagen, ethyl methanesulfonate, in modified Ames tests and eukaryotic murine FM3A mammary tumor cells modified to be subject to thymidine-less death are ...
L A, Mitscher +3 more
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Following a brief review of recent discoveries in the field of natural antimutagenic and tumor chemopreventive agents, contemporary findings in the author's laboratories employing the direct acting mutagen, ethyl methanesulfonate, in modified Ames tests and eukaryotic murine FM3A mammary tumor cells modified to be subject to thymidine-less death are ...
L A, Mitscher +3 more
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Antimutagens and their Modes of Action
1986Agents suppressing cellular mutagenesis have been known for some time, and their modes of action have been analyzed in the field of bacterial genetics (8, 49). More recently, a number of mutagens have been detected in our environment and their genotoxicities recognized (45).
T, Kada, T, Inoue, T, Ohta, Y, Shirasu
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Evidence for the antimutagenicity and the mutagenicity of selenium
Biological Trace Element Research, 1980Evidence is summarized for the antimutagenicity as well as the mutagenicity of selenium. In general, antimutagenicity predominates at physiological levels, while mutagenicity occurs at 3 to 1000 times normal physiological levels.
Raymond J Shamberger, R J Shamberger
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Antimutagenic activity of spearmint
Environmental and Molecular Mutagenesis, 2004AbstractThe antimutagenic activity of spearmint (Mentha spicata), a popular food flavoring agent, was studied in the Salmonella assay. Spearmint leaves were brewed in hot water for 5 min at concentrations up to 5% (w/v), and the water extracts were tested against the direct‐acting mutagens 4‐nitro‐1,2‐phenylenediamine (NPD) and 2‐hydroxyamino‐3‐methyl ...
Tian-Wei, Yu +2 more
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On the antimutagenic effect of spermine
Experientia, 1967La spermine n'offre aucune protection contre la reversion des mutants derII chezEscherichia coliphage T4, quoiqu'on ait constate qu'elle antimutagenique chezE. coli.
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