Results 61 to 70 of about 1,026,399 (319)

Ginger (Zingiber officinale) Root Capsules Enhance Analgesic and Antioxidant Efficacy of Diclofenac Sodium in Experimental Acute Inflammation [PDF]

, 2023
Our study aimed to evaluate the analgesic and antioxidant effects of ginger (Zingiber officinale) root capsule extract (GRCE) in addition to diclofenac (D) sodium treatment in carrageenan-induced acute inflammation (AI).
Ioana Corina Bocșan, Ioana Boarescu, Dan Gheban, Raluca Maria Pop, Adriana Elena Bulboacă, Anca Dana Buzoianu, Paul-Mihai Boarescu, Sorana D. Bolboacă   +7 more
core   +1 more source

Anti-Inflammatory Effects of Aptamin C in Pulmonary Fibrosis Induced by Bleomycin

Pharmaceuticals
Background/Objectives: Vitamin C is a well-known antioxidant with antiviral, anticancer, and anti-inflammatory properties. However, its therapeutic applications are limited by rapid oxidation due to heat and light sensitivity.
Seulgi Shin, Hyejung Jo, Tomoyo Agura, Seoyoun Jeong, Hyovin Ahn, Soyoung Pang, June Lee, Jeong-Ho Park, Yejin Kim, Jae Seung Kang   +9 more
doaj   +1 more source

NADPH Oxidase (Rboh) Activity is Up Regulated during Sweet Pepper (Capsicum annuum L.) Fruit Ripening

Antioxidants, 2019
In plants, NADPH oxidase (NOX) is also known as a respiratory burst oxidase homolog (Rboh). This highly important enzyme, one of the main enzymatic sources of superoxide radicals (O2•−), is involved in the metabolism of reactive oxygen and ...
Ángela Chu-Puga, Salvador González-Gordo, Marta Rodríguez-Ruiz, José M. Palma, Francisco J. Corpas   +4 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Potential of Lignins as Antioxidant Additive in Active Biodegradable Packaging Materials [PDF]

, 2013
Lien vers la version éditeur: http://link.springer.com/article/10.1007/s10924-013-0570-6Due to their polyphenolic structure lignins bear a number of interesting functional properties, such as antioxidant activity.
LOUAIFI, Abderrahim, BAUMBERGER, Stéphanie, DOMENEK, Sandra, GUINAULT, Alain   +3 more
core   +1 more source

Alloferon and IL-22 receptor expression regulation on the pathogenesis of imiquimod-induced psoriasis

Scientific Reports
Psoriasis is an immune-mediated inflammatory skin disease. IL-22, a proinflammatory cytokine, is implicated in psoriasis pathogenesis; however, there is currently no established biological treatment targeting IL-22 or its receptor, IL-22Rα.
Tomoyo Agura, Hyejung Jo, Seulgi Shin, Yoojin Jang, Chong Won Choi, In Su Gwak, Jae Seung Kang, Yejin Kim   +7 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Design and synthesis of novel thiophenecarbohydrazide, thienopyrazole and thienopyrimidine derivatives as antioxidant and antitumor agents [PDF]

, 2010
Etilni ester 2-amino-5-acetil-4-metil-tiofen-3-karboksilne kiseline (1) i 5-acetil-2-amino-4-metiltiofen-3-karbohidrazid (2) sintetizirani su i upotrebljeni kao reaktanti u sintezi novih spojeva 1-(5-amino-4-(3,5-dimetil-1H-pirazol-1-karbonil)-3 ...
Farid Badria, FARID ABD-ELRAHEEM BADRIA, ABU-HASHEM, AMEEN ALI, EL-SHEHRY, MOHAMED FATHY, MOHAMED FATHY EL-SHEHRY, Mohamed El-Shehry, Ameen Abu-Hashem, BADRIA, FARID ABD-ELRAHEEM, AMEEN ALI ABU-HASHEM   +8 more
core   +2 more sources

Antioxidative activity of a novel antioxidant resorcimoline

Free Radical Research
During the synthesis of a known drug, we synthesized a novel compound impromptu, which we have named resorcimoline. This compound exhibited significant antioxidative activity. In this report, we present the concentration-dependent free radical scavenging activity of resorcimoline against various free radical species.
Osamu, Tokumaru, Akihiro, Higuchi, Takayuki, Kawashima, Kazue, Ogata, Kazuhiro, Ueno, Takanori, Inoue, Shinji, Miyamoto   +6 more
openaire   +2 more sources