Results 181 to 190 of about 301,453 (295)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Effect of Different Interstocks on Fruit Quality, Amino Acids, and Antioxidant Capacity in 'Yuanxiaochun' Citrus. [PDF]

Antioxidants (Basel)
Wang T, Sun G, He S, Liao L, Xiong B, Wang Z.   +5 more
europepmc   +1 more source

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

Enhancing antioxidant capacity and reducing asthma risk: the impact of zinc and iron on molecular pathways. [PDF]

Clin Exp Med
Yu Z, Li Z, Ma Y, Ma Y, Wang H.
europepmc   +1 more source

Effects of Dietary Allium Mongolicum  Regel Powder Supplementation on the Growth Performance, Meat Quality, Antioxidant Capacity and Muscle Fibre Characteristics of Fattening Angus Calves

Wangjing Liu, Huixia Gao, Jianjian He, Chenxu Sun, AIhuan Yu, Yaodi Xie, Haibo Yao, He Wang, Yueyan Duan, Jinsheng Hu, Defu Tang, Zhaomin Lei, Ran Tao   +12 more
openalex   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Effects of green tea dust on the biochemical parameters, antioxidant capacity, and intestinal microbiota composition in goose. [PDF]

Front Vet Sci
Gu Z, Xu W, Tian Y, Lu L, Chen G.
europepmc   +1 more source

Nano Zinc Oxide (Zno Nps) Alleviates Salt Stress Damage by Regulating Ionic Homeostasis and Enhancing Antioxidant Capacity in Rapeseed (Brassica Napus L.) Seedlings

Xiaoling Zhang, Lei Zheng, Maria Batool, Chunyu Zhang, Jinxiong Shen, Jing Wang, Jie Kuai, Jie Zhao, Zhenghua Xu, Bo Wang, Guangsheng Zhou   +10 more
openalex   +1 more source

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source

Influence of different extraction solvents on phytochemical content and antioxidant capacity extracted from pulp and flower of dessert and cooking bananas [PDF]

, 2017
Nurhana Nadia Ramlan, Azzreena Mohamad Azzeme, K.N.M. Padzil, Maziah Mahmood   +3 more
openalex