Results 191 to 200 of about 394,333 (360)

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Ultrasonic exposure enhances the body's antioxidant capacity. [PDF]

J Clin Biochem Nutr
Niwa R, Ichikawa H, Shimada H, Indo HP, Minamiyama Y, Majima HJ, Oowada S, Akiyama I.   +7 more
europepmc   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

Synthesis, antioxidant capacity and aggregation of carotenoid-curcumin conjugates and hybrids. [PDF]

PLoS One
Jijón S, Czett D, Böddi K, Gulyás-Fekete G, Nagy V, Takátsy A, Balogh GT, Deli J, Agócs A.   +8 more
europepmc   +1 more source

Dietary effects of Bacillus subtilis fmbj on growth performance, small intestinal morphology, and its antioxidant capacity of broilers

, 2018
Kaiwen Bai, Chengcheng Feng, Luyi Jiang, Ligen Zhang, Jingfei Zhang, Lili Zhang, Tian Wang   +6 more
openalex   +1 more source

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

Advanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou, Qiming Zhai, Zhihao Yao, Qing Li, Yan Yang, Si Wang, Chao Huang, Liangjing Xin, Tao Chen, Jinlin Song   +9 more
wiley   +1 more source

The Effects of Tributyrin on Immune Function, Antioxidant Capacity, and Metabolomics in Young Pigeons. [PDF]

Animals (Basel)
Wu R, Deng L, Li H, Yao Y, Wu Y, Lu Q, You G, Jiang T.   +7 more
europepmc   +1 more source

Prospective use of fruit byproducts in Colombia according to their antioxidant capacity

, 2020
Ciliana Flórez-Montes, Óscar Marino Mosquera-Martínez, Andrés Felipe Rojas González   +2 more
openalex   +2 more sources

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Polyphenols, ascorbate and antioxidant capacity of the Kei-apple (Dovyalis caffra)

, 2006
Tersia De Beer
openalex   +1 more source